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Senior Python Startup Jobs in New York (NOW HIRING)

About the Role A growing technology startup is hiring a Senior Full Stack Software Engineer to help ... Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI) * Databases: PostgreSQL ...

Senior Backend Engineer

New York, NY · On-site

$175K - $225K/yr

... startup environment Tech Stack → Python → Java → Go → AWS → Redis → Temporal Candidate Profile → 2+ years of software engineering experience → Strong backend engineering experience ...

Senior Platform Engineer

New York, NY · On-site

$114K - $157K/yr

You have either worked as a Product Security Engineer at a startup or have a deep professional ... Strong proficiency in Python, Go, or Node.js. You view infrastructure through the lens of software ...

Design and maintain high performance APIs using Python and cloud services to handle millions of ... Founder level ownership mindset or early stage startup experience preferred * Ability to work ...

Sr Backend Engineer

Manhattan, NY · On-site

$200K - $250K/yr

Design and maintain high performance APIs using Python and cloud services to handle millions of ... Founder level ownership mindset or early stage startup experience preferred * Ability to work ...

Senior DevOps Engineer

New York, NY · On-site

$220K - $260K/yr

Comfort with scripting/programming (Python, Bash, or similar). * Experience with monitoring ... Previous startup experience. Why Stack AI? * Work at the cutting edge of AI + infrastructure

Senior Data Engineer

New York, NY · On-site +1

$176K - $198K/yr

Testing automation via pytest * uv as our Python package manager * Snowflake as our data warehouse ... Experience in an early startup * Experience with setting up and administrating a Business ...

Senior Software Engineer

Manhattan, NY · On-site

$134K - $177K/yr

As a Senior Software Engineer, you will lead the research, design, implementation, and support of ... a startup or high-growth environment • Highly skilled in Javascript/Typescript and Python • ...

Design and maintain high performance APIs using Python and cloud services to handle millions of ... Founder level ownership mindset or early stage startup experience preferred * Ability to work ...

Design and maintain high performance APIs using Python and cloud services to handle millions of ... Founder level ownership mindset or early stage startup experience preferred * Ability to work ...

Senior Software Engineer

Manhattan, NY · On-site

$134K - $177K/yr

... Python, FastAPI, Node.js), relational databases (Postgres/MySQL), and optionally frontend ... or startup early hire, with history building production products from scratch • Bonus if you're ...

Senior Software Engineer

New York, NY · On-site +1

$134K - $176K/yr

We are seeking a Senior Software Engineer to join our founding team. As one of our first ... Bring full-stack experience (e.g., React/TypeScript, Node.js, Python, or similar). * Have startup ...

Clerq - Senior Software Engineer

New York, NY · On-site

$134K - $176K/yr

We are looking for a Senior Software Engineer to join our early engineering team. The ideal ... with Python/Django strongly preferred) * Previous (early stage) startup experience is a plus

Senior Software Engineer

New York, NY · On-site

$200K - $275K/yr

You'll work end-to-end across a Python/FastAPI backend, a Next.js/TypeScript dashboard, and the ... a startup, high-velocity SaaS, or AI-driven company - Production LLM experience - you've shipped ...

PostgreSQL, Python, SQL * AWS (S3, Lambda, ECS Fargate, Glue, Athena, Step Functions) * Parquet ... Ground-floor opportunity at a fast-scaling startup * Chart your own growth path as we expand * Full ...

Showing results 21-40

Senior Python Startup information

What is the difference between Senior Python Startup vs Python Developer?

AspectSenior Python StartupPython Developer
CredentialsBachelor's or higher in CS, experience in startupsBachelor's in CS or related field, some experience
Work EnvironmentFast-paced startup, cross-functional teamsEstablished companies or startups, team-based
Industry UsageTech startups, innovative projectsVaried industries, software development
Search IntentSenior roles, startup environment, advanced skillsEntry to mid-level roles, Python programming

Senior Python Startup roles typically require more experience, leadership skills, and familiarity with startup environments. Python Developers may have similar technical skills but often at an earlier career stage and in more established settings. The main difference lies in experience level and work context, with Senior Python Startup positions emphasizing leadership and startup agility.

What are the most commonly searched types of Python Startup jobs in New York?

The most popular types of Python Startup jobs in New York are:

What cities in New York are hiring for Senior Python Startup jobs?

Cities in New York with the most Senior Python Startup job openings:

Infographic showing various Senior Python Startup job openings in New York as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 9% Part Time, and 5% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution.

Senior Full Stack Software Engineer

twenty80.io

New York, NY • On-site, Remote

$160K - $210K/yr

Full-time

Medical, Dental, Vision, PTO

Re-posted 22 days ago


Job description

About the Role

A growing technology startup is hiring a Senior Full Stack Software Engineer to help build and scale its core product. This engineer will work across the frontend and backend, contributing directly to customer-facing features as well as internal systems. The role offers a high level of ownership and influence over technical decisions in a fast-paced environment.

This position is well-suited for an engineer who enjoys working closely with product and design, shipping quickly, and improving systems over time.

What You’ll Do
  • Build and maintain full stack web applications used by customers and internal teams

  • Develop scalable backend services and APIs to support product features

  • Implement modern, responsive frontend interfaces with a focus on usability and performance

  • Collaborate with product managers and designers to define requirements and deliver solutions

  • Contribute to architectural decisions and technical roadmap planning

  • Write high-quality, well-tested code and participate in code reviews

  • Help improve engineering processes, tooling, and system reliability

  • Mentor junior engineers and contribute to a strong engineering culture

Tech Environment

The engineering team works with a modern startup stack, including:

  • Frontend: React, TypeScript, Next.js

  • Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI)

  • Databases: PostgreSQL, Redis

  • Cloud & Infrastructure: AWS or GCP, Docker, CI/CD

  • APIs: REST and GraphQL

  • Tools: Git, GitHub, modern monitoring and logging tools

What We’re Looking For
  • 5+ years of professional software engineering experience

  • Strong full stack experience with modern JavaScript/TypeScript

  • Proven experience building and maintaining backend services and APIs

  • Solid understanding of relational databases and data modeling

  • Experience deploying and operating applications in cloud environments

  • Ability to work independently and take ownership of projects

  • Prior experience in a startup or fast-moving product team is a plus

Compensation & Benefits
  • Base Salary: $160,000 – $210,000 (San Francisco senior-level range)

  • Equity: Competitive equity package

  • Benefits: Medical, dental, vision coverage; flexible PTO; standard startup benefits

  • Work Model: Hybrid or remote-friendly depending on location and team needs

Equal Opportunity

This role is with an equal opportunity employer. Qualified applicants will be considered without regard to race, color, religion, gender, sexual orientation, gender identity, age, disability, or veteran status.