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Temporary Downstream Process Development Jobs (NOW HIRING)

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lonza

Scientist II, Downstream

Houston, TX

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

MEDVACON

Aseptic Process Development - CDMO

IN · On-site

Our leading CDMO client is eager to hire an Aseptic Downstream Process Development SME for their Indianapolis site. This is a full-time role directly with the client - an outstanding opportunity to ...

Agilent

Process Engineer, Downstream

Frederick, CO · On-site

$124K - $194K/yr

Support Chemical Development in the development, characterization, and scaleup of innovative ... downstream unit operations and processes including: Column packing, preparative liquid ...

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How much do temporary downstream process development jobs pay per hour?

As of Jun 20, 2026, the average hourly pay for temporary downstream process development in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.
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Infographic showing various Temporary Downstream Process Development job openings in the United States as of June 2026, with employment types broken down into 6% As Needed, 6% Full Time, 77% Part Time, and 11% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $70,060 per year, or $33.7 per hour.
Associate Scientist - Process Development

Associate Scientist - Process Development

Lilly

Boston, MA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

This job post has expired today. Applications are no longer accepted.

Eli Lilly and Company rating

8.8

Company rating: 8.8 out of 10

Based on 62 frontline employees who took The Breakroom Quiz

10th of 71 rated pharmaceutical

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

We are seeking a highly motivated Principal Engineer to join the Downstream Process Development team. The successful candidate will lead development and optimization of downstream purification processes supporting viral vectorprograms from research through preclinical development.

The ideal candidate will possess deep technical expertise in downstream purification technologies including ultracentrifugation, chromatography, and tangential flow filtration (TFF), with demonstrated experience driving process development strategies, platform development initiatives, technology implementation, and multi-functional collaboration.

This role requires strong scientific leadership, hands-on technical capability, and the ability to independently lead complex purification development activities in a fast-paced environment.

Key Responsibilities

  • Lead development, optimization, and scale-up of downstream purification workflows for viral vectors.
  • Design and implement purification strategieusingngIodixanol andCsCldensity gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations.
  • Lead AKTA-based chromatography workflow development and process intensification initiatives.
  • Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs.
  • Independently design experiments, analyze data, interpret results, and present technical conclusions to multi-functional teams and leadership.
  • Drive troubleshooting, process characterization, and process robustness studies.
  • Collaborate closely with upstream, analytical, manufacturing, and external partners to support program deliverables and timelines.
  • Support technology transfer, process documentation, and development reports.
  • Lead development and optimization of TFF/UFDF workflows for concentration, buffer exchange, formulation, and process scalability.
  • Mentor junior scientists/engineers and provide technical guidance across purification activities.
  • Contribute to implementation of new purification technologies, automation tools, and continuous process improvements.
  • Ensure compliance with safety, documentation, and qualitystandards.

Basic Qualifications

  • Master's degree in biology, biochemistry, chemical engineering, biotechnology or related field
  • 8+ years of relevant downstream process development experience in industry
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Additional Skills/Preferences:

  • CsCland iodixanol ultracentrifugation
  • Affinity chromatography
  • Ion-exchange chromatography
  • TFF/UFDF operations including concentration, diafiltration, and formulation development
  • AKTA systems and Unicorn software
  • Strong understanding of process scale-up, platform development, and purification process characterization.
  • Experience analyzing purification performance and product quality attributes using relevant analytical methods.
  • Experience in AAV downstream process development and capsid enrichment workflows.
  • Experience with automated chromatography systems and process intensification strategies.
  • Experience supporting technology transfer and manufacturing readiness activities.
  • Familiarity with GMP development environments and regulatory expectations.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is

$71,250 - $187,000

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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About Eli Lilly

Sourced by ZipRecruiter

Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.

Industry

Pharmaceutical product wholesalers

Company size

10,000+ Employees

Headquarters location

Indianapolis, IN, US

Year founded

1876

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