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Staff Machine Learning Engineer Jobs in Boston, MA

Senior Machine Learning Engineer

Boston, MA · Remote

$125K - $165K/yr

Position Summary The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data ...

Senior Machine Learning Engineer

Boston, MA · On-site +1

$133K - $175K/yr

Position Summary The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data ...

Senior Machine Learning Engineer

Boston, MA · On-site +1

$133K - $175K/yr

Position Summary The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data ...

Machine Learning Engineer

Woburn, MA · On-site

$115K - $140K/yr

The Role As a Machine Learning Engineer, you will help develop and integrate cutting-edge AI/ML models into production systems that solve critical national security problems. Working as part of a ...

Machine Learning Engineer

Boston, MA · On-site

$115K - $140K/yr

The Role As a Machine Learning Engineer, you will help develop and integrate cutting-edge AI/ML models into production systems that solve critical national security problems. Working as part of a ...

We are seeking a mid-level Machine Learning Engineer to help develop and scale RAG systems across the company. This is a hands-on, full-lifecycle ML role with a strong emphasis on retrieval models ...

Machine Learning Engineer

Woburn, MA · On-site

$115K - $140K/yr

The Role As a Machine Learning Engineer, you will help develop and integrate cutting-edge AI/ML models into production systems that solve critical national security problems. Working as part of a ...

Machine Learning Engineer

Woburn, MA · On-site

$115K - $140K/yr

The Role As a Machine Learning Engineer, you will help develop and integrate cutting-edge AI/ML models into production systems that solve critical national security problems. Working as part of a ...

Showing results 41-60

Staff Machine Learning Engineer information

See Boston, MA salary details

$25K

$107.9K

$209.1K

How much do staff machine learning engineer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for staff machine learning engineer in Boston, MA is $107,906.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,000.00 and $135,800.00 per year, depending on experience, location, and employer.

What is a staff machine learning engineer?

A Staff Machine Learning Engineer is a senior-level technical role responsible for designing, deploying, and optimizing machine learning models at scale. They provide technical leadership, mentor other engineers, and drive best practices in ML system architecture. This role often involves collaborating with cross-functional teams, improving model performance, and ensuring the reliability of machine learning solutions in production. Staff ML Engineers typically have deep expertise in algorithms, data infrastructure, and engineering processes. Their work focuses on solving complex problems and influencing the broader ML strategy within an organization.

What are the typical collaboration and leadership responsibilities for a staff machine learning engineer?

As a Staff Machine Learning Engineer, you often serve as a technical leader, partnering with cross-functional teams including data scientists, product managers, and software engineers to develop and deploy machine learning solutions. You will mentor junior engineers, conduct code reviews, and help establish best practices for model development and deployment. In addition to hands-on technical work, you may be responsible for evaluating new tools, contributing to the broader ML strategy, and facilitating knowledge sharing sessions. This collaborative and leadership-focused approach helps ensure consistency, quality, and innovation across machine learning projects.

What are the key skills and qualifications needed to thrive in the staff machine learning engineer position, and why are they important?

To thrive as a Staff Machine Learning Engineer, you need deep expertise in machine learning algorithms, software engineering, data analysis, and typically a strong academic background in computer science or related fields. Experience with Python, TensorFlow, PyTorch, cloud platforms, and a track record of delivering production-level ML systems are crucial, as are advanced degrees or relevant certifications. Strong leadership, communication, and mentoring skills help you effectively guide teams and collaborate across departments. These competencies are essential for designing robust ML solutions, leading technical initiatives, and ensuring successful project delivery in complex organizational environments.

Do staff machine learning engineers get paid well?

Staff machine learning engineers typically earn high salaries due to their advanced skills, experience, and expertise in developing complex models and deploying AI solutions. Compensation often includes base salary, bonuses, and stock options, reflecting their seniority and impact within organizations.

What are the most commonly searched types of Staff Machine Learning Engineer jobs in Boston, MA?

