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Vice President Performance Optimization Jobs in Wakefield, MA

Blue Castle Agency

Executive Vice President

Boston, MA

$180K - $225K/yr

EXECUTIVE VICE PRESIDENT Our client is currently seeking an Executive Vice President who will ... and performance reporting. * Adept at controlling expenses, optimizing revenue streams, and ...

Blue Castle Agency

Regional Vice President

Boston, MA · On-site

$150K - $200K/yr

REGIONAL VICE PRESIDENT Our client is currently seeking a Regional Vice President who will oversee ... and performance reporting. * Adept at controlling expenses, optimizing revenue streams, and ...

1872 Consulting

VP of Finance

Boston, MA · On-site

VP of Finance In close collaboration with system finance leaders, the President/CEO and senior ... S/he continuously assesses and evaluates the financial performance of the organization with regards ...

1872 Consulting

VP of Finance

Boston, MA · On-site

VP of Finance In close collaboration with system finance leaders, the President/CEO and senior ... S/he continuously assesses and evaluates the financial performance of the organization with regards ...

SS&C

VP Digital Marketing

Braintree, MA · Hybrid

Job Title: VP of Digital Marketing Locations : New York, NY or Boston, MA | Hybrid Get To Know Us ... Performance, Insight & Optimization * Partner with Marketing Technology & Operationsleader ...

GXO Logistics

Vice President, Transportation

Boston, MA · On-site

The Vice President, Transportation is responsible for leading the strategic direction, operational ... Deliver financial performance through revenue growth, cost optimization, productivity improvements ...

New

Vinfen

VP of Nursing

Cambridge, MA

Utilizes staff appropriately with the goal of optimizing effort and achieving clinical, operational ... Evaluates performance of nursing staff in conjunction with DOSs/VPs. VP Nursing MA Admin * Reviews ...

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Vice President Performance Optimization information

See Wakefield, MA salary details

$45.9K

$166.1K

$292.5K

How much do vice president performance optimization jobs pay per year?

As of Aug 12, 2026, the average yearly pay for vice president performance optimization in Wakefield, MA is $166,073.00, according to ZipRecruiter salary data. Most workers in this role earn between $121,200.00 and $200,300.00 per year, depending on experience, location, and employer.

What does a vice president performance optimization do?

A Vice President of Performance Optimization is responsible for identifying and implementing strategies that improve the efficiency and effectiveness of an organization's operations. This executive role involves analyzing business processes, setting performance metrics, and working with various departments to ensure goals are met. The VP of Performance Optimization typically oversees teams, leads change management initiatives, and uses data-driven insights to drive continuous improvement. Their ultimate goal is to enhance productivity, reduce costs, and maximize overall business performance.

What are some common challenges faced by a vice president performance optimization when implementing organization-wide improvement initiatives?

A Vice President of Performance Optimization often encounters challenges such as resistance to change from various departments, aligning cross-functional teams with new performance metrics, and ensuring consistent data quality for accurate analysis. Successfully implementing improvement initiatives requires strong communication skills to gain buy-in from stakeholders and the ability to translate complex data into actionable strategies. Building a culture of continuous improvement and fostering collaboration across departments are also key to overcoming these obstacles and driving sustainable results.

What are the key skills and qualifications needed to thrive as a vice president performance optimization?

To excel as a Vice President of Performance Optimization, you need expertise in business strategy, data analytics, process improvement, and a proven track record in leadership roles, typically supported by an advanced degree in business or a related field. Familiarity with performance management systems, business intelligence tools, and methodologies like Six Sigma or Lean is often required. Exceptional communication, change management, and critical thinking skills help drive cross-functional collaboration and inspire teams. These competencies are vital for identifying operational inefficiencies, implementing effective solutions, and aligning organizational performance with strategic goals.

What is the difference between Vice President Performance Optimization vs Director of Performance Optimization?

AspectVice President Performance OptimizationDirector of Performance Optimization
CredentialsBachelor's/Master's in Business, Analytics, or related; extensive experienceBachelor's/Master's in Business, Analytics, or related; significant experience
Work EnvironmentExecutive leadership, strategic planning, cross-department collaborationManagement of teams, project oversight, implementing performance strategies
Employer & Industry UsageCorporate, large enterprises, consulting firmsCorporate, mid to large organizations, industry-specific sectors

The Vice President Performance Optimization focuses on high-level strategic initiatives and leadership, overseeing performance across the organization. The Director of Performance Optimization manages teams and executes strategies at a departmental level. Both roles require similar credentials but differ in scope and responsibility, with the VP being more strategic and the Director more operational.

