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Senior Systems Engineer Jobs in Rochester, MN (NOW HIRING)

Sr Mechanical Engineer

Rochester, MN · Hybrid

$87K - $119K/yr

... Senior Mechanical Engineer to lead complex, highperformance building systems across a diverse ... Mastery of mechanical engineering principles and system design * Strong analytical and creative ...

Sr Mechanical Engineer

Rochester, MN · On-site

$87K - $119K/yr

... Senior Mechanical Engineer to lead complex, high-performance building systems across a diverse ... Mastery of mechanical engineering principles and system design * Strong analytical and creative ...

Senior Process Engineer

Stewartville, MN · On-site

$98K - $155K/yr

Description Sr. Process Engineer GEOTEK manufactures engineered composite products for global ... Familiarity with thermoset resin systems (polyester, vinyl-ester, urethane) Physical Work ...

Description GEOTEK/PUPI is seeking a Sr. Applications Engineer to help lead the design and ... Heavy equipment, transportation, building products, or industrial systems * Manufacturing-focused ...

Senior Electrical Project Engineer - Rochester, MN Award-winning Architecture, Engineering ... Prepare engineering opinion of probable cost for electrical systems and review contractor cost ...

Senior Electrical Project Engineer - Rochester, MN Award-winning Architecture, Engineering ... Prepare engineering opinion of probable cost for electrical systems and review contractor cost ...

Our work focuses on sustaining, operating, and improving essential government systems and services ... engineering support for Microsoft 365 GCC, Exchange Online, hybrid Exchange Server, and SharePoint ...

Senior IT Cloud Engineer

Rochester, MN

$56.75 - $75.75/hr

The IT Senior Cloud Engineer ensures that enterprise cloud solutions are optimized for cost and ... Develops internal and external compatibility of the system and subsystems. Develops highly complex ...

New

Manufacturing Sr Engineer I

Rochester, MN

$92K - $126K/yr

What You Can Expect The senior manufacturing engineer is responsible for providing manufacturing ... Experienced with control procedures, such as the Change Management System, Nonconformance Reports ...

New

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Showing results 1-20

Senior Systems Engineer information

See Rochester, MN salary details

$56.9K

$126.8K

$178.9K

How much do senior systems engineer jobs pay per year?

As of Jul 10, 2026, the average yearly pay for senior systems engineer in Rochester, MN is $126,789.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,200.00 and $145,400.00 per year, depending on experience, location, and employer.

What are Senior Systems Engineers?

Senior Systems Engineers are experienced professionals responsible for designing, implementing, and maintaining complex IT systems within an organization. They oversee the integration of hardware and software, ensure system reliability, and troubleshoot advanced technical issues. Senior Systems Engineers often lead projects, mentor junior staff, and collaborate with other departments to meet organizational goals. Their role is critical in maintaining the infrastructure that supports business operations.

What are some common challenges faced by Senior Systems Engineers when integrating new technologies into existing infrastructure?

Senior Systems Engineers often encounter challenges such as ensuring compatibility between legacy systems and new technologies, minimizing downtime during migrations, and addressing unforeseen security vulnerabilities. Effective integration requires thorough planning, cross-team collaboration, and detailed testing to avoid disruptions to business operations. Staying current with emerging technologies and adopting best practices for change management are essential for overcoming these challenges and ensuring smooth implementation.

What are the key skills and qualifications needed to thrive as a Senior Systems Engineer, and why are they important?

To thrive as a Senior Systems Engineer, you need expertise in systems architecture, troubleshooting, and network administration, typically supported by a degree in computer science or a related field and several years of relevant experience. Familiarity with virtualization platforms, cloud services (like AWS or Azure), automation tools (such as Ansible or PowerShell), and certifications like CompTIA, Microsoft, or Cisco are often required. Outstanding problem-solving, communication, and project management skills help you lead initiatives and collaborate effectively across teams. These competencies are crucial for ensuring system reliability, scalability, and security in complex IT environments.

What Is a Senior Systems Engineer?

A senior systems engineer is an IT (information technology) professional tasked with designing and maintaining network systems and security. Examples include large server or storage systems, computer networks, and mainframes. As a systems engineer, your primary duties are to oversee the daily operations of your facility and lead a team of engineers in designing new systems to replace old ones. You may work for a company that provides engineering services and solutions for other businesses, or you may be part of a large university or other institution's IT department. Skills needed for the career include the ability to work independently, leadership, and analytical problem-solving. A bachelor’s degree in electrical engineering or IT and significant experience in a lower systems engineering position are essential qualifications.

What is the difference between Senior Systems Engineer vs Systems Administrator?

AspectSenior Systems EngineerSystems Administrator
CertificationsCompTIA Security+, Cisco CCNA, Microsoft certificationsCompTIA A+, Network+, Microsoft certifications
Work EnvironmentDesigning, implementing, and troubleshooting complex systemsManaging daily system operations and user support
Industry UsageIT, technology, enterprise environmentsIT support, small to medium businesses

While both roles involve working with IT systems, Senior Systems Engineers focus on designing and implementing complex infrastructure, whereas Systems Administrators handle routine maintenance and user support. The senior role typically requires more advanced certifications and experience, and often involves strategic planning and system architecture.

What are the most commonly searched types of Systems Engineer jobs in Rochester, MN? The most popular types of Systems Engineer jobs in Rochester, MN are:
What are popular job titles related to Senior Systems Engineer jobs in Rochester, MN? For Senior Systems Engineer jobs in Rochester, MN, the most frequently searched job titles are:
What cities near Rochester, MN are hiring for Senior Systems Engineer jobs? Cities near Rochester, MN with the most Senior Systems Engineer job openings:
Infographic showing various Senior Systems Engineer job openings in Rochester, MN as of July 2026, with employment types broken down into 92% Full Time, 5% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $126,789 per year, or $61 per hour.
Senior Engineer - Center of Regenerative Biotherapeutics

Senior Engineer - Center of Regenerative Biotherapeutics

Mayo Clinic

Rochester, MN • On-site

$95K - $131K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 4 days ago

New


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 688 frontline employees who took The Breakroom Quiz

105th of 880 rated healthcare providers


Job description


For the Center of Regenerative Biotherapeutics, the Senior Engineer designs and develops components of biomedical-related engineering systems, applying knowledge of complex principles, theories, concepts, tools and techniques to the design challenges -- Essentially we engineer solutions to manufacturing problems in cutting edge science but also problem solve a plethora of issues. Our Senior Engineer:
  • Serves as a Technical Lead for projects
  • Provides technical and work direction to project team members and completes technical work as needed
  • Mentors and coaches other staff as required
  • May lead in evaluating new technologies and capital equipment
  • Understands and complies with relevant portions of Quality Management System
  • Has unit-specific expertise in safety risk management and continues to work to develop expertise in regulatory requirements applicable to his/her unit

Necessary skills: Self-starter who functions effectively in a multi-disciplinary development environment. Demonstrated ability to effectively communicate with team members, physicians and health care providers. Possesses effective oral communication and presentation skills. Develops engineering and technical documentation.
Qualifications
BS in Engineering or a related field (Biomedical Engineering preferred) and 5 years of professional engineering experience; Or MS in Engineering or related field and 3 year of professional engineering experience; Or, PhD in Engineering or related field and 1 year of professional engineering experience.
Masters or PhD preferred, as well as early-to-mid career level candidates.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

What Mayo Clinic employees say

Pay

Benefits

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Workplace

Get the full story on Breakroom


Mayo Clinic logo

About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919