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Systems Engineer Jobs in Greenville, SC (NOW HIRING)

Interim HealthCare

Senior Systems Engineer

Greenville, SC · On-site

$115K - $125K/yr

Senior Systems Engineer in Greenville, SC Are you a seasoned Microsoft systems expert ready to lead enterprise-level infrastructure, security, and modernization initiatives in a dynamic, healthcare ...

Courser

Systems Engineer I

Greenville, SC · On-site

Systems Engineer An MSP Systems Engineer (Managed Service Provider Systems Engineer) is a professional responsible for managing and supporting the IT infrastructure of client organizations within a ...

Quest Global

Packaged Systems Engineer

Greenville, SC

$90K - $105K/yr

We are seeking a highly skilled and experienced Packaged Systems Engineer with strong expertise in DCS (Distributed Control Systems) and Balance of Plant (BOP) cabinet engineering for Power plant ...

Courser

Security Systems Engineer

Greenville, SC · On-site

Security Systems Engineer We are seeking a proactive Security Systems Engineer to serve as a technical lead for Courser's core Microsoft 365 environment and security operations. This hybrid role is ...

Transitions Group

Security Systems Engineer

Greenville, SC · On-site

$95 - $150/hr

Security Systems Engineer We are seeking a proactive Security Systems Engineer to serve as a technical lead for Courser's core Microsoft 365 environment and security operations. This hybrid role is ...

New

Sttark

Be Seen First

Mechanical Engineer/ Systems Engineer

Greenville, SC · On-site

$80K - $95K/yr

Title Mechanical Engineer/ Systems Engineer The Role We build our own manufacturing machines. Not just specify them, not just improve them: we design, fabricate, wire, program, and commission custom ...

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All JobsSystems Engineer JobsSystems Engineer Jobs in Greenville, SC

Systems Engineer information

See Greenville, SC salary details

$50.3K

$119.6K

$157K

How much do systems engineer jobs pay per year?

As of Aug 30, 2026, the average yearly pay for systems engineer in Greenville, SC is $119,619.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,100.00 and $147,600.00 per year, depending on experience, location, and employer.

What is a systems engineer?

Systems engineers are professionals who design, integrate, and manage complex systems throughout their life cycles. They work across various industries, ensuring that all aspects of a project or system—hardware, software, processes, and people—work together efficiently and effectively. Systems engineers coordinate between different engineering teams, address technical and organizational challenges, and ensure requirements are met. Their role often involves both big-picture thinking and attention to detail to deliver reliable and scalable solutions.

What does a systems engineer do?

The role of a systems engineer varies based on the company they work for, but in every industry systems engineers use computerized systems to keep track of all the moving parts within their organizations. The term systems engineer usually refers to a computer systems engineer, which combines several disciplines to create, purchase, and install a computer system that suits the needs of each particular client. They will also work in a hands-on manner during the installation, acquisition, testing, and implementation phases of the project. Duties typically include making recommendations for scalability, troubleshooting any problems that arise during the use of the system, reviewing a company’s security requirements, and recommending security measures to allow the company to avoid compromising any sensitive data.

What are the key skills and qualifications needed to thrive as a systems engineer, and why are they important?

To thrive as a Systems Engineer, you need a strong background in systems architecture, troubleshooting, and integration, typically supported by a degree in computer science or engineering. Familiarity with operating systems (like Linux and Windows), virtualization platforms, scripting languages, and certifications such as CompTIA, Cisco (CCNA), or Microsoft (MCSA) are commonly required. Strong problem-solving abilities, effective communication, and teamwork make candidates stand out in this role. These skills and qualifications ensure the design, implementation, and maintenance of reliable, scalable systems critical for organizational operations.

How does a systems engineer typically collaborate with cross-functional teams during a project lifecycle?

Systems Engineers often serve as a bridge between various technical and non-technical teams, including software developers, network specialists, project managers, and end users. Throughout a project, they participate in requirements gathering, design reviews, and integration testing, ensuring that each component fits seamlessly within the overall system. Effective communication and documentation are crucial, as Systems Engineers must translate complex technical concepts into actionable tasks for diverse stakeholders. This collaborative approach not only streamlines problem-solving but also helps deliver robust, scalable solutions.

What is the difference between Systems Engineer vs Network Engineer?

AspectSystems EngineerNetwork Engineer
CertificationsCompTIA Network+, Cisco CCNA, Microsoft certificationsCompTIA Network+, Cisco CCNA, Juniper JNCIA
Work EnvironmentDesigning, implementing, and managing IT systems and infrastructureDesigning, configuring, and maintaining network hardware and connectivity
Industry UsageIT, technology, enterprise solutionsTelecommunications, IT, networking service providers
Common TasksSystem integration, troubleshooting, server managementNetwork setup, routing, switching, security

While both roles involve technical expertise in IT infrastructure, Systems Engineers focus on overall system architecture and integration, whereas Network Engineers specialize in network hardware, connectivity, and security. Understanding these differences helps employers and professionals align skills with job requirements.

