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Senior Python Startup Jobs in Santa Monica, CA (NOW HIRING)

Senior Infrastructure Engineer

Los Angeles, CA ยท On-site

$180K - $300K/yr

Full-time โ€ข On-site at either our SF or LA offices Tech Stack Python, C++, PostgreSQL, Linux ... Prior startup experience or end-to-end product ownership Key Responsibilities * Improve the backend ...

Senior Financial Analyst

Los Angeles, CA ยท Hybrid

$120K - $150K/yr

Familiarity with SQL, Python, LLM APIs, or other automation technologies (preferred). * Experience ... Experience in crypto, fintech, or a high-growth startup environment (preferred). * CFA, MBA, or ...

Senior Staff Engineer

El Segundo, CA ยท On-site

$120 - $160/hr

Languages: Kotlin, Rust, TypeScript, and Python * Deployments: GitHub Actions, Terraform ... Previous experience in a startup or high-growth environment (50-200 employees) * Experience with ...

Senior Staff Engineer

El Segundo, CA ยท On-site

$200K - $235K/yr

Languages: Kotlin, Rust, TypeScript, and Python * Deployments: GitHub Actions, Terraform ... Previous experience in a startup or high-growth environment (50-200 employees) * Experience with ...

Senior Compiler Engineer

Los Angeles, CA ยท On-site

$135K - $210K/yr

... startup mindset to deliver real impact through software innovation. Our work is underpinned by ... Maintain and evolve our bespoke Python DSL used by researchers to construct pulse-level quantum ...

... startup building the operational infrastructure for both non-autonomous and future autonomous ... Proficiency in Microsoft Office required, bonus points for SQL, Python, and/or R proficiency

Role Overview The Sr. Combustion Engineer helps pioneer our rocket-inspired, high-pressure ... automation (Python, MATLAB, etc.) * Background in startup environments or agile hardware ...

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Showing results 1-20

Senior Python Startup information

See Santa Monica, CA salary details

$61.7K

$159.4K

$218.9K

How much do senior python startup jobs pay per year?

As of Sep 5, 2026, the average yearly pay for senior python startup in Santa Monica, CA is $159,369.00, according to ZipRecruiter salary data. Most workers in this role earn between $136,400.00 and $183,500.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Startup vs Python Developer?

AspectSenior Python StartupPython Developer
CredentialsBachelor's or higher in CS, experience in startupsBachelor's in CS or related field, some experience
Work EnvironmentFast-paced startup, cross-functional teamsEstablished companies or startups, team-based
Industry UsageTech startups, innovative projectsVaried industries, software development
Search IntentSenior roles, startup environment, advanced skillsEntry to mid-level roles, Python programming

Senior Python Startup roles typically require more experience, leadership skills, and familiarity with startup environments. Python Developers may have similar technical skills but often at an earlier career stage and in more established settings. The main difference lies in experience level and work context, with Senior Python Startup positions emphasizing leadership and startup agility.

What cities near Santa Monica, CA are hiring for Senior Python Startup jobs?

Cities near Santa Monica, CA with the most Senior Python Startup job openings:

Infographic showing various Senior Python Startup job openings in Santa Monica, CA as of August 2026, with employment types broken down into 1% Internship, 87% Full Time, 4% Part Time, and 8% Contract. Highlights an 81% Physical, 5% Hybrid, and 14% Remote job distribution, with an average salary of $159,369 per year, or $76.6 per hour.

Senior Full Stack Software Engineer

twenty80.io

Los Angeles, CA โ€ข On-site, Remote

$160K - $210K/yr

Full-time

Medical, Dental, Vision, PTO

Re-posted 23 days ago


Job description

About the Role

A growing technology startup is hiring a Senior Full Stack Software Engineer to help build and scale its core product. This engineer will work across the frontend and backend, contributing directly to customer-facing features as well as internal systems. The role offers a high level of ownership and influence over technical decisions in a fast-paced environment.

This position is well-suited for an engineer who enjoys working closely with product and design, shipping quickly, and improving systems over time.

What You’ll Do
  • Build and maintain full stack web applications used by customers and internal teams

  • Develop scalable backend services and APIs to support product features

  • Implement modern, responsive frontend interfaces with a focus on usability and performance

  • Collaborate with product managers and designers to define requirements and deliver solutions

  • Contribute to architectural decisions and technical roadmap planning

  • Write high-quality, well-tested code and participate in code reviews

  • Help improve engineering processes, tooling, and system reliability

  • Mentor junior engineers and contribute to a strong engineering culture

Tech Environment

The engineering team works with a modern startup stack, including:

  • Frontend: React, TypeScript, Next.js

  • Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI)

  • Databases: PostgreSQL, Redis

  • Cloud & Infrastructure: AWS or GCP, Docker, CI/CD

  • APIs: REST and GraphQL

  • Tools: Git, GitHub, modern monitoring and logging tools

What We’re Looking For
  • 5+ years of professional software engineering experience

  • Strong full stack experience with modern JavaScript/TypeScript

  • Proven experience building and maintaining backend services and APIs

  • Solid understanding of relational databases and data modeling

  • Experience deploying and operating applications in cloud environments

  • Ability to work independently and take ownership of projects

  • Prior experience in a startup or fast-moving product team is a plus

Compensation & Benefits
  • Base Salary: $160,000 – $210,000 (San Francisco senior-level range)

  • Equity: Competitive equity package

  • Benefits: Medical, dental, vision coverage; flexible PTO; standard startup benefits

  • Work Model: Hybrid or remote-friendly depending on location and team needs

Equal Opportunity

This role is with an equal opportunity employer. Qualified applicants will be considered without regard to race, color, religion, gender, sexual orientation, gender identity, age, disability, or veteran status.