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Weekend Infusion Rn Jobs in Irvine, CA (NOW HIRING)

Moffitt

CLINICAL RSCH INFUSION RN I

Long Beach, CA · On-site

$35.05 - $52.56/hr

The Clinical Research Unit (CRU) is currently looking for a full-timeClinical Research Infusion RN Ifor theirMagnolia location. The CRU at Moffitt supports clinical investigational research by ...

Moffitt

PRN CLINICAL RSCH INFUSION RN

Long Beach, CA · On-site

$42.25/hr

The Clinical Research Unit (CRU) is currently looking for a full timeClinical Research Infusion RN Ifor theirMagnolia location. The CRU at Moffitt supports clinical investigational research by ...

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Weekend Infusion Rn information

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$12

$49

$88

How much do weekend infusion rn jobs pay per hour?

As of Jul 15, 2026, the average hourly pay for weekend infusion rn in Irvine, CA is $49.34, according to ZipRecruiter salary data. Most workers in this role earn between $38.94 and $53.94 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion Rn position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN job?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the most commonly searched types of Infusion Rn jobs in Irvine, CA? The most popular types of Infusion Rn jobs in Irvine, CA are:
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What cities near Irvine, CA are hiring for Weekend Infusion Rn jobs? Cities near Irvine, CA with the most Weekend Infusion Rn job openings:
Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Irvine, CA as of July 2026, with employment types broken down into 3% As Needed, 76% Full Time, 16% Part Time, and 5% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $102,623 per year, or $49.3 per hour.
Infusion RN - Cancer Center - Full Time - Days 10hr QVH

Infusion RN - Cancer Center - Full Time - Days 10hr QVH

Emanate Health

West Covina, CA • On-site

$55.64 - $85.05/hr

Full-time

Posted 21 days ago

Emanate Health rating

7.1

Company rating: 7.1 out of 10

Based on 28 frontline employees who took The Breakroom Quiz

Job description

Current Emanate Health Employees - Please log into your Workday account to apply
Everyone at Emanate Health plays a vital role in the care we deliver. No matter what department you belong to, the work you do at Emanate Health affects lives. When you join Emanate Health, you become part of a team that works together to strengthen our communities and grow as individuals.
On Glassdoor's list of "Best Places to Work" in 2021, Emanate Health was named the #1 ranked health care system in the United States, and the #19 ranked company in the country.
Job Summary
Provides assessment and nursing intervention in all areas of Infusion Therapy when requested by physicians and/or clinical trial protocols in the outpatient setting. Perform the nursing process through individualized assessment, planning, implementation, evaluation, and documentation of safe, therapeutic, efficient, and quality care for patients consistent with the unit's standard of care. This includes chemotherapy, immunotherapy, IV therapy, and blood transfusions. Treatment methods include intravenous, subcutaneous, and injections. The infusion RN must demonstrate competency in accessing porta-caths and PICC lines as well as peripheral venous access and case management intervention. The RN is responsible for case management and care coordination across all cancer care providers and the continuum of care. The Infusion RN will coordinate patient care and implement patient specific treatment plans ordered by physicians. Provides effective education, educational resources, and support to patients and their families. Utilizes nursing skills to determine the biophysical, psychosocial, environmental, self-care and educational needs of the patient/family/significant other and work with the patients entire care team to advocate on the patient's behalf. Contributes to the educational process for patients, staff and self. Promotes clinical effectiveness, efficient use of resources, and quality care in practice setting.
Job Requirements
a. Minimum Education Requirement :
BSN preferred.
b. Minimum Experience Requirement :
Two years of chemotherapy administration experience working as an outpatient infusion RN, in a clinic, physician office, or hospital setting. Oncology Ambulatory Infusion Center experience preferred. Must have excellent attention to detail, strong communication skills, and excellent customer service and service recovery skills.
c. Minimum License Requirement :
Current California RN license. BLS and ACLS required. ONS Chemotherapy and Biotherapy provider card required. OCN certification preferred. Ongoing education of 12 cancer related continuing nursing education hours annually.
Delivering world-class health care one patient at a time.
Pay Range:
$55.64 - $85.05

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