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Sr Cra Jobs (NOW HIRING)

Senior CRA - Oncology - Midwest ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

Senior CRA

Chicago, IL ยท On-site +1

Senior CRA - Oncology - Midwest ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

Senior CRA - Oncology - Midwest ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

As Senior CRA, you will own site monitoring across CoMind's clinical programme, with responsibility spanning on-site and remote visits, in-house operations support, and study oversight. This is a ...

New

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Durham, NC ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Indianapolis, IN ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

San Francisco, CA ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Indianapolis, IN ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Durham, NC ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Scottsdale, AZ ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Sacramento, CA ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Sacramento, CA ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CRA 2/Senior CRA

Chicago, IL ยท On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

CONTRACT SENIOR CRA/CRA II (Home-based anywhere in the U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

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Sr Cra information

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$25K

$80.3K

$163.5K

How much do sr cra jobs pay per year?

As of Jun 10, 2026, the average yearly pay for sr cra in the United States is $80,287.00, according to ZipRecruiter salary data. Most workers in this role earn between $41,500.00 and $103,000.00 per year, depending on experience, location, and employer.

What are Senior Clinical Research Associates (Sr CRA)?

Senior Clinical Research Associates (Sr CRAs) are experienced professionals who oversee and monitor clinical trials to ensure they comply with regulatory requirements, protocols, and good clinical practice guidelines. They typically manage multiple study sites, conduct site visits, and act as a primary point of contact between the study sponsor and clinical sites. Sr CRAs also mentor junior CRAs, resolve complex issues, and ensure high-quality data collection and reporting. Their work is essential in bringing new drugs and medical devices to market safely and efficiently.

What is the difference between Sr Cra vs Clinical Research Associate?

AspectSr CraClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trialsBachelor's degree, entry-level or some experience
Work EnvironmentSenior-level monitoring, site managementMonitoring sites, data collection
Employer & Industry UsagePharmaceutical companies, CROsPharmaceutical companies, CROs
Common Search & ComparisonHigher responsibility, leadership rolesEntry to mid-level monitoring

The main difference between a Sr Cra and a Clinical Research Associate is the level of experience and responsibility. A Sr Cra typically has more experience, handles complex site management, and may oversee other CRAs. In contrast, a Clinical Research Associate is often in an entry or mid-level role focused on site monitoring and data collection. Both roles are essential in clinical trials and are commonly found in pharmaceutical companies and CROs.

What are the key skills and qualifications needed to thrive as a Senior Clinical Research Associate (Sr CRA), and why are they important?

To thrive as a Sr CRA, you need in-depth knowledge of clinical trial protocols, Good Clinical Practice (GCP) guidelines, and relevant regulatory requirements, typically backed by a degree in life sciences and significant monitoring experience. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications like ACRP or SOCRA are highly valued. Strong attention to detail, effective communication, and problem-solving skills distinguish top performers in this role. These skills ensure protocols are followed, data integrity is maintained, and studies are completed efficiently and compliantly.

Is it hard to get a CRA job?

Securing a Senior Clinical Research Associate (CRA) position can be competitive due to the specialized skills and experience required, such as knowledge of clinical trial regulations and monitoring techniques. Candidates often need a relevant degree, industry certifications, and prior experience in clinical research to improve their chances.

What are some typical challenges faced by a Senior Clinical Research Associate (Sr CRA) when managing multiple clinical trial sites?

Senior Clinical Research Associates often juggle the oversight of several trial sites, which can pose challenges such as coordinating site schedules, ensuring consistent protocol compliance, and maintaining effective communication with site staff. Balancing documentation accuracy, regulatory requirements, and timely reporting is also crucial. Successful Sr CRAs develop strong organizational skills and proactive problem-solving approaches to address issues like site recruitment delays or data discrepancies, while also leveraging collaboration with project managers and clinical teams to keep trials on track.
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Senior CRA

Senior CRA

Icon plc

Indianapolis, IN โ€ข On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 28 days ago


Job description

Senior CRA - Oncology - Midwest

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


What You Will Be Doing:

  • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.

  • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.

  • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.

  • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.

  • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Your Profile:

  • Advanced degree in a relevant field such as life sciences, nursing, or medicine.

  • Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.

  • Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.

  • Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.

  • Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.

  • Five years of CRA experience with oncology monitoring experience

  • Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

  • Must be located in the US Midwest


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Salary Range

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Are you a current ICON Employee? Please click here to apply