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Weekend Infusion Rn Jobs in Tampa, FL (NOW HIRING)

First Day Homecare

Infusion Registered Nurse

Tampa, FL · On-site

Current license as a Registered Nurse in the state(s) of practice. * Proficient in various infusion and injectable medications, including peripheral intravenous (IV) starts and accessing infusion ...

First Day Homecare

Infusion Registered Nurse

Tampa, FL · On-site

Current license as a Registered Nurse in the state(s) of practice. * Proficient in various infusion and injectable medications, including peripheral intravenous (IV) starts and accessing infusion ...

Sage Infusion

Infusion Care RN (PRN)

Clearwater Beach, FL · On-site

$34.25 - $45.25/hr

Clean and sanitize infusion rooms and equipment between patients and at end of day. * Other duties as delegated by the provider. Licensed/Experience: * Florida Registered Nurse license * Maintains ...

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All JobsInfusion Rn JobsWeekend Infusion Rn JobsWeekend Infusion Rn Jobs in Tampa, FL

Weekend Infusion Rn information

See Tampa, FL salary details

$10

$43

$78

How much do weekend infusion rn jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for weekend infusion rn in Tampa, FL is $43.44, according to ZipRecruiter salary data. Most workers in this role earn between $34.28 and $47.50 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies based on location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Tampa, FL?

The most popular types of Infusion Rn jobs in Tampa, FL are:

What are popular job titles related to Weekend Infusion Rn jobs in Tampa, FL?

For Weekend Infusion Rn jobs in Tampa, FL, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in Tampa, FL look for?

The top searched job categories for Weekend Infusion Rn jobs in Tampa, FL are:

What cities near Tampa, FL are hiring for Weekend Infusion Rn jobs?

Cities near Tampa, FL with the most Weekend Infusion Rn job openings:

Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Tampa, FL as of August 2026, with employment types broken down into 11% As Needed, 45% Full Time, and 44% Part Time. Highlights an 100% In-person job distribution, with an average salary of $90,350 per year, or $43.4 per hour.

IV/Infusion Registered Nurse (RN) - PRN - St. Petersburg, FL

NurseCore

Saint Petersburg, FL • On-site

$40 - $45/hr

Part-time

Posted 7 days ago

Job description

Now Hiring: IV/Infusion Registered Nurse (RN) – PRN 
Location: St. Petersburg, FL and Surrounding Areas
Schedule: PRN / Per Diem | Days, Evenings, & Weekends
Pay range $40.00-$45.00 per hour 
***Pay is based on the client assignment, level of care, and specific clinical needs.
NurseCore is seeking a skilled and experienced Registered Nurse (RN) to provide IV and infusion therapy services in the home setting. The ideal candidate is dependable, proficient in IV insertion and infusion therapy, and confident in monitoring patients before, during, and after treatment while providing safe, high-quality care.

We Offer:

  • Competitive Pay Rates
  • Health benefits available after 6 months of employment for team members who consistently work 30 or more hours per week.
  • Daily/Weekly Pay
  • 24/7 Access to friendly staff
  • Direct Deposit
  • Bonus Opportunities
  • No 1099 Tax Filing-W2 makes a difference! You are an employee of NurseCore.

Responsibilities -

  • Initiate peripheral IV access, including IV insertion, as ordered
  • Assess and select appropriate peripheral IV insertion sites
  • Administer prescribed IV medications, fluids, and infusion therapies
  • Access, manage, and maintain PICC lines, central lines, and implanted ports as applicable to the assignment
  • Perform central line/PICC dressing changes and site care using sterile technique, as ordered
  • Flush and maintain vascular access devices according to physician orders and agency protocols
  • Assess patients before, during, and after infusion therapy
  • Monitor vital signs and patient response throughout treatment
  • Assess IV and vascular access sites for infiltration, phlebitis, infection, occlusion, or other complications
  • Recognize and respond appropriately to adverse reactions and infusion-related complications
  • Discontinue peripheral IV access as ordered or appropriate to the plan of care
  • Maintain proper infection control, aseptic, and sterile techniques
  • Provide patient and caregiver education regarding infusion therapy and vascular access care
  • Accurately document assessments, treatments, medications, and patient responses
  • Communicate changes in the patient's condition to the appropriate clinical team
  • Follow physician orders, the established plan of care, and applicable agency policies and procedures

Qualifications:

  • Current, unrestricted Registered Nurse (RN) license in the State of Florida
  • Minimum of one (1) year of nursing experience in a supervised setting within the past three (3) years
  • IV/infusion nursing experience required
  • Proficient in peripheral IV insertion, including the ability to independently establish IV access
  • Experience with PICC lines, central lines, and implanted ports preferred
  • Knowledge of vascular access device management, sterile technique, and infection prevention
  • Ability to recognize and respond appropriately to infusion-related reactions and complications
  • Current CPR/BLS certification
  • Successful completion of required Relias competency and skills assessments
  • Valid AHCA Level 2 Background Screening or ability to obtain
  • Negative TB screening within the past 1 year or chest X-ray within the past 5 years
  • Home infusion and/or home care experience preferred
  • Strong patient assessment, communication, and clinical documentation skills
  • Ability to work independently and provide safe, high-quality care in the home setting
  • Reliable transportation
  • Must meet all applicable state and federal requirements

Equal Opportunity Statement - We are proud to be an equal opportunity employer and are committed to building a team that reflects the diverse communities we serve. We welcome nurses of all backgrounds, identities, and experiences. Inclusion is at the heart of the care we provide.
Applicants must complete a Level 2 
background screening through the Florida 
Care Provider Background Screening 
Clearinghouse. NurseCore will coordinate this 
with you. For information about the 
background screening process, disqualifying 
offenses, and screening requirements, please 
visit the Florida Care Provider Background 
Screening Clearinghouse resource:
#INDFL

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