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Senior Software Developer Engineer Jobs in Fort Myers, FL

Sr. Software Engineer, LIMS

Fort Myers, FL · Hybrid

$114K - $150K/yr

NeoGenomics is looking for a Senior Software Engineer (LIMS) who wants to learn to continue to learn in order to allow our company to grow. This is a hybrid position to work out of Ramsey, NJ or Fort ...

Senior Software Engineer - HYBRID

Bonita Springs, FL · On-site +1

$115K - $152K/yr

About ReachMobi An industry-leading mobile app developer, ReachMobi works tirelessly to connect ... NET and modern software development practices. * Hands-on experience with AWS technologies (EC2 ...

Senior Embedded Software Engineer

Fort Myers, FL · On-site

$112K - $146K/yr

As our Senior Embedded Software Engineer, you'll play a pivotal role within our embedded Linux-based software organization for Seakeeper and Seakeeper Ride products. You'll be a major contributor to ...

About Software Engineering Roles at Danaher Are you passionate about building real-world applications, writing clean code, and solving meaningful technical challenges? As a Software Engineering ...

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Senior Software Developer Engineer information

See Fort Myers, FL salary details

$14

$57

$81

How much do senior software developer engineer jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for senior software developer engineer in Fort Myers, FL is $57.62, according to ZipRecruiter salary data. Most workers in this role earn between $48.89 and $64.62 per hour, depending on experience, location, and employer.

What is a senior software developer engineer?

Senior Software Developer Engineers are experienced professionals who design, develop, and maintain complex software systems. They lead technical projects, mentor junior developers, and collaborate with cross-functional teams to deliver high-quality solutions. Their responsibilities often include architecting software, reviewing code, ensuring best practices, and troubleshooting critical issues. Senior developers play a key role in shaping technical strategies and guiding the overall direction of software projects.

What are the key skills and qualifications needed to thrive as a senior software developer engineer?

A Senior Software Developer Engineer requires advanced programming skills, deep understanding of software architecture, and several years of experience with a relevant degree in computer science or a related field. Familiarity with modern development frameworks, version control systems like Git, and certifications such as AWS Certified Developer or Microsoft Certified: Azure Developer Associate are often expected. Strong problem-solving abilities, effective communication, and leadership skills help in mentoring teams and collaborating on complex projects. These competencies ensure high-quality software delivery, efficient teamwork, and innovation within dynamic tech environments.

What are some common challenges faced by senior software developer engineers when leading project teams?

Senior Software Developer Engineers often encounter challenges such as balancing technical leadership with hands-on coding, managing cross-functional communication, and aligning team members with project goals. They may also need to mentor junior developers while ensuring code quality and timely delivery of features. Navigating competing priorities and rapidly changing requirements requires strong problem-solving skills and adaptability, as well as effective collaboration with project managers, designers, and QA teams.

What is the difference between Senior Software Developer Engineer vs Software Developer?

AspectSenior Software Developer EngineerSoftware Developer
Required CredentialsBachelor's degree in CS or related field; 3+ years experience; sometimes certifications like Microsoft or AWSBachelor's degree in CS or related field; 0-2 years experience; certifications are optional
Work EnvironmentTeam lead roles, project planning, mentoringDevelopment tasks, coding, testing
Employer & Industry UsageTech companies, software firms, startupsSame as Senior Software Developer Engineer

The main difference is experience level and responsibilities. Senior Software Developer Engineers typically have more experience, take on leadership roles, and mentor junior developers, while Software Developers focus on coding and implementing features. Both roles are essential in software development teams, but the senior position involves more strategic and supervisory duties.

What cities near Fort Myers, FL are hiring for Senior Software Developer Engineer jobs?

Cities near Fort Myers, FL with the most Senior Software Developer Engineer job openings:

Infographic showing various Senior Software Developer Engineer job openings in Fort Myers, FL as of August 2026, with employment types broken down into 84% Full Time, 13% Part Time, and 3% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $119,844 per year, or $57.6 per hour.

