Responsibilities may include conducting independent and collaborative research in structural proteomics, chemical biology, and mitochondrial biology; developing and implementing mass spectrometry ...
Responsibilities may include conducting independent and collaborative research in structural proteomics, chemical biology, and mitochondrial biology; developing and implementing mass spectrometry ...
The overarching goal of this project is to leverage human pluripotent stem cell technology and advanced structural biology methods to define mechanisms and rules of sarcomere assembly and function.
The overarching goal of this project is to leverage human pluripotent stem cell technology and advanced structural biology methods to define mechanisms and rules of sarcomere assembly and function.
This role offers the opportunity to work at the intersection of protein biochemistry and cutting-edge structural biology, contributing to our mission of accelerating drug discovery through advanced ...
This role offers the opportunity to work at the intersection of protein biochemistry and cutting-edge structural biology, contributing to our mission of accelerating drug discovery through advanced ...
Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit-to-lead and lead optimization. * Technical Leadership:
Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit-to-lead and lead optimization. * Technical Leadership:
The Fischer lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles that govern signaling through ...
The Fischer lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles that govern signaling through ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Work cross-functionally with partners in Medicinal Chemistry, Structural Biology, Discovery Biology, Translational Research, and Cancer Immunology to prioritize oncology targets, implement hit ...
Work cross-functionally with partners in Medicinal Chemistry, Structural Biology, Discovery Biology, Translational Research, and Cancer Immunology to prioritize oncology targets, implement hit ...
The Blanchard laboratory in the Department of Structural Biology at St. Jude Children's Research Hospital is seeking a highly motivated Postdoctal student with experience in molecular biology ...
The Blanchard laboratory in the Department of Structural Biology at St. Jude Children's Research Hospital is seeking a highly motivated Postdoctal student with experience in molecular biology ...
The successful candidate will join a well-equipped structural biology program focused on single particle cryoEM, X ray crystallography, protein biochemistry, membrane reconstitution, and quantitative ...
The successful candidate will join a well-equipped structural biology program focused on single particle cryoEM, X ray crystallography, protein biochemistry, membrane reconstitution, and quantitative ...
Postdoctoral Fellow-MSH-30001-321
Manhattan, NY · On-site
$72K - $80K/yr
Employ structural biology techniques to study and understand the structure, function, and dynamics of disease-related proteins and protein-ligand complexes. * Contribute to structure-assisted drug ...
Postdoctoral Fellow-MSH-30001-321
Manhattan, NY · On-site
$72K - $80K/yr
Employ structural biology techniques to study and understand the structure, function, and dynamics of disease-related proteins and protein-ligand complexes. * Contribute to structure-assisted drug ...
Expert in analyzing structural biology and multi-omics (e.g., genomics, proteomics) data, provide deep biological context to AI-driven findings, generate mechanistic hypotheses for novel drug targets ...
Expert in analyzing structural biology and multi-omics (e.g., genomics, proteomics) data, provide deep biological context to AI-driven findings, generate mechanistic hypotheses for novel drug targets ...
Be Seen First
Principal Scientist - X-ray Crystallography
Kalamazoo, MI · On-site
$120K - $140K/yr
This is a unique opportunity for an accomplished structural biologist to shape a new laboratory from the ground up, define its operational standards, and build external partnerships that will support ...
Quick apply
Be Seen First
Principal Scientist - X-ray Crystallography
Kalamazoo, MI · On-site
$120K - $140K/yr
This is a unique opportunity for an accomplished structural biologist to shape a new laboratory from the ground up, define its operational standards, and build external partnerships that will support ...
Research Associate II/ Senior Research Associate
Andover, MA · On-site
$85K - $111K/yr
MSc in Biochemistry, Structural Biology, Biophysics, Molecular Biology, Chemistry, or a related field and 0-2+ years of experience, or a BSc in Biochemistry, Structural Biology, Biophysics, Molecular ...
Research Associate II/ Senior Research Associate
Andover, MA · On-site
$85K - $111K/yr
MSc in Biochemistry, Structural Biology, Biophysics, Molecular Biology, Chemistry, or a related field and 0-2+ years of experience, or a BSc in Biochemistry, Structural Biology, Biophysics, Molecular ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at Mayo Clinic. The ...
