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Senior Scientist Protein Engineering Jobs (NOW HIRING)

Merck & Co.

$100K - $136K/yr

D. in Biochemistry, Computational Biology, Protein Engineering, Physics, Bioengineering, Computer ... Science, Molecular Biology, Chemistry, Pharmaceutical Science, or a related STEM field and a ...

MSD

Sr. Scientist, Generative Protein Design

Cambridge, MA · On-site

$100K - $136K/yr

Ph.D. in Biochemistry, Computational Biology, Protein Engineering, Physics, Bioengineering ... Commitment to scientific excellence and rigor. * Excellent communication and collaboration skills.

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Senior Scientist Protein Engineering information

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$66.5K

$110.5K

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How much do senior scientist protein engineering jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior scientist protein engineering in the United States is $110,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,500.00 and $125,000.00 per year, depending on experience, location, and employer.

What are the main collaborative interactions a senior scientist in protein engineering can expect within a typical biotech or pharmaceutical company?

As a Senior Scientist in Protein Engineering, you’ll regularly collaborate with cross-functional teams, including molecular biologists, bioinformaticians, process development scientists, and project managers. These interactions often involve sharing data, co-designing experiments, troubleshooting technical challenges, and aligning project timelines. Effective communication skills are essential, as you'll also present findings to both technical and non-technical stakeholders. This collaborative environment not only drives project success but also provides opportunities for professional growth and learning from other scientific disciplines.

What does a senior scientist in protein engineering do?

A Senior Scientist in Protein Engineering leads research and development projects focused on designing and optimizing proteins for specific functions, such as therapeutic use or industrial applications. They use molecular biology, bioinformatics, and biochemical techniques to modify protein structures, improve their properties, and solve complex biological problems. Senior Scientists often oversee junior researchers, collaborate across departments, and contribute to scientific publications and patent applications. Their expertise helps drive innovation in biotechnology, pharmaceuticals, and related fields.

What is the difference between Senior Scientist Protein Engineering vs Research Scientist Protein Engineering?

AspectSenior Scientist Protein EngineeringResearch Scientist Protein Engineering
Required CredentialsMaster's or PhD in Biochemistry, Molecular Biology, or related field; extensive experienceMaster's or PhD in relevant field; less extensive experience
Work EnvironmentLeading projects, mentoring, cross-functional collaborationConducting experiments, data analysis, supporting projects
Employer & Industry UsagePharmaceutical, biotech, research institutionsAcademic labs, biotech companies, research institutions

Senior Scientist Protein Engineering typically involves leading projects, mentoring team members, and applying extensive expertise, whereas Research Scientist Protein Engineering focuses on executing experiments and supporting research efforts. Both roles require advanced degrees and are common in biotech and pharma industries, but the senior role emphasizes leadership and strategic input.

What are the key skills and qualifications needed to thrive as a senior scientist in protein engineering, and why are they important?

To thrive as a Senior Scientist in Protein Engineering, you need advanced knowledge in molecular biology, biochemistry, and protein design, typically supported by a Ph.D. in a relevant field and significant laboratory experience. Familiarity with techniques such as directed evolution, high-throughput screening, and bioinformatics tools like PyMOL and Rosetta, as well as experience with lab automation systems, is essential. Creative problem-solving, strong leadership, and effective communication are crucial soft skills for leading research teams and collaborating across functions. These skills and qualities are vital for driving innovative protein engineering projects that result in impactful scientific and commercial outcomes.
More about Senior Scientist Protein Engineering jobs
What cities are hiring for Senior Scientist Protein Engineering jobs? Cities with the most Senior Scientist Protein Engineering job openings:
What states have the most Senior Scientist Protein Engineering jobs? States with the most job openings for Senior Scientist Protein Engineering jobs include:
What job categories do people searching Senior Scientist Protein Engineering jobs look for? The top searched job categories for Senior Scientist Protein Engineering jobs are:
Senior Scientist Protein Engineering jobs near you
Infographic showing various Senior Scientist Protein Engineering job openings in the United States as of August 2026, with employment types broken down into 90% Full Time, 5% Part Time, 4% Contract, and 1% Nights. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $110,545 per year, or $53.1 per hour.

