Software Engineer Biology Jobs in Tennessee (NOW HIRING)

The Northcott Lab in the Center of Excellence in Neuro‑Oncology Sciences (CENOS) at St. Jude Children’s Research Hospital is seeking a highly motivated Bioinformatics Research Scientist or Senior Bioinformatics Research Scientist.

• Provide research support and deliver high‑quality results by formulating efficient analytical approaches with available data.
• Deliver data files, document the analytical process, and may participate in manuscript preparation at project’s conclusion.
• Assist with establishing and documenting protocols or best practices for common research tasks, and formulate analytical plans.
• Assist in evaluation and testing of new methods and technologies, and contribute ideas to automate or improve existing analysis methods.
• Implement improvements or work with others to do so.
• Participate in departmental developmental projects and interdepartmental team projects.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintain regular and predictable attendance.

• A PhD in bioinformatics, computational biology, data science or a related field.
• Experience analyzing single‑cell/nucleus RNA‑seq, spatial transcriptomics, RNA‑seq, ATAC‑seq, ChIP‑seq/CUT‑RUN, and DNA methylation.
• Strong CV with publications involving cancer genomics, epigenomics, single‑cell, spatial ‘omics, machine learning, and AI.
• Experience interpreting and visualizing human genomics datasets generated by high‑throughput sequencing platforms (short‑read Illumina, long‑read PacBio and Oxford Nanopore).
• Proficiency in R and Python, preferably in a high‑performance computing (HPC) environment.
• Proficiency with workflow management systems (e.g., Nextflow or Snakemake) and version control (e.g., Git).
• Extensive expertise in data integration and harmonization.
• Proven problem‑solving skills and collaborative nature in a fast‑paced environment.
• Excellent communication and presentation skills.

• Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check.
• Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis.
• Act as a liaison between end‑users, software developers, system designers, and different departments.
• Establish protocols or best practices for common research tasks and SOPs, evaluate products and solutions and integrate solutions.
• Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection.
• Develop programs to assist in the analysis of data within the databases.
• Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintain regular and predictable attendance.

• Proficiency in at least one programming or scripting language and one statistical package, with R preferred.

• Bachelor’s degree in bioinformatics, cheminformatics, statistics/computer‑science (with a background in biological sciences or chemistry) or related field (Master’s or PhD preferred).
• Bachelor’s degree with 7+ years of post‑degree work in bioinformatics, cheminformatics, statistics/computer‑science (with a background in biological sciences or chemistry).
• Master’s degree with 5+ years of post‑degree experience (or) PhD with 2+ years of relevant post‑degree experience.
• Bioinformatics Research Scientist specific requirement: Bachelor’s degree with 6+ years of post‑degree work; Master’s degree with 4+ years of post‑degree experience (or) PhD with no experience. Additionally, proficiency in at least one programming or scripting language and one statistical package, with R preferred.

A reasonable estimate of the current salary range is $104,000–$186,160 per year for the role of Bioinformatics Research Scientist / Senior Bioinformatics Research Scientist – Northcott Lab, CENOS.

St. Jude is an Equal Opportunity Employer. St. Jude Children’s Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.