1

Upstream Process Development Scientist Jobs in Seattle, WA

Sr. Process Integration Engineer

Seattle, WA ยท On-site +1

$113K - $160K/yr

Applied knowledge of material science and device physics as relates to semiconductor failure mechanisms and process development * Hands-on experience conducting failure analysis using SEM, TEM, FIB ...

Sr. Process Integration Engineer

Seattle, WA ยท On-site

$113K - $160K/yr

  • Medical

  • Retirement

  • PTO

Applied knowledge of material science and device physics as relates to semiconductor failure mechanisms and process development * Hands-on experience conducting failure analysis using SEM, TEM, FIB ...

Scientist I Biopreservation

Bothell, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

The Scientist I, Biopreservation is a core team member of the Research & Development Team. This ... Support development of end-to-end cell processing workflows involving cryopreserved starting ...

Principal Process Engineer

Redmond, WA ยท On-site

$134 - $154.10/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Develop strategies for the design and development of new and existing technologies across the ... Who You Are * BS in engineering, sciences, or related life science engineering 12+ years of ...

Scientist I, Analytical Sciences - Mass Spec

Seattle, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Omeros is seeking a Scientist, Analytical Sciences (Mass Spectrometry ) to provide strategic and ... method development, process development, manufacturing, formulation, Quality Assurance, and ...

Process Engineer 2

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Lead the development equipment maintenance & life cycle plans * Partner with Site MSAT ... Position Requirements: * BS in engineering, sciences, or related life science engineering 2-5 years ...

Process Engineer 2

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Lead the development equipment maintenance & life cycle plans * Partner with Site MSAT ... Position Requirements: * BS in engineering, sciences, or related life science engineering 2-5 years ...

Process Engineer 2

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Lead the development equipment maintenance & life cycle plans * Partner with Site MSAT ... Position Requirements: * BS in engineering, sciences, or related life science engineering 2-5 years ...

Sr. Applied Scientist, Prime AI/ML Science

Seattle, WA ยท On-site

$104K - $142K/yr

... processes for large scale data analyses, science development, science validation and model implementation. - Analyze and extract relevant information from large amounts of Amazon's historical ...

Process Engineer 2

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Lead the development equipment maintenance & life cycle plans * Partner with Site MSAT ... Position Requirements: * BS in engineering, sciences, or related life science engineering 2-5 years ...

Sr. Applied Scientist, Prime AI/ML Science

Seattle, WA ยท On-site

$104K - $142K/yr

... processes for large scale data analyses, science development, science validation and model implementation. - Analyze and extract relevant information from large amounts of Amazon's historical ...

Principal Process Engineer

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

What You'll Do: * Develop strategies for the design and development of new and existing ... Who You Are: * BS in engineering, sciences, or related life science engineering 12+ years of ...

Principal Process Engineer

Seattle, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

What You'll Do: * Develop strategies for the design and development of new and existing ... Who You Are: * BS in engineering, sciences, or related life science engineering 12+ years of ...

Principal Process Engineer

Redmond, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

What You'll Do: * Develop strategies for the design and development of new and existing ... Who You Are: * BS in engineering, sciences, or related life science engineering 12+ years of ...

Principal Process Engineer

Seattle, WA ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

What You'll Do: * Develop strategies for the design and development of new and existing ... Who You Are: * BS in engineering, sciences, or related life science engineering 12+ years of ...

Showing results 41-60

Upstream Process Development Scientist information

See Seattle, WA salary details

$23

$44

$70

How much do upstream process development scientist jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for upstream process development scientist in Seattle, WA is $44.00, according to ZipRecruiter salary data. Most workers in this role earn between $32.26 and $52.50 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an upstream process development scientist, and why are they important?

To thrive as an Upstream Process Development Scientist, you need a strong background in bioprocess engineering, cell culture, and molecular biology, typically supported by a degree in life sciences or biochemical engineering. Familiarity with bioreactor systems, analytical instrumentation, and data analysis software, as well as experience with cGMP and regulatory guidelines, is essential. Strong problem-solving abilities, teamwork, and effective communication help drive innovation and collaboration in the lab. These skills are crucial for optimizing cell culture processes, ensuring product quality, and meeting timelines in biopharmaceutical development.

