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Dr. Lockett is an Assistant Professor in the Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine. Her research interests are to investigate the etiology of the vascular abnormalities that mediate vascular remodeling in pulmonary arterial hypertension (PAH), and to identify molecules or pathways to target for therapeutic intervention. Her lab is specifically interested in identifying the role of maladaptive mitochondrial function which may alter metabolic pathways to promote the pathogenesis of PAH. We made the novel discovery that the evolutionarily conserved stress response, the mitochondrial unfolded protein response (UPRmt), promotes vascular remodeling in preclinical models of PAH and promotes a hyper-proliferative phenotype in pulmonary artery smooth muscle and endothelial cells.
Job Summary
This position involves working with tissues from animals as well as preforming cell culture. Common methodology in the lab include molecular biology techniques involving protein and RNA isolation, Western blotting, qPCR, and gene silencing or ectopic expression.
General Responsibilities

• Performs a wide variety of complex experiments and reports results.
• Keeps organized analytical data of performed experiments.
• Provides support for equipment maintenance as needed.
• Acts as a liaison to students and laboratory personnel for training.
• Maintains laboratory supply requisition and management.
• May train junior-level staff.
• May help plan experiments or short-term goals.

Qualifications
Combinations of related education and experience may be considered. Education beyond the minimum required may be substituted for work experience. Work experience beyond the minimum required may be substituted for education.
EDUCATION
Required

• Bachelor's degree in science or related field.

WORK EXPERIENCE
Preferred

• Experience with cell culture and aseptic technique.

SKILLS
Required

• Proficient written and verbal communication skills.
• Maintains a high degree of professionalism.
• Demonstrates time management and priority setting skills.
• Demonstrates a high commitment to quality.
• Possesses flexibility to work in a fast paced, dynamic environment.
• Highly thorough and dependable.

Working Conditions / Demands
The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The role requires the ability to move objects weighing up to 25 pounds and will occasionally work near moving mechanical parts. The person in this role must be able to perform the essential functions with or without an accommodation.
Work Location
IU Indianapolis campus
Advertised Salary
$38,000 to $43,000 per year based on education and experience.
Benefits Overview
For full-time staff employees, Indiana University offers a wide array of benefits including:

• Comprehensive medical and dental insurance
• Health savings account with generous IU contributions
• Healthcare and dependent care flexible spending accounts
• Basic group life insurance paid by IU
• Voluntary supplemental life, long-term disability, critical illness, and supplemental accidental death & dismemberment insurance
• Base retirement plan with generous IU contributions, subject to vesting
• Voluntary supplemental retirement plan options
• Tuition subsidy for employees and family members taking IU courses
• 10 paid holidays plus a paid winter break each year
• Generous paid time off plans
• Paid leave for new parents and IU-sponsored volunteer events
• Employee assistance program (EAP)

Learn more about our benefits by reviewing the IU Benefit Programs Brochure .
Job Classification
Career Level: Intermediate
FLSA: Nonexempt
Job Function: Research
Job Family: Research Analysis
Click here to learn more about Indiana University's Job Framework.
Posting Disclaimer
This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.
If you wish to include a cover letter, you may include it with your resume when uploading attachments.
Equal Employment Opportunity
Indiana University is an equal opportunity employer and provider of ADA services and prohibits discrimination in hiring. See Indiana University Notice of Non-Discrimination here which includes contact information .
Campus Safety and Security
The Annual Security and Fire Safety Report, containing policy statements, crime and fire statistics for all Indiana University campuses, is available online . You may also request a physical copy by emailing IU Public Safety at iups@iu.edu or by visiting IUPD.
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