Is a systems engineer a high paying job?

Systems engineers typically earn above-average salaries compared to many other technical roles, with compensation varying based on experience, certifications, and location. They often work in industries such as technology, aerospace, and defense, where specialized skills and knowledge of tools like network systems and software are valued. Advanced certifications and experience can lead to higher pay levels in this field.

Is a systems engineer a stressful job?

Systems engineers often face stressful situations due to tight deadlines, complex problem-solving, and the need for high reliability in systems. The role can involve long hours and on-call responsibilities, especially during system outages or critical updates, but it also offers opportunities for problem-solving and technical growth.
More about Systems Engineer jobs

What are the most commonly searched types of Systems Engineer jobs in Greenville, SC?

The most popular types of Systems Engineer jobs in Greenville, SC are:

What job categories do people searching Systems Engineer jobs in Greenville, SC look for?

The top searched job categories for Systems Engineer jobs in Greenville, SC are:

What cities near Greenville, SC are hiring for Systems Engineer jobs?

Cities near Greenville, SC with the most Systems Engineer job openings:

Systems Engineer jobs near you
Infographic showing various Systems Engineer job openings in Greenville, SC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $119,619 per year, or $57.5 per hour.

Senior Systems Engineer

Interim HealthCare - Central Recruiting

Greenville, SC

$115K - $125K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 13 days ago

Job description

Senior Systems Engineer

in Greenville, SC

Are you a seasoned Microsoft systems expert ready to lead enterprise-level infrastructure, security, and modernization initiatives in a dynamic, healthcare-driven environment? Interim HealthCare is seeking a Sr. Systems Engineer with deep technical expertise, a strategic mindset, and a passion for designing secure, scalable, and resilient solutions.

In this pivotal role, you’ll serve as a senior technical authority across Microsoft systems, cloud technologies, cybersecurity, and VOIP—leading architecture decisions, driving infrastructure improvements, and strengthening our overall technology posture. You’ll operate as a Tier 3 escalation point, partner with cross-functional teams and franchise stakeholders, and play a key role in shaping the future of our IT environment.

If you thrive in complex environments, enjoy solving high-impact technical challenges, and want to influence how technology supports healthcare delivery at scale, this is the opportunity for you.

Why You’ll Enjoy Being Part of Our Team:

  • Competitive Pay: $115,000 - $125,000 per year, based on experience
  • Meaningful impact: Use your technical expertise to design and support systems that directly enable patient care and operational excellence. 
  • Supportive Culture: Join a collaborative, family-oriented environment that values innovation, accountability, and continuous improvement.
  • Comprehensive Benefits: Enjoy PTO, holiday pay, medical, dental, and vision coverage, along with 401(k) benefits.

Big-Picture Overview: What You'll Do as a Senior Systems Engineer:

  • Administer and optimize On-Premises Active Directory and Azure AD Connect, ensuring secure hybrid identity, SSO, and efficient replication.
  • Oversee Microsoft 365 services (Exchange, SharePoint, OneDrive, Teams), ensuring reliable collaboration and system performance.
  • Design, implement, and support VMware virtual infrastructures and VOIP systems, focusing on scalability, resilience, and successful migrations.
  • Act as a Tier 3 escalation point for complex technical issues, driving root cause analysis, long-term solutions, and operational improvements.
  • Lead cybersecurity initiatives, including vulnerability mitigation, incident response, and system hardening.
  • Develop and maintain backup, recovery, and disaster recovery strategies to ensure business continuity.
  • Collaborate with internal teams and franchise locations to provide expert guidance, document technical procedures, and support IT project delivery.

Must-Haves for Success in This Role:

  • This will be a full-time, onsite position in Greenville, SC. 
  • Bachelor’s degree or equivalent experience in a related field.
  • 5+ years of progressive experience as a Senior Systems Engineer.
  • 10–15 years as a Microsoft Systems Engineer or in a similar technical role.
  • 10+ years managing VMware virtual infrastructures and VOIP environments, including migration leadership.
  • Strong expertise in cybersecurity principles, risk mitigation, and enterprise system hardening.
  • Exceptional problem-solving, analytical, and conceptual skills with the ability to influence technical decisions.
  • Ability to work independently while effectively collaborating with leadership, stakeholders, and cross-functional teams.

Why Work for Interim HealthCare? 

Founded in 1966, Interim HealthCare is the nation’s first home health company and a trusted leader in compassionate, patient-centered care. With 300+ locations nationwide, we foster a family-oriented culture that values every team member. As a Senior Systems Engineer, you’ll play a critical role in supporting and advancing the technology that enables exceptional care delivery—ensuring systems are secure, reliable, and built for the future.

Interim HealthCare is an equal-opportunity employer committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

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