The most popular types of Staff Machine Learning Engineer jobs in Boston, MA are:

What are popular job titles related to Staff Machine Learning Engineer jobs in Boston, MA?

For Staff Machine Learning Engineer jobs in Boston, MA, the most frequently searched job titles are:

Infographic showing various Staff Machine Learning Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 18% Part Time, 1% Temporary, and 4% Contract. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $107,912 per year, or $51.9 per hour.

Staff Engineer, Machine Learning Life Sciences

Inari

Cambridge, MA • On-site

$149 - $204/hr

Other

Medical, Dental, Vision, Retirement, PTO

Re-posted 28 days ago


Job description

About Inari... Inari is the SEEDesign™ company. We embrace the diversity and complexity of nature in every aspect of our business to drive innovation – to push the boundaries of what is possible. Through our unrivaled technology platform, Inari uses predictive design and advanced multiplex gene editing to develop step-change products. We are taking a nature positive approach to unlock the full potential of seeds that will transform the food system. The results will lead to more productive acres delivering value creation for farmers and a more sustainable future for our planet. Our success is dependent on great minds, collaborating to generate bright ideas and deliver exceptional outcomes. We have 200 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), as well as a product development site in West Lafayette, IN (USA). We’ve deliberately built a team that brings diversity of thought to all aspects of our business, to generate new ideas, approaches, and ways of operating. And we've intentionally combined experience with potential, bringing agriculture industry experts with the desire to innovate together with bright minds from academia, human therapeutics, software, and consulting.

About the role

Inari is seeking a Staff Machine Learning Engineer to join our AI Team in support of our mission of transforming agriculture through predictive design and advanced gene editing. This role will focus on delivering production-ready ML pipelines using existing models while also exploring new modeling approaches to advance our ability to drive step-change trait improvement in crops. In this role, you will bring established best practices for building, deploying, and maintaining ML systems, and effectively apply that expertise in a life sciences context. While life science experience is not a requirement, you are comfortable — or willing to become comfortable — working alongside biologists and reasoning about biological data. As a staff-level individual contributor, you will drive major workstreams with autonomy while collaborating closely with cross-functional teams of computational biologists, software engineers, and crop scientists. This role is based in our Cambridge, MA office and follows our flexible hybrid work model, with time on a weekly basis split between in-office and remote work. As a Staff ML Engineer, Life Sciences you will…

  • Build, deploy, and maintain production ML pipelines and infrastructure to serve predictions at scale, including model versioning, monitoring, and lifecycle management
  • Integrate ML systems with genomic, phenotypic, and biological data platforms using AWS and containerization technologies
  • Partner with computational and experimental biologists to contextualize heterogeneous biological data and drive research-critical modeling programs
  • Train and validate statistical and ML models; prototype new approaches and evaluate feasibility for production deployment
  • Implement integrations with strategic third-party tools, foundation models, and AI agents; stay current with ML research to identify applicable methods
  • Drive major workstreams autonomously while collaborating effectively with teammates and cross-functional stakeholders
  • Communicate technical results clearly across disciplines and contribute to technical decisions, code reviews, and engineering standards
You Bring…
  • Required Education & experience: MS or PhD in Computer Science, Engineering, Statistics, Mathematics, Computational Biology, or related field (or BS with equivalent experience); 6+ years of ML engineering experience with a demonstrated emphasis on production systems
  • Production ML: Proven ability to deploy, maintain, and monitor ML models and pipelines at scale
  • Python & frameworks: Advanced scientific Python (NumPy, Pandas, scikit-learn) and hands‑on experience with PyTorch and/or TensorFlow, including training and deploying neural networks
  • Cloud & MLOps: Experience with AWS (EC2, S3, SageMaker), containerization (Docker), experiment tracking (MLflow), and workflow orchestration (Airflow or equivalent)
  • Cross-disciplinary collaboration: Comfortable interfacing with biologists and life scientists, translating between biological and ML framings, and communicating technical results to diverse audiences
  • Ownership & drive: Track record of owning solutions and deliverables end‑to‑end — setting direction, aligning stakeholders, and seeing work through to impact — while remaining a collaborative and engaged team member
  • Strongly Preferred Life sciences & bioinformatics: Familiarity with biological data types (genomic, transcriptomic, proteomic), common file formats (FASTA, GFF, VCF, BAM), and sequence modeling methods applied to DNA/RNA/protein data
  • ML for biology: Awareness of current research in applying deep learning to biological sequences (e.g., genomic transformers, protein language models)
  • Network analysis: Experience with graph neural networks or network analysis tools (e.g., networkx) for modeling complex biological relationships (e.g., gene regulatory networks, protein‑protein interaction networks)