Postdoctoral Fellow - Genomic Medicine
$64K - $76K/yr
We seek a driven and technically adept Postdoctoral Fellow with prior experience in cryo-electron microscopy and/or other structural biology techniques. The successful candidate will independently ...
Postdoctoral Fellow - Genomic Medicine
$64K - $76K/yr
We seek a driven and technically adept Postdoctoral Fellow with prior experience in cryo-electron microscopy and/or other structural biology techniques. The successful candidate will independently ...
Responsibilities Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at ...
Responsibilities Research Fellow - Structural and Cellular Biology A postdoctoral position is available in the laboratory of Dr. Georges Mer in the Department of Biochemistry and Molecular Biology at ...
Postdoctoral Fellow - Genomic Medicine
Houston, TX · On-site
$64K - $76K/yr
We seek a driven and technically adept Postdoctoral Fellow with prior experience in cryo-electron microscopy and/or other structural biology techniques. The successful candidate will independently ...
Postdoctoral Fellow - Genomic Medicine
Houston, TX · On-site
$64K - $76K/yr
We seek a driven and technically adept Postdoctoral Fellow with prior experience in cryo-electron microscopy and/or other structural biology techniques. The successful candidate will independently ...
Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit-to-lead and lead optimization. * Technical Leadership:
Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit-to-lead and lead optimization. * Technical Leadership:
Scripps Staff Scientist Join a dynamic structural biology group at the Wertheim UF Scripps Institute, where we push the boundaries of molecular visualization and membrane biology. Our lab integrates ...
Scripps Staff Scientist Join a dynamic structural biology group at the Wertheim UF Scripps Institute, where we push the boundaries of molecular visualization and membrane biology. Our lab integrates ...
Structural Biology information
See salary details
$15.38 - $16.87
1% of jobs
$16.87 - $18.36
7% of jobs
$18.36 - $19.84
13% of jobs
$20.24 is the 25th percentile. Wages below this are outliers.
$19.84 - $21.33
14% of jobs
$21.33 - $22.81
14% of jobs
The median wage is $22.92 / hr.
$22.81 - $24.30
15% of jobs
$25.42 is the 75th percentile. Wages above this are outliers.
$24.30 - $25.79
15% of jobs
$25.79 - $27.27
16% of jobs
$27.27 - $28.76
5% of jobs
$28.76 - $30.24
0% of jobs
$30.24 - $31.73
0% of jobs
$15
$23
$31
How much do structural biology jobs pay per hour?
As of Jun 14, 2026, the average hourly pay for structural biology in the United States is $23.42, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $25.72 per hour, depending on experience, location, and employer.
What are the key skills and qualifications needed to thrive in the Structural Biology position, and why are they important?
To thrive in Structural Biology, you need a strong background in molecular biology, biochemistry, and physics, generally supported by an advanced degree (MS or PhD) in a related field. Proficiency with specialized software for molecular modeling (such as PyMOL or Chimera), as well as hands-on experience with technologies like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy, is essential. Attention to detail, analytical thinking, and collaborative communication are crucial soft skills in this role. These skills and qualifications are key for accurately determining biomolecular structures and contributing valuable insights to biomedical research and drug discovery.
What are the typical daily responsibilities of someone working in Structural Biology?
Professionals in Structural Biology commonly spend their days designing and conducting experiments to analyze the three-dimensional structures of biological macromolecules using techniques like X-ray crystallography, cryo-EM, or NMR spectroscopy. They often collaborate with interdisciplinary teams—including biochemists, computational modelers, and pharmaceutical researchers—to interpret data and inform research directions. In addition to laboratory work, significant time is dedicated to data analysis, preparing research presentations, and staying up to date with scientific literature. This dynamic environment requires flexibility, technical expertise, and an eagerness to solve complex scientific problems.
What is a Structural Biology job?
A Structural Biology job involves studying the molecular structure and function of biological macromolecules, such as proteins and nucleic acids, to understand their roles in cellular processes. Professionals in this field use techniques like X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy to determine molecular structures. These roles are common in academic research, pharmaceutical development, and biotechnology companies, contributing to drug discovery and disease research.
