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Upstream Process Engineer Jobs in Pennsylvania (NOW HIRING)

MSD

Sr. Spclst , OT Research Infrastructure

West Point, PA

$105K - $143K/yr

... engineering related degree. * A Master's degree is preferred. Required Experience and Skills: * 5 years of experience with upstream manufacturing systems, pilot plant automation, process automation ...

Merck & Co.

$105K - $143K/yr

... engineering related degree. - A Master's degree is preferred. - Required Experience and Skills: - 5 years of experience with upstream manufacturing systems, pilot plant automation, process automation ...

Interon IT Solutions

Appian Developer

Malvern, PA · On-site

... upstream and downstream enterprise systems. The ideal candidate should have strong hands-on ... Develop process models, interfaces, records, reports, integrations, and business rules in Appian.

CEDENT

Appian Developer

Philadelphia, PA

... upstream and downstream systems. * Developing and configuring applications using Appian ... Maintain proper documentations across application and process/design flows. * Debug, troubleshoot ...

CCI Systems, Inc.

Field Engineer

Allentown, PA · On-site

Diagnose and repair plant related issues to reduce upstream noise and forward path impairments ... Understanding the project SOW and escalation process for deviations. * Report accurate daily ...

Zeeco

Regional Sales Manager

Pittsburgh, PA

Bachelor's Degree in Engineering or a combination of work experience Experience in upstream E&P / midstream hydrocarbon processing industry Knowledge of combustion / heat transfer equipment is ...

Zeeco

Regional Sales Manager

Pittsburgh, PA · On-site

... Engineering or a combination of work experience • Experience in upstream E&P / midstream hydrocarbon processing industry • Knowledge of combustion / heat transfer equipment is preferred • ...

AK Steel

Quality Engineer

Coatesville, PA · On-site

$70K - $91K/yr

Monitorproduct and process variability and performance to standard * Meet with representatives of ... Communicate with upstream and downstream operations and non-Cleveland-Cliff'scontractors to ...

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Showing results 21-40

All JobsUpstream Process Engineer JobsUpstream Process Engineer Jobs in Pennsylvania

Upstream Process Engineer information

See Pennsylvania salary details

$49.6K

$92.2K

$142.8K

How much do upstream process engineer jobs pay per year?

As of Aug 6, 2026, the average yearly pay for upstream process engineer in Pennsylvania is $92,239.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $103,200.00 per year, depending on experience, location, and employer.

What does an upstream process engineer do?

An Upstream Process Engineer is responsible for developing, optimizing, and scaling up processes related to the early stages of biopharmaceutical manufacturing, including cell culture and fermentation. They work on improving yield, ensuring process efficiency, and maintaining regulatory compliance. Their role involves troubleshooting, process design, and collaboration with cross-functional teams to support production.

What are the key skills and qualifications needed to thrive as an upstream process engineer, and why are they important?

Upstream Process Engineers require a solid background in chemical or biochemical engineering, process design, and troubleshooting, often backed by a relevant engineering degree. Familiarity with simulation software such as Aspen Plus or HYSYS, as well as knowledge of industry standards and certifications like Six Sigma or API, is highly valued. Strong communication, problem-solving abilities, and teamwork skills help these engineers excel when coordinating across multidisciplinary teams. These competencies are crucial to ensure process efficiency, safety, and innovation in large-scale production environments.

What are the typical daily responsibilities of an upstream process engineer?

An Upstream Process Engineer typically focuses on designing, optimizing, and monitoring processes related to raw material extraction and initial conversion in industries such as oil & gas, biotechnology, or chemicals. Daily tasks might involve analyzing process data, troubleshooting equipment or process issues, implementing efficiency improvements, and ensuring compliance with safety and environmental regulations. Collaboration is a key part of the role, as you’ll work closely with operations, maintenance, quality assurance, and R&D teams to achieve production targets. Engineers also regularly participate in safety meetings, process audits, and project planning sessions to support continuous improvement. This dynamic environment offers exposure to both hands-on technical work and cross-functional project leadership.

What are popular job titles related to Upstream Process Engineer jobs in Pennsylvania? For Upstream Process Engineer jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Upstream Process Engineer jobs in Pennsylvania look for? The top searched job categories for Upstream Process Engineer jobs in Pennsylvania are:
Upstream Process Engineer jobs near you
Infographic showing various Upstream Process Engineer job openings in Pennsylvania as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 4% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $92,239 per year, or $44.3 per hour.

Process Scientist (Philadelphia, PA)

CEDENT

Philadelphia, PA

Other

Re-posted 20 days ago

Job description

Title: Process Scientist Report: CTO Location: Philadelphia, PA Position Type: Full Time, Exempt Travel: Occasional (0-10%) Position Summary This position is part of the Technology team responsible for Client technology development, process development, and assisting in transferring developed process to GMP manufacturing. A Scientist is a mid-level individual with understanding of cell/molecular biology and previous experience in either upstream or downstream biopharmaceutical processing that utilizes bioreactors. A Scientist is responsible for hands-on execution of experiments and technology transfer, as well as authoring experimental protocols, SOPs, and batch documents.

A Scientist is expected to independently complete objectives given by supervisor, serve as a role model to junior scientists, collaborate cross-functionally, and provide support with any other technology, process development, and manufacturing needs. Key Responsibilities Independently contribute to technology/process development for specific bioprocessing steps, ensuring delivery in alignment with Client strategy Support Senior/Principal Scientist with experimental design, execution and data analysis, effectively communicating technical results to management Author protocols, SOPs, and batch documents to ensure the successful transfer of technology/process development to GMP manufacturing Perform as a Subject Matter Expert on a cross-functional team to implement novel process. Work closely with suppliers and other partners to drive forward technology development initiatives Serve as a good financial steward to the Technology team at Client and help to implement budgetary adherence and financial governance Coach and train junior scientists/employees on activities and documentation related to technology development, process development.

Other related duties as assigned. Education and Experience Minimum Bachelor's degree in Biological Engineering, Biotechnology, Biology, Biochemistry, or other related field. Master's preferred.

2-3 years of industry or academic experience in combination with Bachelor's or Master's degree. Knowledge, Skills and Abilities Experience with methodologies used for upstream or downstream viral vector production in either industry or academia Experience in experimental design, execution, and data analysis Excellent communication, collaboration, and technical writing skills Innovative and creative mindset, with problem solving capabilities Proficient in Microsoft Office products. Physical Requirements Ability to lift and carry up to 30lbs Ability to sit and stand for extended periods Excellent manual dexterity and ability to perform repetitive movements with fingers/hands Other Physical Requirements: PPE and gown training will be required as this individual will be required to enter into Laboratory and Cleanroom areas.

Work Environment: Work is performed primarily onsite in Philadelphia. 50% or more of the time, this role is in the laboratory.

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About Cedent

Sourced by ZipRecruiter

CEDENT strives to attract and retain the best people and provide an environment where they can all develop professionally and build a rewarding career. As a result, we create an inclusive environment that is rich in diversity, acknowledges each individual's uniqueness and promotes respect, personal achievement and stewardship. Our clients are global and so is CEDENT. We build and maintain a global workforce that includes people from different backgrounds, with a vast range of skills and experience all united by a common culture and commitment to help our clients achieve high performance. Cultivating a diverse workforce and inclusive work environment makes business sense. Our peoples varied skills are the talent engine that powers CEDENT, enabling it in turn to deliver the innovative solutions that help our clients outperform competitors.

Industry

It services

Company size

11 - 50 Employees

Headquarters location

Plano, TX, US

Year founded

2008

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