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Senior Scientist Downstream Process Development Jobs in Raleigh, NC

Syngenta Group

Senior Scientist I

Durham, NC · On-site

$88K - $120K/yr

To support this mission, Syngenta is seeking a Senior Scientist in Durham, NC. This role will be ... A culture that celebrates belonging and collaboration, promotes professional development and ...

Syngenta

Senior Scientist I

Durham, NC

$88K - $120K/yr

To support this mission, Syngenta is seeking a Senior Scientist in Durham, NC. This role will be ... A culture that celebrates belonging and collaboration, promotes professional development and ...

MedPharm

Scientist III, Analytical R/D

Durham, NC · On-site

Position Summary The Scientist III/ Sr. Scientist is responsible for developing and validating ... • Process Development/ Formulation R&D • Quality Control • Quality Assurance Travel ...

MedPharm

Scientist III, Analytical R/D

Durham, NC · On-site

Position Summary The Scientist III/ Sr. Scientist is responsible for developing and validating ... Process Development/ Formulation R&D · Quality Control · Quality Assurance Travel requirements

Cambrex

Sr. Scientist II (ARD)

Durham, NC · On-site

$86K - $117K/yr

Cambrex is a leading global contract development and manufacturing organization (CDMO) that ... Execute analytical methods for in-process control, release testing and stability monitoring of bulk ...

MSD

Senior Specialist, Process Support Lab

Durham, NC · On-site

... scientists and engineers that are study leads for analytical projects.The candidate must have ... downstream, drug product, analytical) to lead and support late-stage process development, scale ...

Cambrex

Sr. Scientist I (ARD)

Durham, NC · On-site

$86K - $117K/yr

Cambrex is a leading global contract development and manufacturing organization (CDMO) that ... Responsibilities: * Execute analytical methods for in-process control, release testing and ...

Cambrex

Sr. Scientist II (ARD)

Durham, NC · On-site

$86K - $117K/yr

Cambrex is a leading global contract development and manufacturing organization (CDMO) that ... Execute analytical methods for in-process control, release testing and stability monitoring of bulk ...

Fujifilm

Senior Process Engineer 1

Holly Springs, NC

$90K - $116K/yr

Supports development of procurement packages by partnering with Project Engineering * Identifies ... Partners with the Process Engineering/Science teams as a lead for identifying process optimizations ...

New

MSCCN

Sr Engineer I - Holly Springs, NC

Holly Springs, NC · On-site

$100K/yr

... PROCESS DEVELOPMENT (DOWNSTREAM) What you will do Let's do this. Let's change the world. In this ... Master's degree in in Engineering or Science discipline 5+ years of experience in a technical role ...

Cambrex

Sr. Scientist I (ARD)

Durham, NC · On-site

Cambrex is a leading global contract development and manufacturing organization (CDMO) that ... Execute analytical methods for in-process control, release testing and stability monitoring of bulk ...

Fujifilm

Senior Process Engineer 1

Holly Springs, NC · On-site

$90K - $116K/yr

Supports development of procurement packages by partnering with Project Engineering * Identifies ... Partners with the Process Engineering/Science teams as a lead for identifying process optimizations ...

New

Fujifilm

Senior Process Engineer 1

Holly Springs, NC

$90K - $116K/yr

Supports development of procurement packages by partnering with Project Engineering * Identifies ... Partners with the Process Engineering/Science teams as a lead for identifying process optimizations ...

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All JobsScientist Downstream Process Development JobsSenior Scientist Downstream Process Development JobsSenior Scientist Downstream Process Development Jobs in Raleigh, NC

Senior Scientist Downstream Process Development information

See Raleigh, NC salary details

$64.6K

$107.5K

$159.9K

How much do senior scientist downstream process development jobs pay per year?

As of Jul 27, 2026, the average yearly pay for senior scientist downstream process development in Raleigh, NC is $107,458.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,900.00 and $121,500.00 per year, depending on experience, location, and employer.

What does a Senior Scientist in Downstream Process Development do?

A Senior Scientist in Downstream Process Development focuses on developing, optimizing, and scaling up processes to purify biological products such as proteins or antibodies after cell culture (the 'downstream' part of biomanufacturing). They design experiments, analyze data, and work with cross-functional teams to ensure product quality and regulatory compliance. Their role is critical in moving biopharmaceutical products from research to commercial production by ensuring efficient and robust purification processes.

What are the key skills and qualifications needed to thrive as a Senior Scientist in Downstream Process Development, and why are they important?

To thrive as a Senior Scientist in Downstream Process Development, you need advanced knowledge in bioprocess engineering, protein purification, and process scale-up, typically supported by a Ph.D. or Master’s degree in a relevant field. Expertise with chromatography systems (such as AKTA), analytical instrumentation, and familiarity with regulatory requirements like GMP are essential. Strong problem-solving abilities, leadership, and effective communication skills distinguish top performers in this role. These competencies are crucial for developing robust, scalable processes that meet quality standards and drive successful product development.

