Translator In Usa Jobs in Boston, MA (NOW HIRING)

Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology

Translational Medicine in our Research & Development Division is responsible for planning and managing an important inflection point in the drug development process, working closely with scientific, regulatory, statistical, and modeling colleagues across the organization to translate the benchtop science of preclinical discovery into compounds ready for assessment in large clinical populations.

We are seeking a highly qualified physician‑scientist with a proven track record in both the pharmaceutical industry and independent academic research. The Senior Principal Scientist title is also equivalent to a Senior Medical Director position.

Translational Medicine Responsibilities

• Contribute to the identification of novel targets by partnering with discovery research teams to bring clinical insight into the earliest stages of target identification and validation, and execute clinical studies to evaluate relevance to human disease.
• Develop biomarker strategies through cross‑functional teams that provide line‑of‑sight from First‑in‑Human studies through clinical Proof‑of‑Concept, including Experimental Medicine studies to establish and/or validate novel clinical biomarker platforms.
• Develop and execute the early clinical development strategy for novel therapy/Immunology programs from Preclinical Candidate approval through clinical Proof‑of‑Concept (Phase 2a), and develop and execute clinical pharmacology strategies for late‑stage development programs from Proof‑of‑Concept (Phase 2a) through worldwide marketing application.

Primary Responsibilities

• Key member of an early development team, providing leadership in designing and executing early clinical development strategy.
• Develop and execute early clinical strategy for novel Immunology assets and therapeutics, including authoring initial clinical and biomarker plans for Lead Optimization programs, early clinical development plans for Preclinical Candidate molecules, Phase 1a/b trials and clinical pharmacology studies for programs in Phases I through IV of development.
• Develop and execute studies to validate clinical platforms utilizing established and novel biomarkers, including imaging, responses to interrogate biological activity in humans.
• Provide clinical expertise for identification and validation of novel targets, including the design of preclinical and/or clinical pharmacology experiments to validate targets and/or pathways.
• Safely and timely execute Phase I studies, collaborating closely with internal and external clinical study support staff and scientists.
• Provide clinical pharmacology support for programs through the worldwide marketing application filing, including supportive registration documents and presentations.
• Provide clear, timely communication and interpretation of study results to therapeutic area governance, functional area experts and development review committees.
• Contribute to assessment of internal and external opportunities identified by Business Development and Licensing.
• Interface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine‑EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late‑stage Clinical Research across sites in the USA, UK and Belgium.

Position Qualifications Education Minimum Requirement

• MD or MD/PhD.
• At least 5‑year experience in the pharmaceutical industry in clinical research, preferably in immunology clinical research, including translational research.
• Educational/career track including both independently conceived and executed research and clinical patient care experience.

Required Experience and Skills

• Proven track record in clinical research in the pharmaceutical industry.
• Proven track record in clinical care of patient populations or management of clinical problem‑solving, preferably in Dermatology.
• Demonstrated record of scientific scholarship and achievement; research expertise in any immunology field is preferred.
• Strong interpersonal, writing and presentation skills, and the ability to function in a team environment.
• Board Certification or Eligibility (MD and MD/PhD) preferred.

Required Skills

• Academic Research, Clinical Studies, Clinical Trial Development, Dermatology, Drug Development, Gastroenterology, Immunology, Intellectual Curiosity, Pharmaceutical Research, Rheumatology, Scientific Publications, Scientific Research, Translational Research.

EEO Statement

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

Accommodation

Our company is committed to inclusion and provides accommodations during the application or hiring process for candidates who need them. To request an accommodation, please contact the hiring team.

Hybrid Work Model

Effective September 5, 2023, employees in office‑based positions in the U.S. will be working a hybrid model consisting of three total days on‑site per week, Monday through Thursday, with Friday designated as a remote‑working day, unless business critical tasks require an on‑site presence. This model does not apply to field‑based, facility‑based, manufacturing‑based, or research‑based positions, or positions covered by collective‑bargaining agreements or designated as remote.

Salary

$286,900.00 – $451,600.00

Benefits

We offer a comprehensive package of benefits, including medical, dental, vision, healthcare and other insurance benefits, retirement benefits including 401(k), paid holidays, vacation, and compassionate and sick days.

Application Information

The application deadline for this position is listed in the posting. The posting remains open until 11:59:59 PM on the day before the listed job posting end date (05/7/2026).

Location

We welcome applicants from our Boston, MA, and other locations including West Point, PA; Upper Gwynned, PA; Rahway, NJ; and San Francisco, CA.

Travel Requirements

10%

Shift

Not Indicated

Valid Driving License

No

Hazardous Material(s)

n/a