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Senior Rn Jobs in Greenville, SC (NOW HIRING)

Nurse Unit Manager

Greenville, SC · On-site

$37.50 - $49.25/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Nurse Unit Manager RN or LPN REQUIREMENTS: * Graduate from an accredited nursing program * Current ... If you are interested in working for a leader in senior care and share NHC's values of honesty and ...

Nurse Unit Manager

Greenville, SC · On-site

$35 - $46.25/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Nurse Unit Manager RN or LPN REQUIREMENTS: * Graduate from an accredited nursing program * Current ... If you are interested in working for a leader in senior care and share NHC's values of honesty and ...

Showing results 41-60

Senior Rn information

See Greenville, SC salary details

$23.5K

$75.5K

$153.7K

How much do senior rn jobs pay per year?

As of Aug 16, 2026, the average yearly pay for senior rn in Greenville, SC is $75,493.00, according to ZipRecruiter salary data. Most workers in this role earn between $39,000.00 and $96,800.00 per year, depending on experience, location, and employer.

What is the difference between Senior Rn vs Registered Nurse?

AspectSenior RnRegistered Nurse
CredentialsRN license, additional experience, possibly certifications in specialty areasRN license, basic nursing certifications
Work EnvironmentAdvanced clinical settings, leadership roles, specialized unitsHospitals, clinics, long-term care facilities
Employer & Industry UsageHealthcare facilities seeking experienced nursing staff with leadership skillsBroadly used across healthcare settings for general nursing roles
Search & Comparison IntentLooking for experienced nursing roles with leadership or specializationGeneral nursing positions, entry to mid-level roles

The main difference between a Senior Rn and a Registered Nurse is experience level and responsibilities. Senior Rns typically have more clinical experience, may hold specialized certifications, and often take on leadership or mentorship roles within healthcare settings. Registered Nurses are qualified to provide patient care across various environments but may not have the same level of experience or advanced responsibilities as Senior Rns.

What opportunities for leadership and mentorship are available to Senior RNs within a typical healthcare team?

Senior RNs often serve as informal leaders on their units, providing guidance and mentorship to junior nurses, new graduates, and nursing students. They may be tasked with precepting new hires, leading shift huddles, and participating in quality improvement initiatives. Additionally, Senior RNs are frequently involved in interdisciplinary team meetings, contributing their expertise to care planning and patient advocacy. These roles not only enhance the overall quality of care but also offer valuable experience for those considering future advancement into formal leadership or clinical educator positions.

What is a Senior RN?

Senior Registered Nurses (Senior RNs) are experienced nursing professionals who have advanced clinical skills, leadership abilities, and often supervise or mentor other nurses. They typically handle more complex patient care, assist in developing care plans, and may be involved in staff training or management tasks. Senior RNs often serve as a bridge between staff nurses and management, ensuring high standards of patient care and supporting the nursing team.

What skills and qualifications are needed to thrive as a Senior RN?

A Senior RN needs advanced clinical expertise, strong leadership abilities, and a current RN license, often supplemented by a BSN or higher degree and several years of nursing experience. Familiarity with electronic health record (EHR) systems, patient care technologies, and certifications such as ACLS or BLS is typically required. Outstanding communication, mentorship, and critical thinking skills set top performers apart in this role. These competencies are vital for ensuring high-quality patient care, guiding nursing teams, and effectively managing complex healthcare situations.

What are the most commonly searched types of Rn jobs in Greenville, SC?

The most popular types of Rn jobs in Greenville, SC are:

Infographic showing various Senior Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 3% As Needed, 57% Full Time, 16% Part Time, and 24% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $75,493 per year, or $36.3 per hour.

Full-time

Medical

Re-posted 7 days ago


Spartanburg Regional Healthcare System rating

6.7

Company rating: 6.7 out of 10

Based on 117 frontline employees who took The Breakroom Quiz

531st of 887 rated healthcare providers


Job description

Job Requirements

Spartanburg Regional Healthcare System located in Spartanburg, SC is seeking to hire FULL TIME Certified Registered Nurse Anesthetists (CRNA) or Certified Anesthesiologist Assistants (CAA) to join our collegial team of providers. The CRNAs and CAAs are credentialed to work at Spartanburg Medical Center - Church Street (SMC Level 1 Trauma), Spartanburg Medical Center - Mary Black campus (MB), Cherokee Medical Center (CMC), and Pelham Medical Center (PMC). Must be a graduate of an accredited CRNA program or anesthesiologist assistant educational program. Highlights of the opportunity include:


Opportunity Highlights:

  • NO CALL, NIGHTS OR WEEKENDS!
  • Dedicated call team for night and weekend coverage
  • Variety of schedule options and 8 weeks of time off!
  • 4-6 week mentorship/orientation
  • Teaching site for 4 nurse anesthesia programs & 1 AA program provides opportunities to teach and/or mentor SRNAs/SAAs

Generous Recruitment Incentives including:

  • Up to $50,000 in Student Loan Forgiveness
  • $50,000 Sign on Bonus
  • Paid Relocation Assistance

Department/System Highlights:

  • Anesthesia care team is comprised of approximately 34 Anesthesiologists and 100 CAAs/CRNAs covering OR, Endo, Cath Lab, L&D, MRI & IR with anesthesia tech support
  • Diverse Case mix at all campuses
  • 4 Facilities ranging in acuity, from a 25 state of the art OR Level 1 Trauma Center to 5 OR Community Hospital
  • No transplant or burns, some healthy peds and limited NICU cases
  • 19,000+ cases annually at SMC - Church Street Campus (Level 1 Trauma Center)
  • EPIC EMR
  • PSLF Approved Institution

Execptional Benefits Including but not limited to:

  • Health insurance starts from date of hire
  • Paid Malpractice to Include Tail Coverage
  • Paid Parental Leave
  • $3,500 in CME Monies annually

Just an hour from the Blue Ridge Mountains and 3 hours from the ocean, housing is moderately priced, educational options abound, and residents value family and community. Commuting is easy, and your recreational opportunities are endless. Come find out why everyone wants to live here, in the Upstate!

Contact Information:                                                 Alternate Contact:

Kristin Baker, Sr. Physician Recruiter                       Taylor Brady, Physician Recruiter

Spartanburg Regional Healthcare System           Spartanburg Regional Healthcare System

P: (864) 560-31 E: kbaker@srhs.com                      P: (864) 560-6171 E: teubanks@srhs.com


Employment Type: FULL_TIME

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About Spartanburg Regional Healthcare System

Sourced by ZipRecruiter

Spartanburg Regional Healthcare System is a leader in the healthcare industry, located in Spartanburg, SC, US. As a comprehensive health system, it offers services encompassing everything from wellness, prevention, and care coordination to specific medical treatments for a wide range of diseases and health issues. Spartanburg Regional Healthcare System was founded in 1921 and has since developed a reputation for excellence and innovative care, growing to include six hospitals, 100 medical offices, 8,000 associates and more than 900 medical staff.

Industry

Recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Spartanburg, SC, US

Year founded

1921