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Single Cell Core Jobs (NOW HIRING)

MD Anderson

Research Assistant II - Leukemia

Houston, TX · On-site

$21.63 - $27.16/hr

... core facilities Support single-cell mass cytometry including antibody conjugation, titration, panel design, staining, barcoding, and data analysis using cytofkit, OMIQ, or similar pipelines ...

University of Michigan

RESEARCH FELLOW

Ann Arbor, MI · On-site

Core activities include cell-type-specific e/caQTL mapping in single-nucleus multi-omic data (snRNA-seq and snATAC-seq), colocalization and fine-mapping against T2D and related trait GWAS, Mendelian ...

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How much do single cell core jobs pay per hour?

As of Jun 4, 2026, the average hourly pay for single cell core in the United States is $21.64, according to ZipRecruiter salary data. Most workers in this role earn between $16.83 and $27.16 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Single Cell Core specialist, and why are they important?

To thrive as a Single Cell Core specialist, you need a strong background in molecular biology, genomics, and experience with single-cell sequencing techniques, often supported by an advanced degree in a life science field. Familiarity with technical tools such as flow cytometry, next-generation sequencing platforms, and data analysis software like Seurat or Cell Ranger is essential. Strong problem-solving abilities, attention to detail, and effective communication are key soft skills for collaborating with researchers and ensuring high-quality results. These competencies are crucial for generating reliable data, facilitating cutting-edge research, and advancing scientific discoveries in the field.

What are some common challenges faced by professionals working in a Single Cell Core facility, and how can new team members prepare for them?

Professionals in a Single Cell Core facility often encounter challenges such as troubleshooting complex instrumentation, managing large volumes of high-dimensional data, and ensuring sample quality throughout the workflow. New team members can prepare by developing strong technical skills in single cell platforms (like 10x Genomics or Fluidigm), familiarizing themselves with bioinformatics tools, and cultivating effective communication with researchers to understand experiment goals. Working collaboratively within a multidisciplinary team and staying current with emerging single cell technologies will also help overcome these challenges and contribute to the core’s success.

What is a Single Cell Core?

A Single Cell Core is a specialized facility within a research institution that provides expertise, equipment, and services for single-cell genomics and related technologies. These cores support researchers in isolating, processing, and analyzing individual cells to better understand cellular heterogeneity in complex tissues. Services may include single-cell RNA sequencing, library preparation, data analysis, and consultation. Single Cell Cores are essential for advancing research in fields such as cancer biology, immunology, and developmental biology.

What is the difference between Single Cell Core vs Single Cell Technician?

AspectSingle Cell CoreSingle Cell Technician
CredentialsTypically requires a bachelor's degree in biology, biotechnology, or related fieldsUsually requires a similar degree or certification in laboratory techniques
Work EnvironmentResearch laboratories, biotech companies, academic institutionsLaboratories, research facilities, biotech companies
Job FocusProviding core services for single cell analysis, data processing, and sample preparationPerforming technical procedures, sample handling, and data collection

The Single Cell Core generally refers to a facility or service providing specialized single cell analysis support, while a Single Cell Technician is an individual performing technical tasks within that environment. Both roles require similar educational backgrounds and work in comparable settings, but the Core often oversees multiple technicians and manages core services.

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Single Cell Core jobs near you

Research Associate Assay Development

CS Genetics Ltd

Pleasanton, CA • On-site

Full-time

Posted 14 days ago

Job description

Salary:

We are seeking a highly motivated Research Associate (25 years of experience) to support and accelerate assay development efforts. This role will work closely with other members of the Product Development team to execute, optimize, and characterize single-cell workflows and reagents.

This is a hands-on laboratory role ideal for someone who thrives in a fast-paced startup environment and wants to contribute meaningfully to building robust, scalable genomic products.


Key Responsibilities

  • Execute single-cell assay development experiments under the direction of senior scientists.
  • Prepare and characterize reagents used in single-cell workflows (e.g., enzymes, buffers, primers, beads, barcoding reagents).
  • Perform core molecular biology techniques including nucleic acid manipulation, reverse transcription, PCR/qPCR, ligation, enzymatic reactions, and NGS library preparation.
  • Design and execute optimization experiments using structured experimental design (DOE) approaches to evaluate assay parameters and reagent formulations.
  • Prepare and test buffer and reagent formulations and characterize their performance in assay workflows.
  • Run assays and optimization experiments using liquid-handling automation platforms (e.g., Agilent Bravo) and assist in adapting workflows for automation.
  • Perform and maintain mammalian cell culture to support assay validation and testing workflows.
  • Generate high-quality, reproducible data and maintain detailed experimental records.
  • Help develop reagent QC and assay performance testing methods using qPCR, ddPCR, NGS-based, and other analytical readouts.
  • Help scale workflows for robustness, reproducibility, and eventual automation.
  • Maintain laboratory organization, inventory, and equipment calibration.
  • Contribute to SOP development and documentation as processes mature.


Qualifications

  • Bachelors or Masters degree in Molecular Biology, Biochemistry, Genetics, Bioengineering, or related field.
  • 25 years of relevant industry or advanced academic laboratory experience.
  • Strong hands-on molecular biology skills (PCR, qPCR, enzymatic reactions, NGS library prep).
  • Experience working with complex biological workflows requiring careful technique and documentation.
  • Demonstrated ability to generate reproducible data and troubleshoot experiments.
  • Highly organized with strong attention to detail.
  • Comfortable working in a dynamic startup environment with evolving priorities.


Preferred Qualifications

  • Experience with single-cell genomics workflows (e.g., scRNA-seq, barcoding methods, droplet or bead-based systems).
  • Familiarity with bead handling, surface chemistry, or conjugation methods.
  • Experience with mammalian cell culture and sterile technique.
  • Experience with NGS QC methods (Bioanalyzer, TapeStation, Qubit, fragment analysis).
  • Exposure to automation platforms or high-throughput workflows.
  • Experience using basic statistical tools or data analysis software.


What Success Looks Like in This Role

  • Consistently produces high-quality, reproducible data.
  • Increases experimental throughput and reliability for the assay development team.
  • Proactively identifies workflow improvements.
  • Operates with independence while collaborating effectively.
  • Embodies and reinforces a culture of rigor, efficiency, and accountability.