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Vp Technical Program Management Jobs (NOW HIRING)

VP, Technical Operations

Waltham, MA ยท On-site

$291K - $359K/yr

Lead and develop Technical Operations and CMC Program Management; integrate/prioritize/execute Drug ... for a VP-level role. * Extensive small-molecule development/manufacturing experience; deep Drug ...

Vice President, PMO Rapid7 is seeking a VP, PMO to lead the strategic alignment, program ... This role focuses on optimizing technical roadmap delivery, managing engineering capacity ...

$95K - $123K/yr

VP - Technical Program Manager - Autonomous Alpha Generation Platform New York, NY, United States ... Drive end-to-end project management and program execution for the central platform ...

Vice President, Technical Services

Twin Falls, ID ยท On-site

$165K - $213K/yr

Lead, mentor, and develop engineering managers and frontline technical staff; build bench strength ... Establish a best-in-class Reliability-Centered Maintenance (RCM) program; drive the transition from ...

Vice President, Technical Services

Twin Falls, ID ยท On-site

$165K - $213K/yr

Lead, mentor, and develop engineering managers and frontline technical staff; build bench strength ... Establish a best-in-class Reliability-Centered Maintenance (RCM) program; drive the transition from ...

Sr Technical Program Manager

Santa Rosa, CA ยท On-site

$90 - $100/hr

... VP and leadership team to drive annual planning processes, operating reviews, budget management ... technical program management, R&D operations, business operations, engineering management, or ...

The Vice President of Program Management serves as the cross-functional integrator and ... Define program intake and scoping processes that incorporate feasibility assessments, technical ...

Principal Technical Program Manager, Alexa

Sunnyvale, CA ยท On-site

$151K - $196K/yr

... VP/Director-level stakeholder management - Experience actively participating in and driving ... program strategies, and technical documents for senior leadership audiences - Bachelor's degree in ...

Director, Technical Program Management

Austin, TX ยท On-site

$127K - $165K/yr

We are looking for a Director of Technical Program Management to lead and grow our TPM function at ... Communicate program status, risks, and strategic dependencies to the CTO,SVP of Engineering and ...

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Vp Technical Program Management information

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$89K

$145.6K

$168.5K

How much do vp technical program management jobs pay per year?

As of Sep 15, 2026, the average yearly pay for vp technical program management in the United States is $145,648.00, according to ZipRecruiter salary data. Most workers in this role earn between $129,000.00 and $167,000.00 per year, depending on experience, location, and employer.

What are the most commonly searched types of Technical Program Management jobs?

The most popular types of Technical Program Management jobs are:

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For Vp Technical Program Management jobs, the most frequently searched job titles are:

Infographic showing various Vp Technical Program Management job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 13% Part Time, and 3% Contract. Highlights an 87% Physical, 3% Hybrid, and 10% Remote job distribution, with an average salary of $145,648 per year, or $70 per hour.

VP, Technical Operations

Waltham, MA โ€ข On-site

Scorpion Therapeutics
51 - 200 employees

$291K - $359K/yr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 16 days ago


Job description

Summary

The Vice President, Technical Operations will lead end-to-end CMC Technical Operations strategy across Drug Substance, Drug Product, and CMC Program Management, advancing small-molecule products from candidate selection and IND-enabling development through clinical development, registration, validation, commercial launch, ongoing manufacturing, and lifecycle management.

Responsibilities
  • Lead and develop Technical Operations and CMC Program Management; integrate/prioritize/execute Drug Substance, Drug Product, and cross-functional CMC activities across the product lifecycle.
  • Develop and execute phase-appropriate CMC strategies (Drug Substance, Drug Product, analytical development, manufacturing, controls, stability, validation, regulatory CMC, supply) from IND-enabling through registration, commercialization, and post-approval lifecycle management.
  • Provide technical leadership for small-molecule Drug Product development (formulation/process development, scale-up, technology transfer, characterization, control strategy, validation/PPQ, commercial readiness).
  • Provide oversight for Drug Substance development/manufacturing (scale-up, technology transfer, validation, control strategy, commercial readiness, lifecycle support).
  • Ensure CMC Program Management across the portfolio (deliverables, dependencies, critical paths, risks, resources, budgets, governance, decisions).
  • Oversee CDMOs/external manufacturing partners for development, validation, and clinical/commercial manufacturing.
  • Lead commercial manufacturing and lifecycle management (investigations, CAPAs, change controls, improvements, site transfers, continued process verification, supply continuity).
  • Partner with Supply Chain, Regulatory Affairs, Quality, and Program leadership to meet FDA/ICH/global regulatory and cGMP expectations.
  • Represent Technical Operations in cross-functional teams, executive governance, due diligence, portfolio planning, and risk management.
  • Manage resources, operating plans, budgets, and portfolio priorities.
Qualifications
  • MS/Ph.D. in Pharmaceutics/Pharmaceutical Sciences/Chemical Engineering/Chemistry (or related) with progressive pharmaceutical industry experience for a VP-level role.
  • Extensive small-molecule development/manufacturing experience; deep Drug Product expertise (formulation/process development, scale-up, technology transfer, characterization, control strategy, validation/PPQ, regulatory approval, commercial launch, ongoing manufacturing), including leading PPQ/commercial validation at external sites.
  • Broad Drug Substance technical knowledge to lead and challenge an experienced organization.
  • Demonstrated end-to-end CMC strategy development and integration across Drug Substance, Drug Product, analytical, regulatory, quality, manufacturing, and supply.
  • Strong CMC program/portfolio management (risks, dependencies, resources, budgets, timelines, governance, executive decision support).
  • Significant CDMO/external manufacturing partner management experience.
  • Strong cGMP and FDA/ICH/global regulatory knowledge; experience supporting INDs, NDAs, and post-approval submissions.
  • Ability to lead multidisciplinary technical teams and influence senior stakeholders.
  • Small-molecule Drug Product development across multiple dosage forms (oral solids and liquids).
  • Commercial lifecycle management and global manufacturing network experience (post-approval changes, site transfers, optimization, supply risk, international submissions).
  • Technical due diligence experience for licensing/acquisitions/partnerships.
Compensation and Benefits
  • Targeted Base Salary: $291,349 USD - $359,902 USD.
  • Additional benefits include health care, vision, dental, retirement, PTO, etc.
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