ZipRecruiter

Log In

1

Upstream Process Development Jobs in New Hampshire

Laars Heating Systems

QUALITY ENGINEER I

Rochester, NH · On-site

$70K - $91K/yr

... D laboratory. Our focus is on new condensing boiler and heat pump water heater technology and the ... upstream process control, statistical process monitoring, and supplier capability - ensuring ...

LAARS Heating Systems Co.

QUALITY ENGINEER I

Rochester, NH · On-site

$70K - $91K/yr

... D laboratory. Our focus is on new condensing boiler and heat pump water heater technology and the ... upstream process control, statistical process monitoring, and supplier capability - ensuring ...

Peak Physical Therapy

Physical Therapist

Roxbury, NH · On-site

$85K - $100K/yr

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Apple

Linux Kernel Engineer

Durham, NH · On-site

$142K - $263K/yr

... development through production, we would like to hear from you. Preferred Qualifications Proven track record of upstream contributions to the Linux kernel project or similar upstreams. Minimum ...

Apple

Linux Kernel Engineer

Durham, NH · On-site

$142K - $263K/yr

... development through production, we would like to hear from you. Preferred Qualifications Proven track record of upstream contributions to the Linux kernel project or similar upstreams. Minimum ...

Apple

Linux Kernel Engineer

Durham, NH · On-site

$142K - $263K/yr

... development through production, we would like to hear from you. Preferred Qualifications Proven track record of upstream contributions to the Linux kernel project or similar upstreams. Minimum ...

Apple

Linux Kernel Engineer

Durham, NH · On-site

$142K - $263K/yr

... development through production, we would like to hear from you. Preferred Qualifications Proven track record of upstream contributions to the Linux kernel project or similar upstreams. Minimum ...

Apple

Linux Kernel Engineer

Durham, NH

$142K - $263K/yr

... development through production, we would like to hear from you. Preferred Qualifications Proven track record of upstream contributions to the Linux kernel project or similar upstreams. Minimum ...

next page

Showing results 1-20

All JobsUpstream Process Development JobsUpstream Process Development Jobs in New Hampshire

Upstream Process Development information

What are the key skills and qualifications needed to thrive in upstream process development?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What are common upstream process development jobs?

Common upstream process development jobs include roles such as upstream process scientist, process engineer, and bioprocess development specialist. These positions focus on optimizing cell culture, fermentation, and bioreactor processes to improve product yield and quality, often requiring knowledge of bioreactor operation, cell biology, and process scale-up. Skills in laboratory techniques, process modeling, and regulatory compliance are also important in these roles.

What is an upstream process development job?

An upstream process development job involves designing, optimizing, and scaling the early stages of biopharmaceutical production, such as cell culture and fermentation processes. Professionals in this role typically work with bioreactors, laboratory equipment, and process analytical tools to improve yield and quality of biological products. Strong knowledge of microbiology, biochemistry, and process engineering is essential, along with adherence to regulatory standards.

What are popular job titles related to Upstream Process Development jobs in New Hampshire?

For Upstream Process Development jobs in New Hampshire, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development jobs in New Hampshire look for?

The top searched job categories for Upstream Process Development jobs in New Hampshire are:

Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in New Hampshire as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 81% Full Time, 15% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution.

QUALITY ENGINEER I

Rochester, NH • On-site

Laars Heating Systems
Machinery Manufacturing • 201 - 500 employees
Learn more about Laars Heating Systemsexternal