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Full-time
Posted 13 days ago
University Of Pennsylvania rating
8.1
Based on 80 frontline employees who took The Breakroom Quiz
130th of 537 rated colleges and universities
Job description
Description
The Department of Physiology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of mass spectrometry-based proteomics, including experience with LC-MS/MS instrumentation, experimental design, and proteomics data analysis. Candidates should possess strong expertise in protein biochemistry, molecular biology, and quantitative proteomics approaches. A strong record of original peer-reviewed publications, scientific leadership, communication, and interpersonal skills is required. Applicants must have a Ph.D. or M.D./Ph.D. degree.
Responsibilities may include conducting independent and collaborative research in structural proteomics, chemical biology, and mitochondrial biology; developing and implementing mass spectrometry-based workflows including chemical crosslinking mass spectrometry (XL-MS), quantitative proteomics, and protein interaction mapping; operating and maintaining advanced LC-MS/MS instrumentation; analyzing complex proteomics datasets; mentoring students and trainees; contributing to manuscript preparation, grant writing, and collaborative research projects.
The successful applicant will have an opportunity to establish and lead new structural proteomics and crosslinking mass spectrometry capabilities within a newly established research program; develop independent research projects at the interface of proteomics, structural biology, neuroscience, and reproductive biology; collaborate with investigators across Penn's structural biology, proteomics, mitochondrial biology, and neuroscience communities; receive mentorship in laboratory leadership, grant writing, project development, and career advancement; and contribute to high-impact interdisciplinary research programs.
Candidates should have demonstrated experience designing and executing independent research projects and working effectively within collaborative multidisciplinary teams. Experience with Orbitrap-based mass spectrometry platforms, quantitative proteomics workflows, and advanced proteomics software tools is required.
Preferred qualifications include expertise in chemical crosslinking mass spectrometry (XL-MS), structural proteomics, protein interaction mapping, chemical biology, development of novel analytical methodologies, and computational analysis of proteomics datasets. Experience with mitochondrial biology, neuroscience, reproductive biology, cryo-EM, or integrative structural biology is desirable but not required.
Qualifications
Ph.D. or M.D./Ph.D.
The Department of Physiology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of mass spectrometry-based proteomics, including experience with LC-MS/MS instrumentation, experimental design, and proteomics data analysis. Candidates should possess strong expertise in protein biochemistry, molecular biology, and quantitative proteomics approaches. A strong record of original peer-reviewed publications, scientific leadership, communication, and interpersonal skills is required. Applicants must have a Ph.D. or M.D./Ph.D. degree.
Responsibilities may include conducting independent and collaborative research in structural proteomics, chemical biology, and mitochondrial biology; developing and implementing mass spectrometry-based workflows including chemical crosslinking mass spectrometry (XL-MS), quantitative proteomics, and protein interaction mapping; operating and maintaining advanced LC-MS/MS instrumentation; analyzing complex proteomics datasets; mentoring students and trainees; contributing to manuscript preparation, grant writing, and collaborative research projects.
The successful applicant will have an opportunity to establish and lead new structural proteomics and crosslinking mass spectrometry capabilities within a newly established research program; develop independent research projects at the interface of proteomics, structural biology, neuroscience, and reproductive biology; collaborate with investigators across Penn's structural biology, proteomics, mitochondrial biology, and neuroscience communities; receive mentorship in laboratory leadership, grant writing, project development, and career advancement; and contribute to high-impact interdisciplinary research programs.
Candidates should have demonstrated experience designing and executing independent research projects and working effectively within collaborative multidisciplinary teams. Experience with Orbitrap-based mass spectrometry platforms, quantitative proteomics workflows, and advanced proteomics software tools is required.
Preferred qualifications include expertise in chemical crosslinking mass spectrometry (XL-MS), structural proteomics, protein interaction mapping, chemical biology, development of novel analytical methodologies, and computational analysis of proteomics datasets. Experience with mitochondrial biology, neuroscience, reproductive biology, cryo-EM, or integrative structural biology is desirable but not required.
Qualifications
Ph.D. or M.D./Ph.D.
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About University of Pennsylvania
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The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Employers By State in 2021.
Industry
Colleges, universities, and professional schools
Company size
10,000+ Employees
Headquarters location
Philadelphia, PA, US
Year founded
1740