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Single Cell Spatial Transcriptomics Jobs in Needham, MA

In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company ® , adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a ...

Senior Scientist

Newton, MA · On-site

$100.40K - $137.10K/yr

Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE). * Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

Senior Scientist

Newton, MA · On-site

$100.40K - $137.10K/yr

Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE). * Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

Senior Scientist

Newton, MA · On-site

$100.40K - $137.10K/yr

Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE). * Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

Senior Scientist

Newton, MA · On-site

$100.40K - $137.10K/yr

Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE). * Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

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Single Cell Spatial Transcriptomics information

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How much do single cell spatial transcriptomics jobs pay per hour?

As of Jun 4, 2026, the average hourly pay for single cell spatial transcriptomics in Needham, MA is $23.58, according to ZipRecruiter salary data. Most workers in this role earn between $18.32 and $29.57 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Single Cell Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Single Cell Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree (PhD or MSc) in a relevant field. Familiarity with high-throughput sequencing platforms, spatial transcriptomics technologies (like 10x Genomics Visium or NanoString GeoMx), and data analysis tools such as R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating in multidisciplinary teams. These skills and qualities are vital for generating reliable insights into cellular function and spatial organization, which drive innovative research and discovery.

What are some typical challenges faced by professionals working in Single Cell Spatial Transcriptomics, and how can they be addressed?

Professionals in Single Cell Spatial Transcriptomics often encounter challenges related to handling large, complex data sets and integrating spatial information with single-cell transcriptomic profiles. These tasks demand strong computational skills and close collaboration with bioinformaticians and other researchers. Effective communication within interdisciplinary teams is essential to ensure experimental design aligns with downstream analysis needs. Staying updated with rapidly evolving technologies and best practices also helps professionals overcome technical hurdles and produce reliable, high-impact results.

What is single cell spatial transcriptomics?

Single cell spatial transcriptomics is a cutting-edge technique that allows researchers to analyze gene expression in individual cells while preserving their spatial location within a tissue. This method combines the high-resolution insights of single-cell RNA sequencing with spatial information, enabling scientists to understand how cells interact and organize within their native environments. It is widely used in biomedical research to study tissue architecture, disease mechanisms, and cellular heterogeneity.
What job categories do people searching Single Cell Spatial Transcriptomics jobs in Needham, MA look for? The top searched job categories for Single Cell Spatial Transcriptomics jobs in Needham, MA are:
What cities near Needham, MA are hiring for Single Cell Spatial Transcriptomics jobs? Cities near Needham, MA with the most Single Cell Spatial Transcriptomics job openings:
Infographic showing various Single Cell Spatial Transcriptomics job openings in Needham, MA as of May 2026, with employment types broken down into 4% Locum Tenens, 95% Full Time, and 1% Part Time. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $49,045 per year, or $23.6 per hour.
Postdoctoral Associate, Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian ...

Postdoctoral Associate, Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian ...

Boston University

Boston, MA • On-site

$70K/yr

Full-time

Posted 25 days ago


Boston University rating

7.9

Company rating: 7.9 out of 10

Based on 51 frontline employees who took The Breakroom Quiz

174th of 532 rated colleges and universities


Job description

Our laboratory invites applications for a postdoctoral associate focused on defining the molecular and cellular mechanisms by which bacterial infections drive lymphatic vessel dysfunction and lymphedema progression.

The successful candidate will contribute to a multidisciplinary project employing the following methods:

  1. Characterization of molecular and cellular perturbations caused by S. aureus strains using single-cell transcriptomics and lineage tracing in murine models of cutaneous infection and lymphatic vessel dysfunction.
  2. Delineation of infection-associated signaling cascades and testing the efficacy of pharmacological agents to restore contractile function of lymphatic vessels.
  3. Evaluation of the impact of S. aureus toxins on lymphatic vessel dynamics through high-resolution functional imaging.
  4. Investigation of targeted inhibition of S. aureus toxins on lymphatic function and host antimicrobial immunity in vivo to determine protective potential against recurrent infections.

Responsibilities

The postdoctoral associate will spend at least 80% of their time on research activities, including:

  1. Design and execution of murine infection models and assessment of lymphatic vessel function.
  2. Performance of single-cell RNA sequencing, lineage tracing, and high-resolution calcium imaging experiments.
  3. Analysis and interpretation of transcriptomic, imaging, and functional data.
  4. Testing pharmacological interventions and bacterial toxin inhibitors in vivo.
  5. Collaboration with clinical and translational research teams.
  6. Co-authoring manuscripts, presenting findings at scientific conferences, and contributing to grant preparation.

The remaining 20% may include:

  1. Mentoring graduate students and research assistants.
  2. Participating in laboratory meetings, journal clubs, and institutional seminars.
  3. Contributing to manuscript and grant writing efforts.

Appointment Details

Duration: Three years, with possibility of extension based on performance and funding
Salary: $70K


Required Skills

We seek candidates with expertise in vascular biology, immunology, microbiology, or related fields. Strong background in one or more of the following areas is required:

  • Experience with murine infection models, particularly cutaneous or soft tissue infection models.
  • Proficiency in functional imaging techniques such as intravital imaging
  • Familiarity with single-cell RNA sequencing, bioinformatics analysis, or lineage tracing approaches.
  • Experience with vessel isolation, ex vivo functional assays, or vascular smooth muscle cell biology.

Candidates with expertise in bacterial pathogenesis, toxin biology, host-pathogen interactions, or pharmacological intervention studies are especially encouraged to apply. The ideal candidate will be comfortable working at the interface of microbiology, vascular biology, and immunology and conducting hypothesis-driven research with translational implications.

APPLICATION INSTRUCTIONS: 

Email a Curriculum Vitae and a cover letter explaining your research interests to Dennis Jones, PhD, djones1@bu.edu. 

We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, natural or protective hairstyle, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, pregnancy or pregnancy-related condition, or because of marital, parental, or veteran status. We are a VEVRAA Federal Contractor.


Required Experience

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About Boston University

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Boston University is an international, comprehensive, private research university, committed to educating students to be reflective, resourceful individuals ready to live, adapt, and lead in an interconnected world. Boston University is committed to generating new knowledge to benefit society. We remain dedicated to our founding principles: that higher education should be accessible to all and that research, scholarship, artistic creation, and professional practice should be conducted in the service of the wider community—local and international. These principles endure in the University’s insistence on the value of diversity, in its tradition and standards of excellence, and in its dynamic engagement with the City of Boston and the world. Boston University comprises a remarkable range of undergraduate, graduate, and professional programs built on a strong foundation of the liberal arts and sciences. With the support and oversight of the Board of Trustees, the University, through our faculty, continually innovates in education and research to ensure that we meet the needs of students and an ever-changing world.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Boston, MA, US

Year founded

1839

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