Technical Infrastructure Program Manager Jobs in Massachusetts

Xometry is seeking a Staff Technical Program Manager to lead a high-stakes, multi-phase enterprise partnership. As a senior leader in our Technical Program Management organization, you will architect the operational framework for our most ambitious integration to date: embedding Xometry's proprietary AI directly into a major partner's ecosystem and software platforms.

This isn't a standard software rollout. You will be managing the "ideation-to-delivery" digital thread, coordinating the extraction of Xometry's core AI engines (DFM and IQE) and their native integration into our partner's PLM environment. You will bridge the gap between heavy-duty mechanical engineering workflows and agile AI/SaaS development, ensuring that "science fiction speed" becomes a reality for users globally.

This role requires a hybrid schedule (3 days a week) at our North Bethesda, MD or Waltham, MA office location.

• Program Architecture: Own the end-to-end management of this strategic Partnership Program. Design and institutionalize the operating rhythms (sprint cycles, risk management, executive readouts)

• Cross-Functional Execution: Drive alignment across Engineering, Data Science, Product, and our partner's internal technical teams. You will clarify scope, forecast resources, and unblock delivery for a program that operates directly on native 3D geometry rather than traditional mesh formats.

• Strategic Risk Management: Proactively identify and mitigate technical and jurisdictional risks, particularly regarding data governance (e.g., our partner's ring-fenced environments) and enterprise-grade deployment models

• Executive Communication: Act as the primary communications hub, producing crisp readouts for Xometry and partner leadership. You will facilitate high-stakes decision-making forums focused on technical trade-offs and roadmap prioritization.

• TPM Leadership: Serve as a senior thought partner to the Director of Technology Operations. You will help codify TPM best practices, mentor future hires, and establish the "gold standard" for how Xometry manages massive, multi-entity technical partnerships.

• Continuous Improvement: Champion "lessons learned" from this flagship integration to update Xometry's integration playbooks, helping us scale our AI-native platform to other global partners

• Experience: 10+ years of progressive experience in Technical Program Management, Engineering Management, or Product Management, with a focus on cross-functional software initiatives

• PLM/CAD Depth: A strong understanding of the design-to-manufacturing lifecycle. Experience with enterprise PLM, CAD, or industrial SaaS ecosystems (e.g., Dassault, Autodesk, or similar major platforms) is a significant advantage

• Complex Integration Expertise: Proven ability to manage deep-tier technical integrations (API-level and native) in high-growth or enterprise transformation environments

• Stakeholder Mastery: Exceptional influence skills, with a track record of aligning diverse groups-from Data Scientists and Geometric Engineers to C-suite executives

• Tooling & Data Fluency: Mastery of program management tooling (Jira, advanced visualization, etc.) and a data-driven approach to tracking milestones and SLIs/SLOs

• Education: Bachelor's degree in Computer Science, Mechanical Engineering, or a related technical field; an advanced degree is a plus

• Background in Manufacturing: Deep familiarity with DFM (Design for Manufacturability), 3D modeling, or B2B industrial marketplaces

• First-of-Kind Experience: Experience being a "first-in" or "founding" TPM for a high-priority strategic initiative

• Operational Agility: The ability to balance a rigorous, enterprise-grade deployment with the high-velocity, AI-native culture of Xometry

The estimated base salary range for new hires into this role is $156,000 - $185,000 annually + bonus, depending on factors such as job-related skills, relevant experience, and location. The total compensation package includes base, bonus/commission, and equity. We also offer a competitive benefits package, including 401(k) match, medical, dental and vision insurance; life and disability insurance; generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave; EAP, other wellbeing resources; and much more.

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