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Sr Python Developer Jobs in Massachusetts (NOW HIRING)

Sonoma Consulting Inc.

Senior DevOps Engineer

Boston, MA

$141K - $181K/yr

TITLE : DevOps Engineer/Senior DevOps Engineer LOCATION : We are looking forcandidates in 1. Boston ... Experience coding or scripting with Shell, Ruby/JRuby, Perl, Python, Powershell, Java, Go, or Bash

Judge Group, Inc.

Senior AWS Developer

Quincy, MA · On-site

$54 - $64/hr

The Sr. AWS Developer's primary role is to support the design and development of a serverless ... AWS Lambda (Python runtime) * AWS Step Functions * API Gateway (REST/HTTP APIs) * Amazon Cognito

Medtronic

Sr. Software DevOps Engineer

Newton, MA · On-site

$142K - $183K/yr

As a Sr. Software DevOps Engineer, you will play a pivotal role in accelerating our software ... Proficient in languages such as Python, C++, Bash, or similar * Extensive experience with ...

Medtronic

Sr. Software DevOps Engineer

Newton, MA · On-site

$142K - $183K/yr

As a Sr. Software DevOps Engineer, you will play a pivotal role in accelerating our software ... Proficient in languages such as Python, C++, Bash, or similar * Extensive experience with ...

Saviance

Senior Java/AWS Engineer -with LIMS

Boston, MA · On-site

$135K - $178K/yr

They are seeking a skilled Senior Java/AWS Engineer -with LIMS to collaboratively solve complex ... Some Python programming is preferred Company : Saviance is a modern consulting firm providing a ...

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Sr Python Developer information

See Massachusetts salary details

$60.1K

$155.1K

$213K

How much do sr python developer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for sr python developer in Massachusetts is $155,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $132,700.00 and $178,600.00 per year, depending on experience, location, and employer.

What is a Sr Python Developer?

A Sr Python Developer is an experienced software engineer who specializes in designing, developing, and maintaining applications using Python. They are responsible for writing clean, efficient, and scalable code while also mentoring junior developers and collaborating with cross-functional teams. Their role often includes optimizing application performance, integrating third-party services, and ensuring best coding practices. Additionally, they may work with frameworks like Django or Flask and databases such as PostgreSQL or MongoDB to build robust backend systems.

What are the typical daily responsibilities of a Sr Python Developer?

As a Sr Python Developer, your daily tasks often include designing and coding complex features, reviewing code from team members, and troubleshooting bugs or performance issues. You may also lead technical discussions, contribute to architectural decisions, and collaborate closely with product managers, QA engineers, and other developers. Mentoring junior team members and staying up to date with best practices or new technologies is also a regular part of the role. This combination of hands-on engineering and leadership responsibilities ensures both the quality of the codebase and the continual growth of the team.

What are the key skills and qualifications needed to thrive in the Sr Python Developer position, and why are they important?

To thrive as a Sr Python Developer, you need expert proficiency in Python programming, strong problem-solving skills, and a solid background in computer science or related fields, often demonstrated by several years of relevant experience. Familiarity with frameworks like Django or Flask, version control systems such as Git, and sometimes certifications such as PCEP or PCAP are typically valued. Strong communication, leadership, and the ability to mentor junior developers are standout soft skills for this position. These combined proficiencies ensure that Sr Python Developers can build robust solutions, contribute to architectural decisions, and drive team success in complex technical environments.

What are popular job titles related to Sr Python Developer jobs in Massachusetts?

For Sr Python Developer jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Sr Python Developer jobs in Massachusetts look for?

The top searched job categories for Sr Python Developer jobs in Massachusetts are:

Sr Python Developer jobs near you
Infographic showing various Sr Python Developer job openings in Massachusetts as of August 2026, with employment types broken down into 1% Internship, 89% Full Time, 5% Part Time, and 5% Contract. Highlights an 76% Physical, 7% Hybrid, and 17% Remote job distribution, with an average salary of $155,055 per year, or $74.5 per hour.

Senior AI Engineer (Generative AI & Agentic Systems)

Pan.bio

Boston, MA • On-site

$180 - $260/hr

Other

Posted yesterday

New

Job description

Now Hiring Machine Learning AI Engineering Priority Hire

Senior AI Engineer (Generative AI & Agentic Systems)About Pan.Bio

Pan.Bio is building an AI-native platform that helps scientists and clinicians analyze complex biomedical data, automate research workflows, and accelerate discovery. Our products combine bioinformatics, cloud computing, and Generative AI to transform how researchers interact with data, knowledge, and scientific workflows.

We are looking for a Senior AI Engineer with strong machine learning and data science fundamentals to help build the next generation of AI-powered capabilities across our platform.

What You'll Do
  • Design, build, and deploy production-grade AI systems and intelligent applications.
  • Develop AI agents, agent skills, MCP integrations, RAG systems, and workflow automation solutions.
  • Build reusable AI capabilities that can be shared across products and use cases.
  • Evaluate, monitor, and improve AI systems using rigorous experimentation and data-driven decision making.
  • Collaborate closely with software engineers, bioinformaticians, and product teams to solve real-world scientific and healthcare challenges.
  • Stay current with advances in Generative AI and help shape our technical roadmap.
What We're Looking For
  • 4+ years of experience in AI/ML Engineering, Data Science, Applied AI, or a related field.
  • Strong foundation in machine learning, statistics, experimentation, and data analysis.
  • Strong Python programming and software engineering skills.
  • Experience building and deploying production AI/ML systems in cloud environments (GCP preferred).
  • Hands-on experience with LLMs, reasoning models, tool calling, structured outputs, context engineering, and AI evaluation.
  • Experience building agentic AI systems, including AI agents, agent skills, MCP integrations, RAG, and workflow automation.
  • Familiarity with the full ML lifecycle, from experimentation and evaluation to deployment and monitoring.
  • Ability to thrive in a fast-paced startup environment with high ownership and autonomy.
Nice to Have

Not blockers, but they'll make your application stand out.

  • Experience with multi-agent systems, agent orchestration, or AI platform engineering.
  • Experience with AI observability, guardrails, and governance.
  • Experience with Docker, Kubernetes, MLOps, and CI/CD.
  • Background in bioinformatics, genomics, healthcare, life sciences, or scientific computing.
Why Join Pan.Bio?
  • Build cutting-edge AI products at the intersection of Generative AI and life sciences.
  • Work on challenging problems with real-world scientific and healthcare impact.
  • Join a small, experienced team with significant ownership and influence over product direction.
  • Help shape the future of AI-powered scientific discovery.
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