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Senior Python Startup Jobs in California (NOW HIRING)

Full-time · On-site at either our SF or LA offices Tech Stack Python, C++, PostgreSQL, Linux ... Prior startup experience or end-to-end product ownership Key Responsibilities * Improve the backend ...

We're a post-Series A startup backed by world-class investors, already profitable, and growing fast ... Design, develop, and deploy backend services using Python and AWS infrastructure * Contribute to ...

We're a post-Series A startup backed by world-class investors, already profitable, and growing fast ... Design, develop, and deploy backend services using Python and AWS infrastructure * Contribute to ...

Full-time • On-site at either our SF or LA offices Tech Stack Python, C++, PostgreSQL, Linux ... Prior startup experience or end-to-end product ownership Key Responsibilities * Improve the backend ...

Full-time • On-site at either our SF or LA offices Tech Stack Python, C++, PostgreSQL, Linux ... Prior startup experience or end-to-end product ownership Key Responsibilities * Improve the backend ...

Senior AI Engineer

San Jose, CA · Hybrid

$187K - $215K/yr

Write clear, well-structured Python and TypeScript code for production ML systems What We Are ... Former founder or early employee at a startup Why This Role * Define the core AI systems of the ...

Senior Software Engineer

San Francisco, CA · On-site

$144K - $190K/yr

Strong proficiency in Python, Node.js, or Go, with experience in cloud-based architectures (AWS ... Startup mindset - comfortable with ambiguity, eager to take ownership, and ship quickly. * Bonus:

Senior Product Engineer

San Francisco, CA · On-site

$175K - $200K/yr

One team, one dream About this role We are looking for a Senior Full Stack Engineer who loves ... Startup experience (not required, but we build and move fast!) Our tech stack * Backend * Python ...

Senior Product Engineer

San Francisco, CA · On-site +1

$175K - $200K/yr

... looking for a Senior Full Stack Engineer who loves building application code and scalable ... Startup experience (not required, but we build and move fast!) Our tech stack Backend Python ...

Senior Data Analyst

San Francisco, CA · On-site

$101K - $127K/yr

About the job Senior Data Analyst Senior Data Analyst Location: San Francisco (On-site) Employment ... analytics (startup experience preferred) * Strong SQL and Python skills for data analysis

One team, one dream About this role We are looking for a Senior Full Stack Engineer who loves ... Startup experience (not required, but we build and move fast!) Our tech stack * Backend * Python ...

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Senior Python Startup information

What is the difference between Senior Python Startup vs Python Developer?

AspectSenior Python StartupPython Developer
CredentialsBachelor's or higher in CS, experience in startupsBachelor's in CS or related field, some experience
Work EnvironmentFast-paced startup, cross-functional teamsEstablished companies or startups, team-based
Industry UsageTech startups, innovative projectsVaried industries, software development
Search IntentSenior roles, startup environment, advanced skillsEntry to mid-level roles, Python programming

Senior Python Startup roles typically require more experience, leadership skills, and familiarity with startup environments. Python Developers may have similar technical skills but often at an earlier career stage and in more established settings. The main difference lies in experience level and work context, with Senior Python Startup positions emphasizing leadership and startup agility.

What are the most commonly searched types of Python Startup jobs in California? The most popular types of Python Startup jobs in California are:
What job categories do people searching Senior Python Startup jobs in California look for? The top searched job categories for Senior Python Startup jobs in California are:
What cities in California are hiring for Senior Python Startup jobs? Cities in California with the most Senior Python Startup job openings:

Senior Infrastructure Engineer

Vast.ai

San Francisco, CA • On-site

$180K - $300K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 19 days ago


Job description

Staff Infrastructure EngineerAbout Us

Vast.ai's cloud powers AI projects and businesses all over the world. We are democratizing and decentralizing AI computing—reshaping our future for the benefit of humanity.

We are a growing and highly motivated team dedicated to an ambitious technical plan. Our structure is flat, our ambitions are bold, and leadership is earned by shipping excellence.

We seek engineers with strong intrinsic drive, a true passion for advancing the state of the art, and a mix of architecture, coding, and communication skills.

LOCATION: On-site at our office in San Francisco or Westwood, Los Angeles.

About the Role

As a Senior Infrastructure Engineer, you will help design and scale the core systems that power Vast.ai's global GPU marketplace.

You'll work closely with our founders and core engineering team to extend the underlying compute infrastructure — from GPU provisioning and scheduling to billing, orchestration, and marketplace dynamics.

We're looking for someone who has previously built large-scale infrastructure platforms — systems with similarities to Vast.ai, or distributed compute orchestration frameworks.

Full-time · On-site at either our SF or LA offices

Tech Stack

Python, C++, PostgreSQL, Linux, Docker, KVM, Redis, Terraform, AWS, REST/gRPC APIs

Ideal Experience
  • Distributed Systems: Experience building high-throughput backend systems or compute clouds
  • Compute Orchestration: Familiarity with Docker, or custom scheduling frameworks
  • GPU Infrastructure: Understanding of GPU provisioning, driver management, and workload scheduling
  • Billing & Metering: Implemented or integrated usage-based billing and account credit systems
  • Marketplace Dynamics: Knowledge of dynamic pricing, spot instances, or supply-demand balancing mechanisms
  • Security & Multi-Tenancy: Experience designing secure, multi-tenant systems in cloud environments
  • Programming: Strong programming skills in Python and C++; ability to write performant, maintainable, well-architected code
  • Database Expertise: Comfortable designing schemas and queries for large-scale data systems (PostgreSQL preferred)

Bonus points for:

  • Experience with GPU security, virtualization, or zero-trust compute isolation
  • Prior startup experience or end-to-end product ownership
Key Responsibilities
  • Improve the backend systems that power Vast.ai's compute marketplace
  • Integrate GPU provider onboarding, usage tracking, billing, and orchestration APIs
  • Develop scalable infrastructure for workload scheduling and resource management
  • Optimize pricing and marketplace logic for efficiency and transparency
  • Benchmark, profile, and harden systems for performance, reliability, and fault tolerance
  • Collaborate with product and infrastructure teams to shape the future of decentralized compute
Interview Process (≈ 1 week)

After submitting your application, our technical team reviews your credentials. If selected, you'll proceed through the following stages:

  • 15 min – Initial screening with member of your future team (virtual)
  • 40 min – Systems and architectures (virtual)
  • 1 hour – LLM-assisted coding assessment (virtual)
  • 2 hours – Meet and greet with coding assessment (on-site)
Annual Salary Range

$180,000 – $300,000 + equity + benefits

Vast.ai is hiring senior, staff and principal experience levels with compensation commensurate with background, experience, and potential.

Benefits
  • Comprehensive health, dental, vision, and life insurance
  • 401(k) with company match
  • Meaningful early-stage equity
  • Onsite meals, snacks, and close collaboration with founders and tech leads
  • Ambitious, fast-paced startup culture where initiative is rewarded