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Technical Staff System Jobs (NOW HIRING)

... response systems. The space domain and the services provided by our Nation's satellites are ... Technical Staff: Group 93 is seeking a uniquely skilled individual to join our team as a member of ...

... response systems. The space domain and the services provided by our Nation's satellites are ... Technical Staff: Group 93 is seeking a uniquely skilled individual to join our team as a member of ...

... response systems. The space domain and the services provided by our Nation's satellites are ... Technical Staff: Group 93 is seeking a uniquely skilled individual to join our team as a member of ...

... technical marketing presentations and white papers for online publications and industry event promotional activities โ€ข Proactively engage in learning and researching new technologies and products ...

The Advanced Electro-Optical Systems Group (Group 99) specializes in the rapid design and ... Demonstrated ability to solve broad technical problems and complex engineering challenges Recent ...

The Advanced Electro-Optical Systems Group (Group 99) specializes in the rapid design and ... Demonstrated ability to solve broad technical problems and complex engineering challenges Recent ...

The Advanced Electro-Optical Systems Group (Group 99) specializes in the rapid design and ... Demonstrated ability to solve broad technical problems and complex engineering challenges Recent ...

Staff System Engineer

San Jose, CA ยท On-site

$160K - $185K/yr

The Staff System Engineer position provides an extraordinary opportunity support our Engineering ... Work with product managers and system engineers to draft technical marketing presentations and ...

Staff System Engineer

San Jose, CA ยท On-site

$160K - $185K/yr

The Staff System Engineer position provides an extraordinary opportunity support our Engineering ... Work with product managers and system engineers to draft technical marketing presentations and ...

As a Staff System Safety Engineer at Anduril, you will establish discipline philosophy across ... Provide expert technical direction on complex safety analyses including FHA, Fault Tree, SCFTA ...

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How much do technical staff system jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for technical staff system in the United States is $44.44, according to ZipRecruiter salary data. Most workers in this role earn between $41.35 and $47.60 per hour, depending on experience, location, and employer.

What cities are hiring for Technical Staff System jobs?

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Infographic showing various Technical Staff System job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 17% Part Time, 1% Temporary, and 5% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $92,439 per year, or $44.4 per hour.

Member of Technical Staff - System Engineering

South San Francisco, CA โ€ข On-site

$200K - $300K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 4 days ago


Job description

About Phylo
Phylo is an applied research lab building agentic intelligence to accelerate discovery for every biomedical scientist. We believe AI agents will fundamentally transform how biomedical research is done. Our fast-growing team brings together researchers and engineers across AI and biology, commercializing the Biomni platform.
Our growing team brings together world class researchers and engineers across AI and biology. Backed by a $13.5M seed round led by a16z, Menlo Ventures and Anthropic, and advised by Nobel Prize laureate and pioneering biologists, Phylo is building the next generation of AI systems for the life sciences.
About the Role
We're looking for an engineer to build and operate the core systems that power Phylo's agentic AI platform in production. You'll design and implement the distributed systems, compute environments, and service architecture that allow our AI agents to run reliably at scale - across cloud-native deployments and enterprise environments.
We are an AI-native engineering team: we use coding agents heavily, move fast, and hold a very high bar for engineering excellence.
What you'll do as a Member of Technical Staff - System Engineering at Phylo:
  • Design and build production systems that orchestrate agent execution and power AI-driven scientific workloads.
  • Build and operate scalable, reliable infrastructure across cloud, hybrid, and on-prem enterprise environments.
  • Develop systems for sandboxed execution, secure task isolation, and controlled compute environments. Design and implement security, access control, and compliance foundations suitable for enterprise deployments.
  • Design and operate the storage and data systems behind large-scale scientific workloads, including distributed file systems, object storage, and databases.
  • Partner closely with ML and science teams to translate computational workflows into robust, production-grade distributed systems.

What We're Looking For:
  • 3+ years of industry experience in backend, infrastructure, or distributed systems engineering.
  • Strong proficiency in at least one programming language (e.g., Python, Go, Rust, or similar).
  • Experience designing and operating distributed systems in production.
  • Deep hands-on experience with containerization and Kubernetes.
  • Experience with infrastructure-as-code tooling (e.g., Terraform, Pulumi, or equivalent).
  • Experience operating systems on at least one major cloud provider (AWS, GCP, or Azure).
  • Hands-on experience building or operating large-scale distributed file systems, storage platforms, or databases in production.
  • Comfort owning systems end-to-end in fast-moving, high-autonomy environments.

Nice to Haves:
  • Experience in building R&D infrastructure at Pharma/Biotech.
  • Experience supporting data-intensive scientific computing, bioinformatics, HPC, or ML workloads.
  • Experience with job orchestration, task scheduling, or workflow engines.
  • Experience with sandboxed or isolated execution frameworks (e.g., gVisor, Kata Containers, Firecracker).
  • Familiarity with distributed storage, observability systems, or high-performance compute environments.

Why Join Us?
  • Competitive salary and equity share in building the future of biomedical discovery
  • Full medical, dental, and vision coverage, including free therapy sessions and eyewear stipend
  • 401(k) to help you build long-term financial security (US only)
  • Unlimited PTO to recharge when you need it (US only)
  • Lunch and snacks when you're in the office
  • Regular team offsites and company events
  • A culture of excellence and speed - we move fast, think big, and support each other every step of the way
  • Your work will directly impact our mission to 100X biomedical discoveries through AI