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Weekend Infusion Rn Jobs in Irvine, CA (NOW HIRING)

Moffitt

PRN CLINICAL RSCH INFUSION RN

Long Beach, CA · On-site

$42.25/hr

The Clinical Research Unit (CRU) is currently looking for a full timeClinical Research Infusion RN Ifor theirMagnolia location. The CRU at Moffitt supports clinical investigational research by ...

Soleo Health Inc

Infusion Nurse

Huntington Beach, CA · On-site

$42 - $52/hr

... weekends as needed, 40 hours per week * Must be able to participate in an on-call rotation * Must ... Must be licensed as an RN in the state of California Requirements * RN Degree, BSN Preferred

Soleo Health Inc

Infusion Nurse

Huntington Beach, CA · On-site

$42 - $52/hr

... weekends as needed, 40 hours per week * Must be able to participate in an on-call rotation * Must ... Must be licensed as an RN in the state of California Requirements: * RN Degree, BSN Preferred

Soleo Health, Inc.

Infusion Nurse

Huntington Beach, CA · On-site

$42 - $52/hr

... weekends as needed, 40 hours per week * Must be able to participate in an on-call rotation * Must ... Must be licensed as an RN in the state of California Requirements * RN Degree, BSN Preferred

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Weekend Infusion Rn information

See Irvine, CA salary details

$12

$49

$88

How much do weekend infusion rn jobs pay per hour?

As of Aug 6, 2026, the average hourly pay for weekend infusion rn in Irvine, CA is $49.34, according to ZipRecruiter salary data. Most workers in this role earn between $38.94 and $53.94 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.
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Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $102,623 per year, or $49.3 per hour.

Experienced IVIG Registered Nurse RN Per Diem

A&G Infusion Nursing Services Inc

Mission Viejo, CA • On-site

Other

Re-posted 26 days ago

Job description

Job Overview:

We are seeking an experienced and compassionate IVIG Infusion RN to provide high-quality, in-home infusion therapy services. The ideal candidate will deliver safe, efficient, and patient-centered care while supporting patients with chronic conditions requiring IVIG and other specialty infusions.

Key Responsibilities:

Administer IVIG, antibiotics, TPN, and other specialty medications in patients’ homes.

Insert and manage peripheral IVs, PICC lines, port-a-caths, and other central lines.

Perform blood draws and monitor patient response during infusion therapy.

Provide patient education on self-administration, medication management, and infusion safety.

Collaborate with the healthcare team to develop and follow individualized care plans.

Maintain accurate and timely documentation of nursing interventions and patient progress.

Qualifications:

Active RN license in CA.

Minimum 1 year of experience in infusion therapy, including IVIG administration.

Proficiency in peripheral IV insertion, central line management, and infusion protocols.

Strong clinical assessment and patient education skills.

Reliable vehicle and valid driver’s license required.

Excellent communication and interpersonal skills.

Work Location: On the road

Employment Type: Contract, Per diem

This is a remote position.

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