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Weekend Infusion Rn Jobs in California (NOW HIRING)

Infusion Registered Nurse | California Seeking an experienced Infusion RN with an active California ... Enjoy a Monday-Friday, 5x8 schedule with no weekends or on-call, and only rare floating to nearby ...

Infusion Registered Nurse | California | August 17, 2026 - Ongoing | Seeking an experienced ... Enjoy a Monday-Friday, 5x8 schedule with no weekends or on-call , and only rare floating to nearby ...

Infusion * Discipline: RN * Start Date: 09/14/2026 * Duration: 13 weeks * 40 hours per week * Shift: 10 hours, days * Employment Type: Travel As an RN Infusion/PICC Nurse, you will provide ...

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Weekend Infusion Rn information

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How much do weekend infusion rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend infusion rn in California is $45.36, according to ZipRecruiter salary data. Most workers in this role earn between $35.82 and $49.57 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies based on location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in California?

The most popular types of Infusion Rn jobs in California are:

What cities in California are hiring for Weekend Infusion Rn jobs?

Cities in California with the most Weekend Infusion Rn job openings:

Infographic showing various Weekend Infusion Rn job openings in California as of August 2026, with employment types broken down into 1% As Needed, 74% Full Time, 21% Part Time, 3% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $94,354 per year, or $45.4 per hour.

RN - Outpatient Infusion / Chemotherapy

FutureSoft Consulting Inc

Salinas, CA • On-site

Contractor

Posted 7 days ago


Job description

Job Summary

We are seeking an experienced Outpatient Infusion Registered Nurse (RN) for a 13-week travel assignment in Salinas, California.

This position is ideal for an RN with recent outpatient chemotherapy and infusion experience who is comfortable administering chemotherapy, immunotherapy, biologic therapies, and other infusion medications in an outpatient setting.

The RN will provide safe, compassionate, and evidence-based care to patients receiving scheduled infusion treatments. Candidates must have an active California RN license, current BLS certification, and an active ONS Chemotherapy/Immunotherapy certification.

Recent Epic experience and hands-on outpatient infusion experience are important requirements for this position.

Key Responsibilities

        Provide direct nursing care to patients receiving outpatient infusion therapy.

        Administer chemotherapy, immunotherapy, biologic agents, hydration therapy, blood products, and other prescribed infusions within scope of practice.

        Verify treatment plans, medication orders, patient identity, laboratory results, allergies, and treatment parameters before administration.

        Perform comprehensive pre-treatment patient assessments.

        Monitor patients throughout infusion therapy for adverse reactions, complications, and changes in clinical condition.

        Recognize and respond promptly to chemotherapy or infusion-related reactions.

        Initiate emergency interventions when necessary.

        Perform peripheral IV insertion and manage vascular access devices.

        Access, assess, maintain, and de-access implanted ports according to facility policy.

        Manage PICC lines and other central venous access devices as appropriate.

        Administer medications safely according to provider orders and established oncology protocols.

        Provide patient and family education regarding treatment plans, medications, side effects, symptom management, and when to seek medical attention.

        Coordinate care with oncologists, pharmacists, advanced practice providers, laboratory staff, and other members of the healthcare team.

        Review laboratory values and treatment parameters before administering therapy.

        Maintain accurate and timely documentation using Epic.

        Follow chemotherapy safety standards, hazardous-drug handling requirements, infection-control procedures, and facility policies.

        Support continuity of care through clear communication and clinical handoffs.

        Float within similar departments or related clinical areas when needed and appropriately trained.

Required Qualifications

Candidates must have:

        Active California Registered Nurse (RN) license

        Graduate of an accredited nursing program

        Current BLS / Healthcare Provider certification through the American Heart Association

        Current ONS Chemotherapy/Immunotherapy certification

        Recent outpatient chemotherapy and infusion nursing experience

        Minimum 6-12 months of recent relevant experience within the past year

        Experience administering chemotherapy and infusion therapies in an outpatient environment

        Recent hands-on Epic experience

        Strong knowledge of chemotherapy safety and infusion nursing practices

Required Clinical Experience

Candidates should be comfortable with:

        Outpatient chemotherapy administration

        Immunotherapy administration

        Oncology infusion nursing

        Medication and treatment-plan verification

        Peripheral IV insertion

        Implanted port access

        Central line care

        PICC line management

        Blood product administration

        Hydration therapy

        Biologic infusions

        Patient monitoring during treatment

        Recognition and management of infusion reactions

        Emergency response

        Patient education

        Oncology symptom management

Preferred Qualifications

        Bachelor of Science in Nursing (BSN)

        At least 1 year of RN experience in outpatient infusion, oncology, or a closely related specialty

        Previous travel nursing experience

        Experience in a high-volume outpatient infusion center

        Oncology nursing experience

        Strong vascular access skills

        Experience working with multidisciplinary oncology teams

        Willingness and ability to float within a related clinical cluster when needed

Key Skills

Successful candidates should demonstrate strong competency in:

        Chemotherapy administration

        Immunotherapy administration

        Infusion therapy

        Oncology nursing

        IV medication administration

        Peripheral IV placement

        Port access and maintenance

        Central venous catheter care

        PICC line care

        Infusion reaction management

        Patient assessment

        Medication safety

        Clinical documentation

        Epic

        Patient and family education

        Emergency response

        Interdisciplinary communication

Schedule Requirements

        Day Shift

        Four 10-hour shifts per week

        40 hours per week

        Department operates Monday through Friday, approximately 7:00 AM-5:30 PM

        Department is closed on weekends

        Exact shift times may vary within department operating hours.

        Flexibility to float within similar or related departments is highly desirable.

Ideal Candidate

The ideal candidate is an experienced Outpatient Infusion RN or Oncology Infusion RN who can safely and independently manage patients receiving chemotherapy and other complex infusion treatments.

You should have strong assessment skills, excellent attention to medication safety, confidence managing infusion reactions, and the ability to educate and support patients throughout their treatment.

This opportunity may be a strong fit for professionals currently working as an:

        Outpatient Infusion RN

        Oncology Infusion RN

        Chemotherapy RN

        Infusion Center RN

        Oncology RN

        Ambulatory Infusion RN

        Hematology/Oncology RN

        Chemo Infusion Nurse

Equal Opportunity

We are an equal opportunity employer and consider qualified applicants based on experience, education, licensure, certifications, clinical skills, and the requirements of the position.