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Weekend Infusion Rn Jobs in Jacksonville, FL (NOW HIRING)

PRN Home Infusion Nurse

Saint Augustine, FL · On-site

$32.25 - $42.75/hr

An Infusion Nurse I is a licensed registered nurse who provides basic direct patient care to patients in the home, or in an alternate infusion site, to ensure patient safety with continuity and ...

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Weekend Infusion Rn information

See Jacksonville, FL salary details

$10

$42

$76

How much do weekend infusion rn jobs pay per hour?

As of Jul 30, 2026, the average hourly pay for weekend infusion rn in Jacksonville, FL is $42.59, according to ZipRecruiter salary data. Most workers in this role earn between $33.65 and $46.54 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion Rn position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN job?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the most commonly searched types of Infusion Rn jobs in Jacksonville, FL? The most popular types of Infusion Rn jobs in Jacksonville, FL are:
What are popular job titles related to Weekend Infusion Rn jobs in Jacksonville, FL? For Weekend Infusion Rn jobs in Jacksonville, FL, the most frequently searched job titles are:
What cities near Jacksonville, FL are hiring for Weekend Infusion Rn jobs? Cities near Jacksonville, FL with the most Weekend Infusion Rn job openings:
Infographic showing various Weekend Infusion Rn job openings in Jacksonville, FL as of July 2026, with employment types broken down into 4% As Needed, 55% Full Time, 37% Part Time, and 4% Contract. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $88,586 per year, or $42.6 per hour.

Home Infusion RN - Up to $50/hr + Mileage | Flexible Schedule

Amotec Health

Fernandina Beach, FL • On-site

$50/hr

Other

Re-posted 22 days ago


Job description

Home Infusion RN - Up to $50/hr + Mileage | Flexible Schedule
Location: Jacksonville, FL
Compensation: up to $50/hr+ Mileage
Compassionate Care. Professional Expertise.
Amotec Health partners with specialty pharmacies nationwide to provide in-home infusion therapy for patients. We're seeking experienced Registered Nurses (RNs) experienced in home infusion therapy or RN's experienced in oncology nursing with prior infusion experience with strong IV skills to deliver life-changing care in the comfort of patients' homes.
This opportunity is ideal for nurses who thrive working independently, enjoy building patient relationships, and want the support of a national clinical team behind them.
About the Role
As a Home Infusion RN, you will administer advanced therapies, monitor patient response, and educate patients and caregivers on treatment plans and self-administration. Cases vary in length and complexity, and you'll have flexibility in accepting assignments within your local service area.
Therapies We Support
  • Immunotherapies: IVIG & SCIG
  • Clinical Trials
  • Alpha-1 Therapy
  • Hemophilia Therapy
  • Enzyme Replacement Therapy
  • Biologic Therapy
  • Inotropic Therapy
  • HIV Therapy
  • Antibiotic Therapy
  • Steroid Therapy
  • Patient & caregiver teaching/training for various medications
Key Responsibilities
  • Safely administer IV medications, infusions, and specialty therapies
  • Perform comprehensive patient assessments and monitor before, during, and after infusion
  • Access and manage vascular devices (PICC, midline, port, peripheral)
  • Educate and train patients and caregivers on therapy, equipment, and symptom recognition
  • Document all care accurately and in compliance with policies
  • Communicate effectively with pharmacy, clinicians, and Amotec Nurse Staffing team
  • Travel locally to patient homes, infusion suites, or physician offices as assigned
What We're Looking For
  • Active, unrestricted RN license in the state(s) of practice
  • Current CPR/BLS certification (required)
  • Valid driver's license and reliable transportation
  • 4-5 years of nursing experience preferred, including at least 1 year in home infusion, acute care, or a specialty IV setting within the last 24 months
  • Demonstrated proficiency with IV insertion, port access, and infusion pumps
  • Strong documentation and organizational skills
  • Excellent patient communication and education abilities
  • Willingness to travel up to a 100-mile radius as needed
Why Work with Amotec Nurse Staffing?
For more than 20 years, Amotec Health has built a reputation on integrity, quality, and care. Our Nurse Staffing division is dedicated to supporting infusion nurses with the resources, flexibility, and respect they deserve.
  • Up to $50/hour pay plus drive time or mileage reimbursement
  • Weekly pay with direct deposit
  • Flexible scheduling - part-time or full-time opportunities available
  • Insurance options offered
  • 24/7 support from clinical managers and coordinators
  • Opportunities to expand into new therapies with paid training
Hours & Scheduling
  • Typical assignment length: 2 to 8 hours per case (on average)
  • You may have multiple cases in a day, depending on geography
  • Travel time between cases is compensated (most cases)
  • Mileage reimbursement provided (or gas/travel stipend)
  • Schedule flexibility: you'll be assigned a service window, with opportunity to accept or decline based on availability

Apply today to join Amotec Health and make a difference by bringing specialized infusion care to patients where they need it most.