Sr. Software Engineer, LIMS

NeoGenomics

Fort Myers, FL • Hybrid

$114K - $150K/yr

Full-time

Medical, Retirement, PTO

Re-posted 12 days ago


NeoGenomics rating

8.0

Company rating: 8.0 out of 10

Based on 34 frontline employees who took The Breakroom Quiz

47th of 120 rated laboratories


Job description

Are you motivated to participate in a dynamic, multi-tasking environment? Do you want to join a company that invests in its employees? Are you seeking a position where you can use your skills while continuing to be challenged and learn? Then we encourage you to dive deeper into this opportunity.

We believe in career development and empowering our employees. Not only do we provide career coaches internally, but we offer many training opportunities to expand your knowledge base! We have highly competitive benefits with a variety HMO and PPO options. We have company 401k match along with an Employee Stock Purchase Program. We have tuition reimbursement, leadership development, and even start employees off with 16 days of paid time off plus holidays. We offer wellness courses and have highly engaged employee resource groups. Come join the Neo team and be part of our amazing World Class Culture!

NeoGenomics is looking for a Senior Software Engineer (LIMS) who wants to learn to continue to learn in order to allow our company to grow. This is a hybrid position to work out of Ramsey, NJ or Fort Myers, FL.

Now that you know what we're looking for in talent, let us tell you why you'd want to work at NeoGenomics:

As an employer, we promise to provide you with a purpose driven mission in which you have the opportunity to save lives by improving patient care through the exceptional work you perform. Together, we will become the world's leading cancer reference laboratory.

Position Summary: 

As a Senior Software Engineer (LIMS) you are responsible for supporting and advancing in-house Laboratory Information Management System (LIMS) development initiatives. This role designs, develops, reviews, and maintains application solutions while ensuring system performance, reliability, and scalability. Key responsibilities include conducting architecture and code reviews, identifying and resolving complex software defects, performing root cause analysis, and implementing performance optimization strategies. The Senior Software Engineer partners closely with Quality Assurance teams to provide technical oversight, validate code quality, and ensure adherence to development standards and best practices across existing code bases. This is a hybrid position, requiring a minimum of two days per week in the office.

Responsibilities:

  • Design, develop, test, andmaintainscalable, high-performance software applications using C#, .NET Framework, and .NET Core/.NET 8+. 
  • Architect and implement RESTful APIs, microservices, and event-driven solutions to support enterprise business applications. 
  • Collaborate with product managers, architects, QA engineers, and business stakeholders to define technical requirements and deliver high-quality solutions. 
  • Design, configure, andmaintainLIMS workflows, sample lifecycles, tests, and specifications. 
  • Develop and support custom configurations, scripts, rules, and extensions 
  • Configure andoptimizelaboratory processes such as: 
  • Sample logging and tracking 
  • Testing, results entry, review, and approval 
  • Integrate LIMS with laboratory instruments and other lab applications 

Education, Experience & Qualifications:

  • Bachelor’s Degree in Computer Science, Information Technology or a related field 
  • 7+ years of experience in software development ina .NETenvironment. 
  • Healthcare Industryand/orLaboratory Information Management Systems (LIMS) experience required 
  • Experience working within the healthcare, life sciences, or other highly regulated industries.
  • Must be authorized to work in the United States without the need for current or future employer sponsorship.
  • Solidexpertisein C# isrequired; experience with Java and Python frameworks is a plus. 
  • Extensive experience building scalable backend solutionsutilizingASP.NET Framework, RESTful services, andmicroservicesarchitecture. 
  • Proficiencyin Microsoft SQLServer;experience working with a variety of SQL and NoSQL databases is a plus. 
  • Experience with cloud platforms (AWS, Azure) 
  • Solid understanding of data structures, algorithms, and object-oriented design principles, and designing and building data models to improve accessibility, efficiency, and quality of data. 
  • Experience building andmaintainingscalable,highly available, and fault-tolerant systems 
  • Strong hands-on skills with a proven ability to improve application architecture and resolve code-level issues quickly. 
  • Ability to perform Root Cause Analysis on high-impact issues within the application. 
  • Understanding ofIT Security and Compliance audit processes. 

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