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Upstream Process Engineer Jobs in Pennsylvania (NOW HIRING)

Upstream Processing * Downstream Processing * CIP (Clean-in-Place) Systems * PSE (Process Support ... Coordinate with engineering, operations, quality, automation, and project teams * Support deviation ...

Upstream Processing * Downstream Processing * CIP (Clean-in-Place) Systems * PSE (Process Support ... Coordinate with engineering, operations, quality, automation, and project teams * Support deviation ...

... upstream and downstream enterprise systems. The ideal candidate should have strong hands-on ... Develop process models, interfaces, records, reports, integrations, and business rules in Appian.

Automation Project Engineer

Dunbar, PA · On-site

$90K - $105K/yr

TheAutomation Project Engineer is a pivotal role focused on designing and implementing automation ... Strong understanding of HSE processes and procedures involved in Upstream and Midstream settings ...

... upstream and downstream systems. * Developing and configuring applications using Appian ... Maintain proper documentations across application and process/design flows. * Debug, troubleshoot ...

Diagnose and repair plant related issues to reduce upstream noise and forward path impairments ... Understanding the project SOW and escalation process for deviations. * Report accurate daily ...

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Upstream Process Engineer information

See Pennsylvania salary details

$49.6K

$92.2K

$142.8K

How much do upstream process engineer jobs pay per year?

As of Jul 17, 2026, the average yearly pay for upstream process engineer in Pennsylvania is $92,239.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $103,200.00 per year, depending on experience, location, and employer.

What does an Upstream Process Engineer do?

An Upstream Process Engineer is responsible for developing, optimizing, and scaling up processes related to the early stages of biopharmaceutical manufacturing, including cell culture and fermentation. They work on improving yield, ensuring process efficiency, and maintaining regulatory compliance. Their role involves troubleshooting, process design, and collaboration with cross-functional teams to support production.

What are the key skills and qualifications needed to thrive in the Upstream Process Engineer position, and why are they important?

Upstream Process Engineers require a solid background in chemical or biochemical engineering, process design, and troubleshooting, often backed by a relevant engineering degree. Familiarity with simulation software such as Aspen Plus or HYSYS, as well as knowledge of industry standards and certifications like Six Sigma or API, is highly valued. Strong communication, problem-solving abilities, and teamwork skills help these engineers excel when coordinating across multidisciplinary teams. These competencies are crucial to ensure process efficiency, safety, and innovation in large-scale production environments.

What are the typical daily responsibilities of an Upstream Process Engineer?

An Upstream Process Engineer typically focuses on designing, optimizing, and monitoring processes related to raw material extraction and initial conversion in industries such as oil & gas, biotechnology, or chemicals. Daily tasks might involve analyzing process data, troubleshooting equipment or process issues, implementing efficiency improvements, and ensuring compliance with safety and environmental regulations. Collaboration is a key part of the role, as you’ll work closely with operations, maintenance, quality assurance, and R&D teams to achieve production targets. Engineers also regularly participate in safety meetings, process audits, and project planning sessions to support continuous improvement. This dynamic environment offers exposure to both hands-on technical work and cross-functional project leadership.

What job categories do people searching Upstream Process Engineer jobs in Pennsylvania look for? The top searched job categories for Upstream Process Engineer jobs in Pennsylvania are:
Scientist II (Biological process)

Scientist II (Biological process)

Artech Information System LLC

Swiftwater, PA

Contractor

Re-posted 28 days ago


Job description

Company Description

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.

Job Description

Candidate must have hands-on experience with upstream or downstream biological processes in cGMP or cGLP areas. Candidate must be able to understand and rigorously follow laboratory procedures and protocols; maintain clear and legible records; promote a clean and safe laboratory environment. Prior experience in either biological product recovery/purification (particularly processes involving tangential flow filtration) or upstream fermentation areas is a must. Regardless of the candidate s area of prior expertise, he/she will be required to cross-train on BOTH fermentation and purification processes. Hands-on experience with operating HPLC is an added plus.


Responsibilities include (1) execution of process development laboratory studies (fermentation, purification) and maintaining thorough records in lab notebooks [80% time] and (2) assisting with protocols, development reports and datapacks [20% time].


Skills:

Hands-on biochemical laboratory operations

- Adherence to safety and cGLP procedures; use of PPE

- Basic writing and communication skills


Qualifications

BS in Life Sciences, Chemistry, Biochemistry or Chemical/biochemical Engineering Required

Additional Information

Best Regards,

Akriti Gupta

Associate Recruiter(Scientific & Clinical Division)

Artech Information Systems LLC

360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 

Office: 973.967.3409 | Fax: 973.998.2599

Connect with us on - LinkedIn | Facebook | Twitter







Artech logo

About Artech

Sourced by ZipRecruiter

Artech is a leading IT staffing and consulting company based in Morristown, NJ, US. Since its foundation in 1992, Artech has mastered in complementing human expertise with technology and business acumen to produce world-class staffing solutions. The company caters to diverse industry sectors, including financial services, healthcare, telecommunication, energy and utilities, supply chain, and retail. It provides IT consulting, project management, professional and staff augmentation, and managed staffing services. Artech's mission is to provide exceptional IT staffing services to its clients by comprehending their business needs and then crafting a customized staffing strategy. Its notable achievement includes being recognized as one of the largest IT staffing companies in the U.S, according to Staffing Industry Analysts (SIA).

Industry

Recruiting and staffing services

Company size

10,000+ Employees

Headquarters location

Morristown, NJ, US

Year founded

1992