$70K - $91K/yr

Full-time

Re-posted 27 days ago

Job description

Laars Heating Systems Company is a global leader in the boiler and water heater industry. Our products are designed and manufactured in the United States and we have earned a competitive advantage through our innovation and customer dedication. We have a talented team of Engineers, Designers, and Technicians, along with a new state-of-the-art R&D laboratory. Our focus is on new condensing boiler and heat pump water heater technology and the continued growth and success of our organization.
Laars Heating Systems is seeking a Quality Engineer 1 (QE1) who is responsible for driving measurable improvement in product quality and process performance across the boiler and water heater manufacturing operation. This role uses data analysis, sound engineering principles, and structured problem-solving methodologies (e.g., 8D, A3, DMAIC, Six Sigma) to identify and eliminate the root causes of quality issues at their source.
A central focus of this position is to maintain a proactive, prevention-based posture and culture as opposed to a reactive, inspection-dependent quality model. The QE will work to limit reliance on incoming and fabrication inspection by strengthening upstream process control, statistical process monitoring, and supplier capability - ensuring quality is built into the process rather than caught at the end of it.
This position serves as a primary point of responsibility for both customer-facing and supplier-facing quality matters, partnering closely with Manufacturing Engineering, Design Engineering, Production, Procurement, Service, suppliers, and external customers. The QE acts as a cross-functional connector - translating field issues, supplier nonconformances, and process variation into practical, sustainable corrective actions that reduce scrap, rework, and warranty costs while improving throughput, delivery reliability, and the overall customer experience.
Role Responsibilities
Quality Engineering & Process Improvement
  • Analyze quality, scrap, rework, and warranty data to identify trends, prioritize improvement opportunities, and quantify cost of poor quality (COPQ).
  • Lead and participate in root cause analysis and structured problem-solving (5-Why, Fishbone, 8D, A3) for internal nonconformances, field failures, and customer complaints.
  • Develop, implement, and maintain control plans, PFMEAs, and process control methods (SPC, gauge R&R, capability studies) to stabilize and improve manufacturing processes.
  • Partner with Manufacturing Engineering and Production teams to design and validate process improvements, error-proofing (poka-yoke), and inspection methods that prevent defects rather than detect them downstream.
  • Drive corrective and preventive action (CAPA) plans through to verified, sustained closure.

Incoming Inspection Reduction & Supplier Quality
  • Lead efforts to reduce reliance on incoming inspection by qualifying supplier processes, implementing source inspection or certified supplier programs, and validating supplier process capability.
  • Serve as the primary supplier quality contact: lead supplier corrective action requests (SCARs), supplier audits, and capability assessments.
  • Collaborate with Procurement to evaluate and develop supplier quality performance, including onboarding new suppliers and managing ongoing supplier scorecards.
  • Work with suppliers on PPAP/first article approval, process validation, and continuous improvement initiatives tied to incoming material quality.

Customer Quality
  • Act as the primary point of contact within the quality team for external customer quality concerns, field issues, and warranty trends, partnering with Service to investigate and resolve.
  • Translate field and warranty data into actionable internal improvement projects.
  • Support customer audits, quality documentation requests, and complaint resolution with timely, data-driven responses.
  • Communicate quality performance, corrective actions, and improvement plans clearly to both internal stakeholders and external customers.

Cross-Functional Collaboration
  • Work daily with Manufacturing Engineering, Design Engineering, Production teams, Procurement, and Service to align on quality priorities and resolve issues collaboratively.
  • Participate in new product introduction (NPI) and design change processes to ensure manufacturability and quality requirements are addressed early.
  • Support internal and external audits and maintain relevant quality documentation and records.
  • Work the quality inspectors to report on quality metrics (defect rates, scrap, rework, warranty, supplier performance) and present findings to leadership.

Success in this role will be measured by:
  • Reduction in COPQ (Scrap, Rework, Warranty) Month over Month
  • Reduction in incoming inspection activities through Supplier capability improvements
  • Closure rate and effectiveness of CAPA/SCAR (no repeat issues)
  • Internal defect rates/ First Pass Yield improvements

Experience and Qualifications
  • 3-7 years of experience in a quality engineering, manufacturing engineering, or supplier quality role, preferably within a manufacturing environment (HVAC, appliance, heavy equipment, or similar regulated/mechanical product industry strongly preferred).
  • Demonstrated experience applying structured root cause and problem-solving methodologies (8D, A3, 5-Why, DMAIC, Six Sigma).
  • Working knowledge of statistical process control (SPC), measurement systems analysis (gauge R&R), and process capability studies (Cpk/Ppk).
  • Experience with supplier quality management, including supplier audits, SCARs, and PPAP or first article inspection processes.
  • Familiarity with FMEA development and control plan creation.
  • Experience working with ISO 9001 (or similar) quality management systems; experience with ASME, UL, or other boiler/water heater industry codes and standards is a plus.
  • Strong data analysis skills, including comfort working in Excel and/or quality/statistical software (Minitab or equivalent).
  • Excellent cross-functional communication skills, with the ability to work effectively with engineers, production personnel, suppliers, and customers.
  • Demonstrated ability to manage multiple priorities and drive corrective actions to closure independently.

Education and Training
  • Bachelor's degree in engineering (Quality, Mechanical, Industrial, Manufacturing, or related field) required; equivalent combination of education and relevant experience may be considered.
  • Six Sigma Green Belt or Black Belt certification preferred.
  • ASQ Certified Quality Engineer (CQE) or Certified Supplier Quality Professional (CSQP) preferred, or willingness to obtain.
  • Training or certification in core quality tools (FMEA, SPC, MSA, APQP/PPAP) preferred.

Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws.
For further information, please review the Know Your Rights notice from the Department of Labor.

Apply