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Trial Master File Manager Jobs in Boston, MA (NOW HIRING)

Lumicell

Senior Clinical Trial Manager

Waltham, MA · On-site

Trial Master File and inspection readiness * Maintain oversight of study TMF completeness and ... Manage vendor deliverables and timelines, escalate risks, and track issue resolution. Required ...

Lumicell

Senior Clinical Trial Manager

Waltham, MA · On-site

Trial Master File and inspection readiness * Maintain oversight of study TMF completeness and ... Manage vendor deliverables and timelines, escalate risks, and track issue resolution. Required ...

Lumicell

Senior Clinical Trial Manager

Waltham, MA · On-site

Trial Master File and inspection readiness * Maintain oversight of study TMF completeness and ... Manage vendor deliverables and timelines, escalate risks, and track issue resolution. Required ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight,) * Coordinate and support regulatory submissions and ...

Alpha-9 Oncology

Clinical Trial Manager

Boston, MA · On-site

Responsible for maintaining internal study documents in the Trial Master File (TMF) and periodically reviewing the CRO TMF for completeness and accuracy. * Support forecasting and management of ...

Dyne Therapeutics

Senior Clinical Trial Associate

Waltham, MA · On-site

$36.25 - $49.25/hr

... manage competing priorities in a dynamic clinical development environment. This role is based in ... Collect, file, reconcile, and track essential documents for the trial master file (TMF); conduct ...

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Showing results 21-40

All JobsTrial Master File JobsTrial Master File Manager JobsTrial Master File Manager Jobs in Boston, MA

Trial Master File Manager information

See Boston, MA salary details

$48.3K

$82.1K

$123.8K

How much do trial master file manager jobs pay per year?

As of Aug 14, 2026, the average yearly pay for trial master file manager in Boston, MA is $82,104.00, according to ZipRecruiter salary data. Most workers in this role earn between $60,300.00 and $101,600.00 per year, depending on experience, location, and employer.

What are some common challenges faced by trial master file managers, and how can they be addressed?

Trial Master File Managers often encounter challenges such as ensuring TMF completeness, maintaining regulatory compliance, and coordinating document submissions across multiple stakeholders. Keeping documents up-to-date and audit-ready requires strong attention to detail and effective communication with clinical teams, vendors, and sponsors. Leveraging electronic TMF systems, implementing standardized processes, and promoting regular training can help address these challenges and ensure the integrity of the TMF throughout a study.

What is a trial master file manager?

A Trial Master File Manager is a professional responsible for overseeing the creation, maintenance, and quality control of the Trial Master File (TMF) in clinical research. The TMF is a collection of essential documents that allow the conduct of a clinical trial to be reconstructed and evaluated. The manager ensures that all documents are complete, accurate, and compliant with regulatory requirements throughout the trial's lifecycle. They work closely with clinical teams, auditors, and regulatory authorities to guarantee readiness for inspections and audits. Their role is crucial for maintaining transparency and credibility in clinical research processes.

What are the key skills and qualifications needed to thrive as a trial master file manager?

To thrive as a Trial Master File Manager, you typically need a strong background in clinical research, regulatory requirements, and document management, often supported by a degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, GCP guidelines, and relevant industry certifications like DIA's TMF Professional Certification is important. Attention to detail, organizational skills, and effective communication help ensure TMF integrity and coordination across cross-functional teams. These skills are crucial for maintaining regulatory compliance, audit readiness, and efficient clinical trial operations.

What are the most commonly searched types of Trial Master File jobs in Boston, MA?

The most popular types of Trial Master File jobs in Boston, MA are:

What are popular job titles related to Trial Master File Manager jobs in Boston, MA?

For Trial Master File Manager jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Trial Master File Manager jobs in Boston, MA look for?

The top searched job categories for Trial Master File Manager jobs in Boston, MA are:

What cities near Boston, MA are hiring for Trial Master File Manager jobs?

Cities near Boston, MA with the most Trial Master File Manager job openings:

Trial Master File Manager jobs near you
Infographic showing various Trial Master File Manager job openings in Boston, MA as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $82,114 per year, or $39.5 per hour.

TMF Documentation Coordinator

Integrated Resources INC

Cambridge, MA

Contractor

Re-posted 10 days ago

Job description

Company Description

A Few Words About Us - Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.

Job Description

Job Summary:

The primary purpose of this job is to file, QC, and remediate Medical Writing documentation required for Trial Master Files.

Uploads/files/performs quality control on documents to be submitted to the Trial Master File. Includes identification of missing documentation and follow-up with authors or other stakeholders to obtain missing items; performing quality reviews of files and any needed remediation (e.g., follow-up with sources, generating notes to file to explain any discrepancies); and completing file review documentation.

Responsible for ensuring timely filing of TMF documentation; addressing backlog of unfilled documentation; performing periodic review and remediation of TMF.


Qualifications

Qualifications:

Related Document Processing experience with Associate s degree

2+ yrs. with Bachelor's degree 

Quality control experience preferred.



Additional Information

Warm Regards,


Sneha Shrivastava


Clinical Recruiter


Integrated Resources, Inc


IT REHAB CLINICAL NURSING


Tel: (732) 549 2030 


Fax: (732) 549 5549


Inc. 5000 - 2007, 2008, 2009, 2010, 2011, 2012,2013 & 2014 (8th Year)


Certified MBE I GSA - Schedule 66 I GSA - Schedule 621I I GSA - Schedule 70



Integrated Resources logo

About Integrated Resources

Sourced by ZipRecruiter

Integrated Resources Inc (IRI), based in Edison, NJ, US, is an esteemed player in the staffing solutions industry with a credible presence on their official website irionline.com. Notably, IRI provides a range of professional staffing services including contract, contract-to-hire, and direct hire solutions to a wide spectrum of industries such as healthcare, life sciences, manufacturing, financial, insurance, and others. Since its inception, IRI has been committed to delivering top-talent and optimum solutions to meet its clients' diverse needs.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Edison, NJ, US

Year founded

1996

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