What are some common challenges faced by Senior Scientists in Downstream Process Development, and how can they be addressed?

Senior Scientists in Downstream Process Development often encounter challenges such as optimizing purification processes for novel biologics, scaling up from lab to production scale, and ensuring product consistency and regulatory compliance. Addressing these challenges typically involves close collaboration with cross-functional teams, continuous process optimization, and staying current with industry advancements in chromatography and filtration technologies. Proactive problem-solving, effective communication, and leveraging data analytics are also key strategies for overcoming obstacles in this role.
What are popular job titles related to Senior Scientist Downstream Process Development jobs in Raleigh, NC? For Senior Scientist Downstream Process Development jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Senior Scientist Downstream Process Development jobs in Raleigh, NC look for? The top searched job categories for Senior Scientist Downstream Process Development jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Senior Scientist Downstream Process Development jobs? Cities near Raleigh, NC with the most Senior Scientist Downstream Process Development job openings:
Senior Scientist Downstream Process Development jobs near you
Infographic showing various Senior Scientist Downstream Process Development job openings in Raleigh, NC as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $107,458 per year, or $51.7 per hour.

Senior Scientist I

Syngenta Group

Durham, NC • On-site

$88K - $120K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 9 days ago

Job description

Company Description
About Syngenta
At Syngenta Seeds Field Crops, we're shaping the future of agriculture and empowering farmers to meet the ever-growing demand for food and fuel. We're a global Ag Tech powerhouse, headquartered in the United States, with passionate, local experts collaborating with farmers to deliver solutions that create market opportunities. We unite precision breeding, advanced biotechnology trait choice, and digital platforms for unmatched in-field performance. Our seeds help mitigate risks such as disease, insect, weed, and extreme weather pressures, all while promoting sustainable farming practices that protect and enhance our planet. Join our mission of revolutionizing food security and transforming agriculture.
Job Description
At Syngenta, our goal is to build the most collaborative and trustworthy team in agriculture, providing top-quality seeds and innovative crop protection solutions that improve farmers' success. To support this mission, Syngenta is seeking a Senior Scientist in Durham, NC. This role will be responsible for establishing multiple plant nematode species: cyst nematode, root-knot nematode, and lesion nematode, using soil and sterile cultures. Lead and support trait discovery and validation projects by conducting hands-on experiments, collaborating with key experts and functions both within and outside of Syngenta.
Accountabilities:
  • Design and implement experiments to evaluate lead performance against Soybean cyst nematode, root-knot nematodes and lesion nematodes.
  • Execute experiments with high quality and precision.
  • Possess deep knowledge and extensive experience through training and work in conducting crop pathology experiments, such as collecting inoculum, culturing inoculum at appropriate scales, inoculation, and disease susceptibility/tolerance/resistance ratings in lab, greenhouse (GH), and field environments.
  • Develop correlations of disease susceptibility/tolerance/resistance ratings in different environments, as required by the project.
  • Create and test hypotheses and make recommendations as a crop pathology expert.
  • Be the focal point of creating, internalizing, and implementing plant pathology techniques and knowledge that enable the organization to meet the needs of growers.
  • Seek out, identify, communicate, and encourage examples of best practice from internal and external sources of information.

Qualifications
  • Ph.D. or equivalent in Plant Nematology, Genetics, Genomics, or a related field, and 4+ years of professional experience working in improving crop resistance against plant-parasitic nematodes.
  • 4+ years of hands-on experience applying general and modern pathology skills in dissecting genetic resistance/tolerance in crops.
  • At least 5+ years of laboratory work experience, such as:
  • Daily work with plant nematodes.
  • Expertise in large-scale nematode production, infection, rating, and reporting.
  • Proficiency in the use of standard software and familiarity with databases.
  • Ability to perform plant studies independently or as part of a team.
  • Strong interest in plant biotechnology and agricultural research.
  • Strong desire to deliver solutions to meet the unmet needs faced by farmers both locally and globally.
  • Ability to solve complex and varied problems based on available data to create working hypotheses, design and execute scientific experiments leading to conclusions, solutions, or new hypotheses.
  • Effective communication skills to convey the appropriate level of detail to the right audience verbally, in writing, or by presentation, and the ability to judge when and who to communicate key information.

Additional Information
What We Offer:
  • A culture that celebrates belonging and collaboration, promotes professional development and strives for a work-life balance that supports the team members. Offers flexible work options to support your work and personal needs.
  • Full Benefit Package (Medical, Dental & Vision) that starts your first day.
  • 401k plan with company match, Profit Sharing & Retirement Savings Contribution.
  • Paid Vacation, Paid Holidays, Maternity and Paternity Leave, Education Assistance, Wellness Programs, Corporate Discounts, among other benefits.

Syngenta has been ranked as a top employer by Science Journal. Learn more about our team and our mission here: https://www.youtube.com/watch?v=OVCN_51GbNI
Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
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