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Precise Systems

In-Vitro Toxicologist

Aberdeen, MD · On-site

$76K - $86K/yr

... spheroid/MPS architectures (i.e. organ chip technologies) for use in toxicological assessments and research method development. * Research efforts shall include determination of novel biomarkers of ...

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What are the key skills and qualifications needed to thrive as a Spheroid, and why are they important?

I'm sorry, but 'Spheroid' is not a recognized professional occupation, so I cannot provide a relevant answer.

What is the difference between Spheroid vs Geotechnical Engineer?

AspectSpheroidGeotechnical Engineer
Required CredentialsBachelor's in Geology, Civil Engineering, or related field; certifications varyBachelor's or Master's in Civil or Geotechnical Engineering; often licensed
Work EnvironmentField surveys, laboratory testing, data analysisSite investigations, design, analysis, report writing
Industry UsageGeotechnical investigations, environmental assessmentsFoundation design, slope stability, soil testing

While Spheroid specialists focus on specific geological formations and data analysis, Geotechnical Engineers apply engineering principles to design foundations and assess soil stability. Both roles often collaborate in construction projects but differ in their core focus and qualifications.

What are the typical daily responsibilities of a Spheroid Engineer in a manufacturing environment?

As a Spheroid Engineer, your daily tasks often include monitoring the production of spheroidal components, analyzing quality control data, and troubleshooting process issues to optimize yield and performance. You’ll collaborate closely with production operators, quality assurance teams, and maintenance staff to ensure that equipment runs efficiently and products meet specifications. Regular responsibilities also involve documenting process changes, participating in team meetings to discuss continuous improvement, and staying updated on industry best practices to implement innovative solutions.

What are spheroids in a professional or scientific context?

In a scientific or biomedical context, spheroids are three-dimensional cell culture systems that mimic the structure and function of tissues in the human body. They are often used in research to study cell behavior, drug responses, and disease models, especially in cancer research. Spheroids provide more realistic results compared to traditional two-dimensional cell cultures because they better mimic the natural environment of cells. Researchers use them to test new drugs, understand disease mechanisms, and explore tissue engineering applications.
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Infographic showing various Spheroid job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 100% Physical job distribution.

Scientist ll - SR Senior Scientist Ex Vivo & 3D Model Assays

WuXi Biologics

Natick, MA • On-site

$73K - $117K/yr

Full-time

Posted yesterday

Job description

Title: Scientist ll - Senior Scientist Ex Vivo & 3D Model Assays
Location: Natick, MA
Job Summary
We are seeking a highly motivated Scientist with hands-on expertise in ex vivo immune assays, 3D spheroid, and organoid-based platforms to support our preclinical drug discovery efforts. The successful candidate will have a PhD with 2-3 yrs or Master's degree with 5-6 years of relevant industry experience and will play a key role in evaluating the biological activity and mechanism of novel therapeutic candidates across oncology, autoimmune, and inflammatory disease areas.
This role is ideal for a scientist passionate about translating complex biology into meaningful data using patient-relevant assay systems
Job Responsibilities:
  • Design, execute, and analyze ex vivo assays using human PBMCs, tumor digests, or tissue-derived immune cells.
  • Develop and implement 3D spheroid and organoid-based co-culture systems, including tumor-immune or stroma-immune models.
  • Perform high-content immunophenotyping and functional readouts using multi-color flow cytometry, cytokine profiling (MSD, ELISA, Luminex), and live-cell imaging.
  • Support pharmacodynamic, MOA, and efficacy studies for biologics, TCEs, and other immunomodulatory agents.
  • Work with human biospecimens (e.g., tumor tissue, blood, ascites) and maintain compliance with biosafety and sample handling protocols.
  • Maintain detailed records, present findings at team meetings, and contribute to internal documentation and publications.

Qualifications:
  • PhD in Immunology, Cell Biology, Pharmacology, or a related field with 2-3 years of hands-on industry experience, or a Master's degree with 4-5 years of relevant experience in a biotechnology or pharmaceutical setting.
  • Proven expertise in ex vivo immune cell assays, primary cell culture, and immune cell functional analysis.
  • Experience with 3D cell culture systems such as tumor spheroids, organoids, or co-culture models.
  • Strong skills in flow cytometry (data acquisition and analysis), cytokine assays, and viability/proliferation platforms.
  • Familiarity with handling human tissue samples and BSL-2 laboratory practices.
  • Excellent organizational skills, attention to detail, and the ability to independently troubleshoot and optimize assays.
  • Strong team player with effective communication and presentation skills.

Preferred Qualifications:
  • Experience applying 3D culture platforms to immune-oncology, autoimmune disease, or ither disease area.
  • Proficiency in flow cytometry software (e.g., FlowJo), imaging platforms (e.g., Incucyte), and analysis tools (e.g., GraphPad Prism).
  • Knowledge of T cell biology, myeloid interactions, or tumor microenvironment.
  • Familiarity with antibody-based therapeutic formats, including T cell engagers, ADCs or bispecifics.

The anticipated pay range for this position is $73,000 - $117,000
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

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