What cities near Wakefield, MA are hiring for Vice President Performance Optimization jobs? Cities near Wakefield, MA with the most Vice President Performance Optimization job openings:
Vice President Performance Optimization jobs near you

Vice President, Global Trial Optimization

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$301K - $408K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

This job post has expired today. Applications are no longer accepted.

Job description

Overview
The Vice President, Global Trial Optimization leads strategic feasibility, protocol optimization, and scenario planning to inform clinical trial design that aligns the science with data driven, efficient delivery plans. Also, the Vice President, Global Trial Optimization oversees patient recruitment and retention strategies and patient and site experience which maximizes acceleration and trial efficiency. As a member of the Pipeline Delivery Leadership Team, the Vice President, Global Trial Optimization is accountable for strategic feasibility and scenario planning, protocol optimization, site identification, patient recruitment and retention, patient and site experience as well as people management.
Reporting to the SVP, Pipeline Delivery, the Vice President, Global Trial Optimization will lead a team of in support of all clinical trials in the Development portfolio.
Key Responsibilities
  • Drives a Feasibility Center of Excellence and partners with our preferred CROs to deliver data driven, accurate and optimal clinical trial scenario plans for country placement, enrollment rates and study timelines; designs and develops feasibility tools and processes
  • Leads country placement discussions at Program Leadership Team and outlines country placement recommendations for clinical trials in support of business and trial needs; represents Clinical Operations at governance forums (e.g.: DevBoard, DOC, PLT) as appropriate
  • Leads the protocol feasibility and scenario modeling and recommends optimized trial delivery strategies for country and site placement, enrollment rates, site identification and trial milestones that inform decision making at governance forums
  • Oversees clinical trial enrollment modeling and identifies the best path to clinical trial patients; models the impact of inclusion/exclusion criteria on enrollment potential and trial timelines
  • Partners with study teams and CROs to provide data driven accurate study timelines, milestone, and enrollment assumptions; leads clinical operations lock (CLOCK) reviews and partners with study team to communicate CLOCK milestones at governance forums
  • Facilitates site identification and outlines best fit site archetype
  • Accountable for predictable and consistent delivery of patient recruitment & retention strategies. Leads identification and selection of portfolio level recruitment strategies and sourcing, with a focus on reduced patient burden and diversity where appropriate
  • Provides robust estimates for the impact of patient recruitment programs on trial enrollment and cost
  • Identifies and analyzes important connections within and across therapeutic areas to optimize study planning and performance at the portfolio level

Qualifications
  • MSc, MBA, PhD or equivalent in relevant discipline strongly preferred
  • 20+ years industry experience focused on Clinical Operations, including global clinical trial conduct, feasibility, protocol optimization, patient recruitment and retention, and working with global CROs
  • 10+ year team leadership, building strong feasibility and patient recruitment teams
  • Thorough understanding of clinical trial feasibility and scenario planning; including demonstrated experience with supportive tools, technologies, Monte Carlo simulations etc. Proven experience in data analysis, data interpretation to drive informed decision making
  • A thorough understanding of the processes associated with feasibility, protocol optimization, site identification, patient recruitment and retention
  • Extensive experience in patient recruitment campaigns
  • Demonstrated ability to deliver results and achieve objectives within budget and timeline constraints. Proven experience in cost optimization and reduction
  • Extensive experience in pharmaceutical/biotechnology and extensive knowledge of drug development processes, ICH-GCP guidelines, 21 CRF Part 11, and major Health Authority regulations as they pertain to the operational aspects of clinical trials
  • Comfortable working with Senior Executive Teams
  • Well networked with industry peers
  • Strong project management skills and effective matrix leader. Able to hold teams accountable to deliverables
  • Ability to travel up to 30%
  • Thrives in highly entrepreneurial biotech environment and embraces Alnylam's culture of science, passion, and urgency
  • Clear alignment with Alnylam Core Values
    • Commitment to People
    • Fiercely Innovative
    • Purposeful Sense of Urgency
    • Open Culture
    • Passion for Excellence

U.S. Pay Range
$301,800.00 - $408,200.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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