What are some typical challenges faced by an upstream process development scientist, and how are they addressed in the workplace?

Upstream Process Development Scientists often encounter challenges such as optimizing cell culture conditions for maximum yield, scaling up processes from bench to pilot or production scale, and troubleshooting variability in biological systems. These challenges are typically addressed through rigorous experimental design, close collaboration with cross-functional teams like analytical development and quality assurance, and leveraging data-driven approaches to problem-solving. Regular team meetings and access to advanced instrumentation also provide support, ensuring that scientists can quickly adapt to evolving project needs and industry standards.

What does an upstream process development scientist do?

An Upstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes for the production of biological products such as proteins, vaccines, or antibodies. They primarily focus on cell culture, fermentation, and bioreactor operations to maximize yield and product quality. These scientists work closely with research and manufacturing teams to develop efficient and reproducible processes that can be transferred to large-scale production. Their work is essential in the biotechnology and pharmaceutical industries for the development of new therapeutics.

What is the difference between Upstream Process Development Scientist vs Downstream Process Development Scientist?

AspectUpstream Process Development ScientistDownstream Process Development Scientist
Focus AreaBioreactor cultivation, cell culture optimization, media developmentPurification, filtration, chromatography, product recovery
Skills & CertificationsCell biology, bioprocessing, GMP regulationsProtein chemistry, purification techniques, GMP compliance
Work EnvironmentLaboratories, bioreactors, pilot plantsLaboratories, purification facilities, pilot plants
Industry UsageBiopharmaceuticals, biotech companies, contract manufacturingBiopharmaceuticals, biotech companies, contract manufacturing

Both roles are essential in bioprocessing, with upstream scientists focusing on cell growth and media optimization, while downstream scientists handle product purification. They often collaborate closely within biopharmaceutical manufacturing to ensure efficient production and high-quality biologics.

What are popular job titles related to Upstream Process Development Scientist jobs in Seattle, WA?

For Upstream Process Development Scientist jobs in Seattle, WA, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development Scientist jobs in Seattle, WA look for?

The top searched job categories for Upstream Process Development Scientist jobs in Seattle, WA are:

Infographic showing various Upstream Process Development Scientist job openings in Seattle, WA as of August 2026, with employment types broken down into 67% Full Time, and 33% Contract. Highlights an 100% In-person job distribution, with an average salary of $91,520 per year, or $44 per hour.

Senior Research Associate - Analytical Development

BrainChild Bio

Seattle, WA

Full-time

Posted 29 days ago


Job description

BrainChild Bio Analytical Development team is seeking to hire a Senior Research Associate to add to our growing team. The Senior Research Associate will participate in routine analytical testing to enable process development and process characterization of early- to late-stage CAR-T manufacturing processes.
The ideal candidate will have experience in molecular biology techniques, particularly droplet digital PCR (ddPCR), and an interest in supporting assay development, qualification, and routine testing. They should be eager to learn new technologies and methodologies, be a problem solver, and work effectively across Analytical Development and Process Development teams to analyze samples and transfer methods. The candidate will also participate in ELN and SOP authoring.

Responsibilities:
· Work collaboratively with internal Process Development and Analytical Development teams.
· Assist with experimental execution in support of molecular assay development and qualification, including ddPCR/qPCR-based methods.
· Perform routine molecular analytics (e.g., ddPCR) and provide data in a timely manner to support process studies.
· Support development and execution of lentiviral vector characterization assays for process development and process characterization activities.
· Author ELNs, methods, reports and SOPs.

Qualifications:
· BA/BS in biochemistry, molecular biology, biology, microbiology or related discipline.
· 2–5 years of industry experience in a life sciences laboratory.
· Proficiency with life science data acquisition and analysis tools (Excel, Prism) and ELNs desired.
· Previous experience with molecular biology techniques (ddPCR/qPCR) and nucleic acid handling is highly desired.
· Experience supporting assay development, qualification and/or troubleshooting is a plus.
· A team player with a track record of successfully operating within cross-functional teams.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.