Inari pays competitively and rewards results. The salary range for this position is $148,530 - 204,250. Whether you are full‑time or part‑time, Inari provide three different components of pay – base, short‑term incentive, and long‑term equity along with a one‑time new hire stock option grant. That's rare! We also offer a comprehensive benefits package including both a Preferred Provider Network (PPO) and High Deductible Health Plan (HDHP) with a company‑funded health savings account (HSA), vision, dental, and several flexible spending accounts (FSA), a host of voluntary benefits, and a robust wellness program. In addition, Inari offers a 401k plan with a company matching and a flexible paid time off policy. Consistent with our commitment to pay transparency, salary range information is being disclosed. Please note that offers are based on the candidate's qualifications & experience as well as market demand.

  • Preferred Provider Network (PPO)
  • High Deductible Health Plan (HDHP) with company‑funded health savings account (HSA)
  • Vision
  • Dental
  • Several flexible spending accounts (FSA)
  • A host of voluntary benefits
  • A robust wellness program
  • 401k plan with company matching
  • Flexible paid time off policy

Inari is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Learn more about us: About Inari:

  • https://inari.com/about-us/
  • https://inari.com/multiplex-gene-editing-matters-for-the-population-the-planet-and-the-people-who-grow-our-food/
  • https://inari.com/the-promise-of-ai-in-plant-breeding-2/
  • https://www.cambridgeassociates.com/podcasts/agriculture/
  • https://inari.com/inari-repeats-as-agtech-company-of-the-year/
  • https://www.bloomberg.com/news/articles/2025-01-07/agtech-startup-inari-raises-equity-at-2-17-billion-valuation
  • https://inari.com/bbc-news-how-crops-are-being-disaster-proofed/
  • https://www.reuters.com/markets/commodities/australian-trial-gene-edited-wheat-aims-10-bigger-yields-2024-05-23/#:~:text=CANBERRA%2C%20May%2023%20(Reuters),and%20make%20farming%20more%20sustainable
  • https://www.youtube.com/watch?v=pJG-r3ob-n0

Job Applicant Privacy Notice: https://inari.com/wp-content/uploads/2024/09/Job-Applicant-Privacy-Notice.pdf

FOR U.S. CANDIDATES: Please note that we use the resume you submit with your application during our background check process. To ensure an efficient and accurate background verification, we kindly ask that you carefully review and accurately represent your work history, education and other relevant information on your resume. Any discrepancies or inaccuracies found during the background check may impact your candidacy for the position.

At Inari, we're driven to help transform the global food system to support the population, the planet and the people who grow our food. We're powered by a strong focus on camaraderie, professional development, and external collaboration with leaders of industry and academia, all of which allow us to forge personal connections that strengthen our teams. Our success is dependent on great minds, collaborating to generate bright ideas and deliver exceptional outcomes. We have over 200 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), as well as a product development site in West Lafayette, IN (USA). We’ve deliberately built a team that brings diversity of thought to all aspects of our business, to generate new ideas, approaches, and ways of operating. And we've intentionally combined experience with potential, bringing agriculture industry experts with the desire to innovate together with bright minds from academia, human therapeutics, software, and consulting.

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