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Sr Validation Engineer Jobs in California (NOW HIRING)

3B Staffing LLC

Senior Validation Engineer

Alameda, CA · On-site

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities: * Review/approve ...

New

3B Staffing LLC

Senior Validation Engineer

Alameda, CA · On-site

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities: * Review/approve ...

New

Syner-G

Sr. Validation Engineer

San Diego, CA · On-site

  • PTO

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Syner-G

Sr. Validation Engineer

San Diego, CA · On-site

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Syner-G

Sr. Validation Engineer

San Diego, CA · On-site

  • PTO

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Microsoft

Senior Validation Engineer

Mountain View, CA · On-site

$119K - $234K/yr

We are looking for a Senior Validation Engineer with expertise in one or more of the following validation domains : functional, electrical, high speed interfaces, memory, power/performance, debug/BU ...

New

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

Lonza

Senior Validation Engineer - CSV (OT)

Vacaville, CA · On-site

$93K - $155K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Paid Time Off The Senior Validation Engineer - CSV at Lonza will be responsible for leading and executing validation activities for manufacturing processes, equipment, computerized systems, and ...

Lonza

Senior Validation Engineer - CSV (OT)

Vacaville, CA · On-site

$93K - $155K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Paid Time Off The Senior Validation Engineer - CSV at Lonza will be responsible for leading and executing validation activities for manufacturing processes, equipment, computerized systems, and ...

Everpure

MTS - Senior Validation Engineer

Santa Clara, CA · On-site

$180K - $270K/yr

  • PTO

THE ROLE As a Validation Engineer (IC) on the Drive Qualification team, you will design and execute PCIe-focused validation and debug for Everpure SSDs. You'll own link and protocol test coverage ...

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

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Sr Validation Engineer information

See California salary details

$34

$63

$97

How much do sr validation engineer jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for sr validation engineer in California is $63.92, according to ZipRecruiter salary data. Most workers in this role earn between $51.01 and $72.60 per hour, depending on experience, location, and employer.

What are some common challenges a Sr validation engineer faces when managing multiple validation projects simultaneously?

A Sr Validation Engineer often manages several validation projects at once, which can present challenges such as coordinating timelines, ensuring compliance with regulatory standards, and balancing cross-functional communication. Keeping detailed documentation and staying organized are essential, as unexpected equipment issues or shifting project priorities may arise. Successful engineers proactively communicate with quality, manufacturing, and R&D teams to mitigate risks, maintain project momentum, and deliver results within required deadlines.

What is a Sr validation engineer?

Sr Validation Engineers are experienced professionals responsible for ensuring that products, systems, or processes meet regulatory standards and function as intended. They lead validation projects, develop protocols, oversee testing, and document results to confirm compliance with industry regulations, such as those from the FDA or ISO. Their work is essential in industries like pharmaceuticals, biotechnology, and manufacturing, where product quality and safety are critical. Senior validation engineers also mentor junior staff and help improve validation processes within their organizations.

What are the key skills and qualifications needed to thrive as a Sr validation engineer?

To thrive as a Sr Validation Engineer, you need a solid background in engineering or life sciences, extensive experience with validation protocols, and a strong understanding of regulatory standards such as FDA, GMP, or ISO. Expertise in using validation software, risk assessment tools, and familiarity with documentation management systems is typically required, along with certifications like Six Sigma or ASQ CQE being advantageous. Exceptional problem-solving abilities, attention to detail, and effective communication skills help you lead teams and interact with cross-functional departments. These competencies are crucial for ensuring products and processes meet compliance standards, maintain quality, and support organizational success.

What is the difference between Sr Validation Engineer vs Validation Engineer?

AspectSr Validation EngineerValidation Engineer
Required CredentialsBachelor's/Master's in Engineering, certifications like CQE or ASQ, experience in validation processesBachelor's in Engineering or related field, some certifications preferred, less experience required
Work EnvironmentPharmaceutical, biotech, or manufacturing industries; leading validation projectsSupporting validation tasks under supervision, often in similar industries
Employer & Industry UsageUsed by companies requiring compliance with FDA, ISO, or GMP standardsCommonly used in manufacturing and quality assurance roles

The main difference between a Sr Validation Engineer and a Validation Engineer lies in experience, responsibility, and expertise. The Sr Validation Engineer typically leads validation projects, has more advanced certifications, and plays a strategic role in compliance. Validation Engineers support validation activities and often work under supervision. Both roles are essential in regulated industries like pharmaceuticals and manufacturing, but the senior role involves greater leadership and technical oversight.

What are popular job titles related to Sr Validation Engineer jobs in California? For Sr Validation Engineer jobs in California, the most frequently searched job titles are:
What job categories do people searching Sr Validation Engineer jobs in California look for? The top searched job categories for Sr Validation Engineer jobs in California are:
What cities in California are hiring for Sr Validation Engineer jobs? Cities in California with the most Sr Validation Engineer job openings:
Sr Validation Engineer jobs near you
Infographic showing various Sr Validation Engineer job openings in California as of August 2026, with employment types broken down into 88% Full Time, 5% Part Time, 2% Temporary, and 5% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $132,962 per year, or $63.9 per hour.

Senior Validation Engineer

3B Staffing LLC

Alameda, CA • On-site

Full-time

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities:
  • Review/approve SDLC deliverables: MVP testing, FMEA, IQ, OQ, PQ, trace matrices, system releases.
  • Provide validation expertise for IT applications and ensure compliance readiness.
  • Collaborate with development teams to align deliverables with business and compliance standards.
  • Oversee CAPAs, change controls, and defect management.
Qualifications:
  • 7+ years in software validation and QA.
  • Proficient in GxP regulations, validation principles, and automated testing.
  • Experience with Salesforce, Veeva, and tools like JIRA, Tosca, ALM, and Confluence.
  • Knowledge of Agile and Waterfall methodologies.

Apply