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Structural Biology Jobs (NOW HIRING)

Output, Inc

Head of Biology

New York, NY · On-site

You have a PhD in computational biology, biophysics, structural biology, molecular biology, or a related biological field with 3+ years of post-doctoral or industry research experience * You have ...

Namely

Head of Biology

Manhattan, NY · On-site

$100 - $125/hr

You have a PhD in computational biology, biophysics, structural biology, molecular biology, or a related biological field with 3+ years of post-doctoral or industry research experience * You have ...

Output Biosciences

Head of Biology

New York, NY · On-site

You have a PhD in computational biology, biophysics, structural biology, molecular biology, or a related biological field with 3+ years of post-doctoral or industry research experience * You have ...

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How much do structural biology jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for structural biology in the United States is $23.42, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $25.72 per hour, depending on experience, location, and employer.

What is structural biology?

A Structural Biology job involves studying the molecular structure and function of biological macromolecules, such as proteins and nucleic acids, to understand their roles in cellular processes. Professionals in this field use techniques like X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy to determine molecular structures. These roles are common in academic research, pharmaceutical development, and biotechnology companies, contributing to drug discovery and disease research.

What does someone working in structural biology do?

Professionals in Structural Biology commonly spend their days designing and conducting experiments to analyze the three-dimensional structures of biological macromolecules using techniques like X-ray crystallography, cryo-EM, or NMR spectroscopy. They often collaborate with interdisciplinary teams—including biochemists, computational modelers, and pharmaceutical researchers—to interpret data and inform research directions. In addition to laboratory work, significant time is dedicated to data analysis, preparing research presentations, and staying up to date with scientific literature. This dynamic environment requires flexibility, technical expertise, and an eagerness to solve complex scientific problems.

What are the key skills and qualifications needed to thrive in structural biology?

To thrive in Structural Biology, you need a strong background in molecular biology, biochemistry, and physics, generally supported by an advanced degree (MS or PhD) in a related field. Proficiency with specialized software for molecular modeling (such as PyMOL or Chimera), as well as hands-on experience with technologies like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy, is essential. Attention to detail, analytical thinking, and collaborative communication are crucial soft skills in this role. These skills and qualifications are key for accurately determining biomolecular structures and contributing valuable insights to biomedical research and drug discovery.

Is structural biology in demand?

Structural biology is a growing field with demand in pharmaceuticals, biotechnology, and academic research for understanding molecular mechanisms. Professionals in this area often work with techniques like X-ray crystallography, cryo-electron microscopy, and molecular modeling, and strong skills in these methods can enhance job prospects. The field offers opportunities in research institutions, biotech companies, and drug development firms.
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Structural Biology jobs near you
Infographic showing various Structural Biology job openings in the United States as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $48,717 per year, or $23.4 per hour.

Research Assistant - Structural Bioinformatics

Astera Institute

Emeryville, CA • On-site

$60 - $80/hr

Other

Posted 7 days ago

Job description

About Astera:

Astera is a private foundation on a mission to steer science and technology toward an abundant future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to dramatically accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive scientific progress.

Unlike traditional non‑profit research organizations, projects supported by Astera operate like high‑velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. You can read more about our mission, vision, and programming here.

About the Role:

The diffUSE Project at Astera Institute/Radial is building open infrastructure for dynamic structural biology, making protein conformational and ensemble data findable, validated, and reusable at scale. The Research Assistant will support this mission by maintaining data pipelines, curating structural datasets, and running validation checks across X‑ray, cryo-EM, and ensemble‑derived data, working closely with Scientists and software engineers on day‑to‑day technical execution. This is a full‑time, in‑person role suited to someone early in their research career who wants hands‑on exposure to structural biology data infrastructure in a fast‑moving, multidisciplinary environment. The ideal candidate is detail‑oriented, comfortable with ambiguity, and motivated by the goal of making scientific data more open and reusable.

Key Responsibilities
  • Maintain and run bioinformatic pipelines for structural data processing, curation, and quality control.
  • Support development and benchmarking of validation metrics against experimental datasets.
  • Assist with data deposition, formatting, and documentation to meet community data standards.
  • Help prepare datasets, figures, and summaries for publications, reports, and presentations.
  • Coordinate with Scientists and engineers on routine data management tasks and troubleshooting.
Required Skills and Qualifications
  • BS or MS in bioinformatics, structural biology, computational biology, or a related field.
  • Working proficiency in Python and familiarity with structural file formats (PDB, mmCIF, mtz).
  • Strong organizational skills and close attention to detail in data handling.
  • Comfortable working across computational and experimental teams in a research setting.
  • Preferred: exposure to crystallography or cryo‑EM data processing; familiarity with PDB, EMDB, or related databases.
Compensation

Commensurate with experience.

  • Benefits summary
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