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Translational Lead Jobs (NOW HIRING)

Serve as a preclinical biology lead or key scientific contributor for evaluation of business ... Translational Pharmacology and Disease Biology * Provide translational pharmacology expertise ...

$260K - $305K/yr

Lead and manage a team responsible for advancing multiple discovery and translational development programs from early concept through IND-enabling readiness. * Provide scientific and strategic ...

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How much do translational lead jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for translational lead in the United States is $22.20, according to ZipRecruiter salary data. Most workers in this role earn between $15.38 and $24.76 per hour, depending on experience, location, and employer.

What is a translational lead?

A Translational Lead is a professional in the biomedical or pharmaceutical field who oversees the process of translating scientific discoveries from the lab into clinical applications, such as new drugs or therapies. They bridge the gap between research and clinical development by coordinating multidisciplinary teams, designing translational strategies, and ensuring that promising research findings are effectively advanced into early-stage clinical trials. Their work is critical for accelerating the development of innovative treatments and ensuring that scientific breakthroughs reach patients more efficiently.

What are the typical cross-functional collaborations for a translational lead, and how do they influence project outcomes?

As a Translational Lead, you'll frequently collaborate with research scientists, clinical teams, regulatory affairs, and project management. These partnerships are essential for ensuring that scientific discoveries are effectively translated into viable clinical applications. Effective communication and coordination across these functions help streamline the development process, anticipate regulatory requirements, and address scientific challenges early. This collaborative approach not only accelerates project timelines but also increases the likelihood of successful outcomes for new therapies.

What are the key skills and qualifications needed to thrive as a translational lead, and why are they important?

To thrive as a Translational Lead, you need a strong background in biomedical sciences, drug development, and clinical research, often supported by a PhD or advanced degree. Familiarity with tools like clinical trial management systems (CTMS), data analytics platforms, and regulatory compliance software is common. Excellent project management, communication, and cross-functional collaboration skills are vital for bridging the gap between research and clinical application. These competencies ensure successful translation of scientific discoveries into viable therapies, driving innovation and patient impact.

What are popular job titles related to Translational Lead jobs?

For Translational Lead jobs, the most frequently searched job titles are:

Director, Translational Medicine Clinical Lead-Immunology

Cambridge, MA โ€ข On-site

Full-time

Retirement, PTO

Re-posted 9 days ago


Key responsibilities

  • Lead the clinical development and execution of early-phase immunology programs, including protocol design, monitoring, and data analysis.

  • Serve as the responsible physician and clinical lead for early development trials, ensuring milestones are met within timeline and budget.

  • Create and implement translational plans aligned with overall therapeutic area strategy, collaborating with cross-functional teams and external experts.


Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Clinical Development & Research - MD

Job Category:

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Director, Translational Medicine Clinical Lead, Translational Science & Medicine to be in Spring House, PA, La Jolla, CA or Cambridge, MA.

The Director, Translational Medicine (TM), will be a program and experimental medicine leader in the Immunology Translational Science and Medicine (TSM) function. In this position, the Director, TM, will decisively contribute to accelerating the Immunology pipeline from portfolio entry to Proof-of-Concept (PoC).

The Director, TM, will function as a clinical lead/study responsible physician on early development programs and trials. They will contribute to creating translational plans for programs that are aligned with overall TA strategy and with relevant disease area and/or pathway strategies. They will be empowered to lead a cross-functional clinical trial team to deliver on the trial's major execution milestones within governance-approved timeline and budget commitments. This responsibility extends end to end for clinical trials: from initial protocol design to continued monitoring and problem solving on trial execution to the analysis, interpretation, and communication of study results. This role will partner with Translational Sciences, and deep engagement with investigators and external experts is expected. In this leadership role, they will be supported by the senior leaders within the Translational Science and Medicine function, including the relevant disease area leaders (both in clinical development and biomarker science) and a clinical study responsible scientist. The span of studies in scope are phase 1 (including focused experimental medicine studies) through Proof of Concept.

Within TM, the Director will be part of a Translational Medicine Program Lead group which has primary responsibility within TSM for creating and implementing innovative translational plans for portfolio assets. TSM is a group within the Immunology Therapeutic Area, consisting of a Translational Medicine and Translational Science (TS). TM has combined expertise in the clinical study of immunologic disease, immunologic pathways, and in early clinical trial design and execution. TS has expertise in biomarker development, disease biology research, and in the application of immunology and data science technologies to support drug development. Organizationally, TSM serves as a pivotalbridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. This position will play a 'dual role', contributing both scientific and clinical development expertise to TSM projects.

Responsibilities are as follows:

  • Design and execute program translational strategies integrating both disease and pathway approaches.
  • Design and execute early clinical trials through PoC including experimental medicine studies.
  • Lead a cross-functional trial team to deliver on study milestones and commitments.
  • Collaborate with translational science on the development and implementation of clinical biomarker and patient segmentation strategies.
  • Support experimental medicine studies.
  • Support Business Development, including due diligence activities.
  • Represent TM on early development teams.
  • Represent TM for project teams when presenting to portfolio, project, and governance meetings.
  • Lead or participate in cross-functional working groups such as scientific and safety review boards.
  • Identify and collaborate with academic translational sites to optimize the translational strategy and plans for programs.
  • Prepare and/or direct the preparation and review of protocols, clinical study reports and translational medicine sections of Translational plans, IBs, INDs, abstracts, manuscripts, and technical reports.
  • Responsible for presentation of results and updates of projects at department, project, corporate and scientific meetings.

Qualifications:

  • MD or MD/PhD degree required.
  • Minimum of 3 years of industry and/or translational research experience required.
  • Demonstrated supervisory and/or leadership experience with clinical and/or research teams is required.
  • Training in Immunology and early clinical development trials is strongly preferred.
  • Experience with innovative immune cell-based or biologic therapies is preferred.
  • Experience in Oncology CAR-T and T cell engager therapies is not required but an area of interest.
  • Strong track record in publications is preferred.
  • Willingness and ability to travel, including trans-Atlantic travel (up to ~10%) is required.
  • Location is Spring House, PA, Cambridge, MA or La Jolla, CA.

Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

  • Vacation -120 hours per calendar year
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year
  • Holiday pay, including Floating Holidays -13 days per calendar year
  • Work, Personal and Family Time - up to 40 hours per calendar year
  • Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child
  • Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
  • Caregiver Leave - 80 hours in a 52-week rolling period10 days
  • Volunteer Leave - 32 hours per calendar year
  • Military Spouse Time-Off - 80 hours per calendar year

The anticipated base pay range for this position is: $199,000 - $398,000

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Required Skills:

Early Phase Clinical Trials, Experimental Research, Immunology Research, Translational Medicine

Preferred Skills:

Business Savvy, Clinical Research and Regulations, Clinical Trials, Collaboration, Consulting, Data Management and Informatics, Design Mindset, Drug Discovery Development, Industry Analysis, Innovation, Market Research, Regulatory Affairs Management, Research Ethics, Scientific Evaluation, Scientific Research, Stakeholder Management, Strategic Analysis

The anticipated base pay range for this position is :

$199,000.00 - $343,850.00

Additional Description for Pay Transparency: