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Weekend Infusion Rn Jobs in Irvine, CA (NOW HIRING)

DPS HEALTHCARE

Home Infusion RN

Walnut, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Claremont, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

La Verne, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Corona, CA · On-site

$80 - $100/hr

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Diamond Bar, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Corona, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Pomona, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Corona, CA · On-site

$80 - $100/hr

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Corona, CA · On-site

$80 - $100/hr

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Chino, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Riverside, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

San Dimas, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

DPS HEALTHCARE

Home Infusion RN

Chino Hills, CA · On-site

DPS Healthcare is looking for a dedicated and compassionate Home Infusion RN to join our growing team in Inland Empire, CA. In this role, you'll bring expert clinical care directly to patients in the ...

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Showing results 21-40

All JobsInfusion Rn JobsWeekend Infusion Rn JobsWeekend Infusion Rn Jobs in Irvine, CA

Weekend Infusion Rn information

See Irvine, CA salary details

$12

$49

$88

How much do weekend infusion rn jobs pay per hour?

As of Aug 6, 2026, the average hourly pay for weekend infusion rn in Irvine, CA is $49.34, according to ZipRecruiter salary data. Most workers in this role earn between $38.94 and $53.94 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.
What are the most commonly searched types of Infusion Rn jobs in Irvine, CA? The most popular types of Infusion Rn jobs in Irvine, CA are:
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What job categories do people searching Weekend Infusion Rn jobs in Irvine, CA look for? The top searched job categories for Weekend Infusion Rn jobs in Irvine, CA are:
What cities near Irvine, CA are hiring for Weekend Infusion Rn jobs? Cities near Irvine, CA with the most Weekend Infusion Rn job openings:
Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $102,623 per year, or $49.3 per hour.

Registered Nurse for Home Infusion Patients

Clinivoy LLC

Santa Ana, CA

$50 - $65/hr

Part-time

Re-posted 19 days ago

Job description

Home Infusion Registered Nurse (RN)

Part-Time

Salary Range: $55.00-$65.00 per hour

About Clinivoy Infusion Centers

Clinivoy Infusion Centers is a referral-based infusion provider serving patients throughout California and Arizona. In addition to our state-of-the-art infusion centers, we provide high-quality home infusion services, allowing patients to receive specialized therapies in the comfort of their own homes.

Our mission is to deliver exceptional infusion therapy through compassionate, patient-centered care while maintaining the highest standards of clinical excellence. As our organization continues to grow, we are seeking experienced and compassionate Home Infusion Registered Nurses to join our team and provide in-home infusion services throughout California.

Position Summary

The Home Infusion Registered Nurse is responsible for delivering safe, high-quality infusion therapy in patients' homes. This role requires excellent clinical judgment, strong IV skills, independent decision-making, and exceptional patient education. The RN works collaboratively with physicians, pharmacists, and the clinical team to ensure the highest level of patient care while maintaining compliance with all regulatory and company standards.

Education & Qualifications
  • Graduate of an accredited School of Nursing
  • Associate Degree in Nursing required; Bachelor of Science in Nursing (BSN) preferred
  • Minimum of 3 years of recent RN experience in ICU, ER, Critical Care, Oncology, Infusion, or a similar acute care setting
  • Previous home infusion or infusion nursing experience preferred (training available for the right candidate)
  • Current and unrestricted California Registered Nurse license
  • Current American Heart Association BLS certification (ACLS preferred)
  • Valid driver's license, reliable transportation, and current auto insurance
Skills & Abilities
  • Excellent peripheral IV insertion and central line access skills
  • Strong assessment and critical thinking abilities
  • Ability to work independently in a home setting
  • Experience with Electronic Medical Records (EMR)
  • Computer proficiency in Microsoft Word, Outlook, and Excel
  • Strong verbal and written communication skills
  • Excellent organizational and time-management skills
  • Ability to build trusting relationships with patients and caregivers
Essential Responsibilities
  • Travel to patients' homes to administer prescribed infusion therapies and injectable medications.
  • Perform comprehensive nursing assessments before, during, and after each infusion.
  • Establish peripheral IV access and access/maintain central venous access devices, including PICC lines and implanted ports.
  • Monitor patients throughout treatment and respond appropriately to adverse reactions or emergencies.
  • Educate patients and caregivers regarding medications, infusion procedures, potential side effects, and catheter care.
  • Accurately document all assessments, treatments, patient responses, and education in the electronic medical record.
  • Collaborate with physicians, pharmacists, and the clinical team to coordinate patient care.
  • Maintain infusion supplies and ensure proper handling, storage, and disposal of medications and medical waste.
  • Follow all infection control, OSHA, HIPAA, and company policies and procedures.
  • Provide compassionate, patient-focused care while promoting safety and clinical excellence.
  • Participate in quality improvement initiatives and maintain all required clinical competencies.
Travel Requirements
  • Frequent local travel to patient homes throughout assigned territories.
  • Mileage and approved business expenses are reimbursed.
  • Reliable transportation is required.
Compensation & Benefits

The hourly pay range for this position is $55.00-$65.00 per hour, depending on experience, clinical expertise, geographic location, and overall qualifications.

In addition to competitive pay, Clinivoy offers a comprehensive benefits package for eligible employees and opportunities for professional growth within our expanding infusion services.

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