1

Senior Python Startup Jobs in California (NOW HIRING)

Senior ML Engineer

San Francisco, CA · Remote

$180K - $240K/yr

Career Renew is recruiting for one of its clients a Senior Machine Learning Engineer - this is a ... You're an applied AI engineer who thrives in startup environments, writes clean Python, and can ...

Senior AI Engineer

Cupertino, CA · On-site

$58 - $68/hr

Strong TypeScript development experience ( Python a plus) * Experience building AI-powered ... Startup or highly autonomous engineering experience preferred Education & Experience * Bachelor ...

About the Company We are a stealth-mode battery startup developing cutting-edge battery technology ... Exposure to scripting languages (PowerShell, Bash, Python, etc.) and automation * Familiarity with ...

Senior Data & AI Engineer

San Francisco, CA · On-site

$124K - $169K/yr

Expert in Python * Skilled in data engineering, including SQL architecture, ETL, and data ... Over three years in a high-growth startup with strong engineering culture, mentorship, and code ...

New

Sr. Product Manager

San Francisco, CA

$149K - $196K/yr

Launched in 2012, Koding, a fast-growing startup (with over a million users), is seeking a Senior ... Python...the list goes on! You can experiment with installing/configuring/hacking Wordpress ...

Senior AI/ML Engineer

San Francisco, CA · On-site

$123K - $169K/yr

About the role Our client is a well-funded AI startup building production-grade ML infrastructure ... Strong Python and PyTorch (or JAX) fundamentals * Experience with distributed training, GPU ...

Senior AI/ML Engineer

San Francisco, CA · On-site

$123K - $169K/yr

About the role Our client is a well-funded AI startup building production-grade ML infrastructure ... Strong Python and PyTorch (or JAX) fundamentals * Experience with distributed training, GPU ...

We're a post-Series A startup backed by world-class investors, already profitable, and growing fast ... Design, develop, and deploy backend services using Python and AWS infrastructure * Contribute to ...

We're a post-Series A startup backed by world-class investors, already profitable, and growing fast ... Design, develop, and deploy backend services using Python and AWS infrastructure * Contribute to ...

Be Seen First

... startup that's building the infrastructure behind some of the world's most advanced artificial ... Proficiency in Python and/or JavaScript (Node.js/Next.js) . * Experience with cloud platforms such ...

New

next page

Showing results 1-20

Senior Python Startup information

What is the difference between Senior Python Startup vs Python Developer?

AspectSenior Python StartupPython Developer
CredentialsBachelor's or higher in CS, experience in startupsBachelor's in CS or related field, some experience
Work EnvironmentFast-paced startup, cross-functional teamsEstablished companies or startups, team-based
Industry UsageTech startups, innovative projectsVaried industries, software development
Search IntentSenior roles, startup environment, advanced skillsEntry to mid-level roles, Python programming

Senior Python Startup roles typically require more experience, leadership skills, and familiarity with startup environments. Python Developers may have similar technical skills but often at an earlier career stage and in more established settings. The main difference lies in experience level and work context, with Senior Python Startup positions emphasizing leadership and startup agility.

What are the most commonly searched types of Python Startup jobs in California? The most popular types of Python Startup jobs in California are:
What cities in California are hiring for Senior Python Startup jobs? Cities in California with the most Senior Python Startup job openings:
Infographic showing various Senior Python Startup job openings in California as of July 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 81% Physical, 6% Hybrid, and 13% Remote job distribution.

Senior ML Engineer

Career Renew

San Francisco, CA • Remote

$180K - $240K/yr

Full-time

Medical, PTO

Posted 20 days ago


Job description

Career Renew is recruiting for one of its clients a Senior Machine Learning Engineer - this is a fully remote role for US/Canada based candidates. Salary range: 180-240K USD plus benefits plus equity.
Since 2017, we’ve been on a mission to use AI to resolve as many conversations as possible while elevating human agents to do what they are uniquely good at.

We are looking for a Senior Machine Learning Engineer with 5+ years of experience to join our small but mighty ML team building production-grade AI voice agents used by enterprise customers like AAA and Fanatics. You're an applied AI engineer who thrives in startup environments, writes clean Python, and can ship LLM-powered systems that handle real, high-stakes conversations at scale — not just run experiments.


What will you be doing?

  • Leading the exploration and application of Large Language Models and Generative AI, venturing into new areas within these fields

  • Translating the latest research into high-performing systems and models that can be practically applied to enhance user experiences

  • Help set the team's strategic direction, cultivating an environment that encourages innovation and professional growth

  • Actively engaging in all aspects of development, from ideation and experimentation to implementation and deployment

  • Collaborating with various teams and product managers to develop and implement ML based solutions, ensuring performance optimization and alignment with broader business goals

Requirements:
5 - 10 years of experience in applied ML engineering, building production systems in Python with LLMs or NLP (Mandatory)
Experience building production systems in Python (Mandatory)
Familiarity with low-latency production ML systems (Mandatory)
Experience working at a high-growth startup (Mandatory)
Background in NLU, NLP, or conversational AI (Nice-to-have)
BS/MS/PhD in CS, ML, Mathematics, or closely related field with ML coursework (Mandatory)
Why you should join
  • Industry leader in Voice AI for customer service since 2017 — powering enterprise customers like AAA and Fanatics where 50%+ of callers get fully resolved by the bot with higher satisfaction scores than human agents.
  • $113M raised from top-tier investors including Stripes, Salesforce Ventures and Norwest — Series B closed in 2022 at $78M with strong backing from day one.
  • Work on genuinely cutting-edge AI problems — low latency inference, hallucination reduction, prompt injection guardrails and dynamic conversation design at the frontier of what's possible with LLMs today.
  • Small team means real ownership and real impact — every improvement you ship moves the needle for enterprise customers in high-stakes scenarios (think: someone stranded on the road calling AAA).
  • Remote-first with strong perks — flexible vacation, paid sabbatical after 5 years, comprehensive health benefits, wellness stipend and a tech/learning stipend for conferences, books and courses. Competitive salary ($180K–$230K) plus meaningful equity.