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Spatial Transcriptomics Jobs in Alabama (NOW HIRING)

Tuskegee University

Perform high-quality computational analysis of next-generation sequencing (NGS) data, including short and long-read whole-genome, whole-exome, RNA-seq, and spatial transcriptomics datasets. * Develop ...

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Spatial Transcriptomics information

What is spatial transcriptomics?

Spatial transcriptomics is an advanced technique that allows scientists to measure gene expression within the spatial context of tissue samples. Unlike traditional RNA sequencing, which loses information about where each gene is expressed, spatial transcriptomics preserves the physical location of gene activity in tissues. This helps researchers better understand how cells function within their native environments and interact with neighboring cells, which is especially valuable in fields like cancer research, neuroscience, and developmental biology. The method combines microscopy, molecular biology, and computational analysis to produce detailed maps of gene expression.

What are some common challenges faced by professionals working in spatial transcriptomics, and how can they be addressed?

Professionals in spatial transcriptomics often encounter challenges related to handling large, complex datasets and integrating spatial information with gene expression data. Ensuring high-quality sample preparation and mastering advanced imaging or sequencing technologies are also frequent hurdles. These challenges can be addressed by collaborating closely with multidisciplinary teams—including bioinformaticians, molecular biologists, and imaging specialists—and staying up-to-date with the latest software tools and protocols. Continuous learning and effective communication within the team are key to overcoming technical and analytical obstacles in this rapidly evolving field.

What are the key skills and qualifications needed to thrive as a Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a life science field. Familiarity with spatial transcriptomics platforms (such as 10x Genomics Visium), next-generation sequencing (NGS) technologies, and data analysis tools like R or Python is essential. Strong problem-solving skills, attention to detail, and effective communication are important soft skills for collaborating on interdisciplinary research projects. These skills and qualities are crucial for generating high-quality spatial gene expression data and translating findings into meaningful biological insights.
What are popular job titles related to Spatial Transcriptomics jobs in Alabama? For Spatial Transcriptomics jobs in Alabama, the most frequently searched job titles are:
What job categories do people searching Spatial Transcriptomics jobs in Alabama look for? The top searched job categories for Spatial Transcriptomics jobs in Alabama are:
Spatial Transcriptomics jobs near you
Infographic showing various Spatial Transcriptomics job openings in Alabama as of July 2026, with employment types broken down into 67% Full Time, 27% Part Time, 1% Temporary, and 5% Contract. Highlights an 75% Physical, 1% Hybrid, and 24% Remote job distribution.
Postdoctoral

Postdoctoral

The University of Alabama at Birmingham

Birmingham, AL • On-site

$45K - $62K/yr

Other

Posted 20 days ago

University Of Alabama At Birmingham rating

7.7

Company rating: 7.7 out of 10

Based on 44 frontline employees who took The Breakroom Quiz

228th of 555 rated colleges and universities

Job description

Position Information
Job Title Postdoctoral Department Name 392303040 Neuropathology School/College Academic Joint Departments Job Description
The Comba Laboratory in the Department of Pathology, Division of Neuropathology, at the University of Alabama at Birmingham (UAB) is seeking a highly motivated and creative postdoctoral researcher to join our multidisciplinary team investigating the mechanisms of glioblastoma (GBM) progression and therapeutic resistance.
Our research focuses on understanding how interactions between glioma cells and the brain microenvironment drive tumor invasion, recurrence, and treatment resistance. We combine cancer biology, neuroscience, extracellular matrix biology, spatial transcriptomics, advanced imaging, and immunology to identify novel therapeutic strategies for malignant brain tumors.
The successful candidate will have access to a highly collaborative research environment and state-of-the-art technologies, including patient-derived glioblastoma models, orthotopic mouse models, 3D organotypic brain slice cultures, live-cell imaging approaches, multiplex immunofluorescence, RNAscope, spatial transcriptomics (10x Visium HD, Xenium), flow cytometry, and bioinformatics analyses.
The Comba Laboratory collaborates extensively with investigators across the UAB O'Neal Comprehensive Cancer Center, the Department of Neurosurgery, the Department of Pathology, and national and international leaders in neuro-oncology, extracellular matrix biology, neuroscience, and spatial biology. 
Applications containing a cover letter and current curriculum vitae should be sent to: Andrea Comba via email: andraecomba@uabmc.edu  
Required Qualifications
PostdocCandidates should possess a Ph.D., M.D., or equivalent degree in cancer biology, neuroscience, molecular biology, genetics, computational biology, or related biomedical fields. Candidates should have experience with cell culture, animal models, molecular biology, imaging, or computational analysis. Experience with 3D organoids or slices models, confocal imaging and Bioinformatics analysis is desirable. We are seeking individuals who are enthusiastic and collaborative.
 Interested candidates should submit CV, a cover letter detailing research experience and contact details of three references to: Andrea Comba via email: andraecomba@uabmc.edu  
Preferred Qualifications
Posting Detail Information
Posting Number PF1041P Open Date 06/25/2026 Close Date Open Until Filled Yes Nondiscrimination Statement
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
Special Instructions for the Position Pre-employment Background Check
A pre-employment background check investigation is performed on candidates selected for employment.
About University of Alabama at Birmingham
The University of Alabama at Birmingham is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 250 postdocs are currently training in a variety of disciplines, including but not limited to engineering, medicine, natural sciences & mathematics, public health, and optometry.
The UAB Office of Postdoctoral Education and the UAB Postdoc Association work together to develop career opportunities that enhance and define the training experience for all postdoctoral scholars at UAB.
Because of its commitment to the success of postdoctoral fellows, UAB ranks consistently as one of the top locations among US universities for training postdoctoral scholars.
 
Department of Pathology
University of Alabama at Birmingham

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The University of Alabama at Birmingham is the heartbeat of Birmingham and an integral medical leader in the Southeast. The Birmingham campus is within walking distance of some of the best parks, entertainment, and dining in the region. UAB's three regional campuses expand their academic reach and responsibilities in addition to educating physicians in rural and underserved areas of the state. UAB is experiencing major and sustained investment and growth, due both to its exceptional research faculty and its culture of collaboration. Through concerted and strategic investments in its clinical and research enterprise, UAB has undergone an amazing transformation in the past five years and has strengthened its status and reputation as a leader in medical training, biomedical discovery, innovation, and patient care.

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Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Birmingham, AL, US

Year founded

1859

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