Scientist II/Senior Scientist, Protein Science (Menlo Park, CA)

Cedent

Menlo Park, CA • On-site

$107K - $147K/yr

Full-time

Re-posted 18 days ago

Job description

Location: Menlo Park, CA
Job Description
We are seeking a Scientist / Sr. Scientist to join the Protein Science team at our Menlo Park HQ. As a member of the Protein Science Team, you will focus on our antibody production and characterization efforts and be part of a highly collaborative, interdisciplinary drug-development team leveraging the discovery of novel natural products for the next-generation of ADC therapies. You will support engineering/design, expression, purification and characterization of antibodies as well as antibody drug conjugates that deliver new drugs to overcome limitations of current cancer treatments and impact patient outcomes. Your role will be instrumental in delivering high-quality molecules to support in vitro and in vivo studies. You will seek solutions to scale antibody production capacity and streamline throughput and timelines for material generation. We are seeking innovative team members inspired by our mission to work collaboratively in building the next-generation drug company. Candidates should demonstrate scientific curiosity, efficient time management, excellent organizational and communication skills, and a passion for science.
The role is laboratory-based.
Key Responsibilities
  • Drive in-house protein/antibody production, including:
    • Design and construction of expression vectors.
    • Maintain mammalian cell culture systems (HEK293, CHO), perform and optimize transient transfections for protein/antibody production.
    • Perform batch and FPLC based purifications (Affinity, IEX, SEC, and other chromatography-based methods) of monoclonal, bispecific and other engineered antibody formats. Maintain the AKTA systems to ensure endotoxin-free.
  • Develop and optimize purification and analytical characterization methods and protocols for antibodies and antibody drug-conjugates to support in vitro and in vivo studies.
  • Oversee external production efforts by CRO partners.
  • Ensure the highest standard of quality in antibody and antibody drug-conjugate production and batch records.
  • Maintain detailed laboratory notebooks, analyze experimental data and interpret results to guide decision-making processes.
  • Proactively identify workflow limitations and implement solutions.
  • Collaborate with a diverse team to answer scientific questions and deliver quality and timely findings in support of therapeutic candidate advancement.
  • Effectively communicate findings and interpretation of results.
  • Comply with company health and safety policies and general laboratory practices.
Qualifications
  • Scientist II: Bachelor or Master Degree in protein sciences or relevant field with > 15 years hands-on industry experience in protein science is required.
  • Sr. Scientist: PhD in Molecular Biology, Biochemistry, Structural Biology, Immunology, or a related field with > 8 years industry experience in protein science or antibody / protein engineering.
  • Thorough understanding of antibody structure and protein biochemistry best practices.
  • Demonstrated experience with molecular biology techniques, including DNA construct design, PCR, DNA purification and molecular cloning is required.
  • Demonstrated experience with sterile technique and suspension cell culture for protein production is required.
  • Demonstrated expertise with AKTA systems and Unicorn software is required.
  • Significant knowledge and hands-on experience in analytical methods (such as HPLC, aSEC, IEX, HIC, LCMS, SDS-PAGE, ce-SDS, ce-IEF, HCP and endotoxin detection) is required.
  • Experience with gram scale antibody production and purification and/or experience with antibody-drug conjugate (ADC) technologies, including familiarity with linker-payload strategies, conjugation methods, and biophysical and functional evaluation of ADCs is highly desired.
  • Experience with target binding assays, developability assessments and/or CRO management is a plus.
  • Strong desire to continue seeking new technological innovations supporting laboratory work.
  • Excellent analytical and problem-solving skills, with the ability to troubleshoot experiments and propose innovative solutions.
  • Effective communication and collaboration skills, with the ability to work independently and as part of a multidisciplinary research team.
  • Self-motivation, initiative and boldness to dive into a fast-paced new startup.
What We Offer
  • A flexible and dynamic work environment where you pave your own path, Client cultivates employees' unique strengths at all levels and provides mobility across departments.
  • "All Hands Meetings" provide an opportunity to share company and team updates. These meetings are rooted in our value of transparency. They are designed to foster a culture of collaboration, curiosity, and open communication.
  • Rapid career advancement for driven performers.
  • Access to scientific conferences all over the country throughout the year.
  • A range of amenities, courtesy of the Menlo Park Labs business park, including shuttle, gym, rock-climbing wall, pool, sports courts, cafe, bike lockers, and free EV charging stations.
  • Opportunities to engage with the Client community through team-building events like our monthly Client Happy Hour and holiday parties.
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About Cedent

Sourced by ZipRecruiter

CEDENT strives to attract and retain the best people and provide an environment where they can all develop professionally and build a rewarding career. As a result, we create an inclusive environment that is rich in diversity, acknowledges each individual's uniqueness and promotes respect, personal achievement and stewardship. Our clients are global and so is CEDENT. We build and maintain a global workforce that includes people from different backgrounds, with a vast range of skills and experience all united by a common culture and commitment to help our clients achieve high performance. Cultivating a diverse workforce and inclusive work environment makes business sense. Our peoples varied skills are the talent engine that powers CEDENT, enabling it in turn to deliver the innovative solutions that help our clients outperform competitors.

Industry

It services

Company size

11 - 50 Employees

Headquarters location

Plano, TX, US

Year founded

2008

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