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Senior Python Software Engineer Jobs in Rochester, NY

Senior Software Engineer

Rochester, NY · On-site

$120K - $159K/yr

Join our mission as a Senior Software Engineer on our R&D Instrument Platforms organization to ... Familiarity with scripting languages such as Python and Bash for automation and tooling.

Senior Specialist, Embedded Software Engineer Job Code: 39159 Job Location: Rochester, NY Job ... Experience in embedded software development using C/C++ and scripting languages such as Python for ...

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

As a key member of our Engineering team, you will be responsible for designing and developing ... Python. * The person in this position needs to occasionally move about inside the office to access ...

Senior Software Engineer

Rochester, NY

$121K - $159K/yr

As a key member of our Engineering team, you will be responsible for designing and developing ... Python. * The person in this position needs to occasionally move about inside the office to access ...

Senior Software Engineer

Rochester, NY · On-site

$80K - $135K/yr

As a key member of our Engineering team, you will be responsible for designing and developing ... Python. * The person in this position needs to occasionally move about inside the office to access ...

SENIOR EMBEDDED SOFTWARE ENGINEER Department: Product Design Services FLSA Status: Exempt Reports to: Operations Manager Pay Range: $93,000 - $125,000 annually Location: Rochester, NY The Role: D3 ...

Senior Software Engineer

Rochester, NY · On-site

$120K - $159K/yr

Welcoming and inclusive culture WeTheHobby is looking for a skilled and solution-driven Senior Software Engineer to design, develop, and maintain the server-side logic, database architecture, and ...

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Senior Python Software Engineer information

See Rochester, NY salary details

$54.3K

$140.1K

$192.4K

How much do senior python software engineer jobs pay per year?

As of Jul 9, 2026, the average yearly pay for senior python software engineer in Rochester, NY is $140,083.00, according to ZipRecruiter salary data. Most workers in this role earn between $119,900.00 and $161,300.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in Rochester, NY? For Senior Python Software Engineer jobs in Rochester, NY, the most frequently searched job titles are:
What cities near Rochester, NY are hiring for Senior Python Software Engineer jobs? Cities near Rochester, NY with the most Senior Python Software Engineer job openings:
Senior Software Engineer

$120K - $159K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 20 days ago


Job description

The Opportunity

QuidelOrtho unites the strengths of Quidel Corporation and Ortho Clinical Diagnostics, creating a world-leading in vitro diagnostics company with award-winning expertise in immunoassay and molecular testing, clinical chemistry and transfusion medicine. We are more than 6,000 strong and do business in over 130 countries, providing answers with fast, accurate and consistent testing where and when they are needed most - home to hospital, lab to clinic.

Our culture puts our team members first and prioritizes actions that support happiness, inspiration and engagement. We strive to build meaningful connections with each other as we believe that employee happiness and business success are linked. Join us in our mission to transform the power of diagnostics into a healthier future for all.

The Position

At QuidelOrtho, we're advancing the power of diagnostics for a healthier future for all. Join our mission as a Senior Software Engineer on our R&D Instrument Platforms organization to support software development with a strong emphasis on building, configuring, and maintaining Unix-like operating systems. This role is ideal for an engineer who can work hands-on with system-level software and build tooling while delivering reliable, testable code in a structured engineering process. This position is responsible for developing software and supporting software development processes and tools. This includes, but is not limited to, requirements development, design, build, implementation, and testing.

This role is based at our beautiful waterfront campus with walking trail, fitness center, and full-service onsite cafeteria in the Rochester, NY region.

NOTE: Relocation assistance is available for candidates relocating from outside of the Rochester area.

The Responsibilities

  • Build, configure, and maintain OS images and platform software for Linux/Unix-like environments.
  • Develop and maintain C++ components that interact with low-level services and system interfaces.
  • Create and execute unit and integration tests; improve automated test coverage over time.
  • Translate system and software requirements into implementation tasks and verification criteria.
  • Produce and review software design documentation (interfaces, module behavior, constraints).
  • Troubleshoot platform, build, and runtime issues across development and integration environments.
  • Perform other work-related duties as assigned.

The Individual

      Required Skills:

      • B.S. or M.S. Degree in Computer Science, Computer Engineering or a related discipline required
      • Minimum of 5 years required with bachelor's or 3 years with master's degree, preferably in a medical device environment or equivalent combination of education and experience.
      • Experience with cross-compilation, build systems (e.g., CMake/Make), and shell tooling.
      • Experience writing unit tests and integrating tests into CI pipelines.
      • Strong debugging and root-cause analysis skills.

      Preferred Skills:

      • Embedded systems development, including RTOS and real-time applications.
      • Familiarity with scripting languages such as Python and Bash for automation and tooling.
      • Proficiency in modern cross-platform software design using contemporary build systems (e.g., CMake, etc.).
      • Familiarity with USB, Ethernet, and CAN communication protocols.
      • Direct experience with QNX BSPs, startup/configuration, and deployment workflows.
      • Familiarity with embedded or real-time systems constraints.
      • Experience with static analysis and secure coding practices.

      The Key Stake Holders

      Internal Customers:

      • Systems Engineers, Hardware Engineers, Quality/Regulatory, Operations, Marketing, Manufacturing, Service, Clinical Medical Affairs, Project Management Office

      External Customers:

      • Software Development partners and suppliers.

        How We Work

        At QuidelOrtho, our culture is shaped by four core behaviors that guide how we collaborate, make decisions, and support each other and those we serve. The ideal candidate will exhibit these behaviors, as we believe they're essential to how we thrive as a team and achieve meaningful impact:

        • Thrive Together - Collaborate intentionally, grow as a team
        • Make It Happen - Focus on priorities, embrace continuous improvement
        • Commit to Service - Cultivate a service mindset
        • Embrace Inclusion - Be open and authentic, welcome diverse perspectives

        The Work Environment

        No strenuous physical activity, though occasional light lifting of files and related materials is required. 30% of time in meetings, working with team, or talking on the phone, 70% of the time at the desk on computer, doing analytical work.

        The Physical Demands

        Most of the work is to be performed in an office-type open space environment using laptop computers and accessories (sitting or standing). Occasional lifting/carrying of computers and accessories or similar items.

        Salary Transparency

        The salary range for this position takes into account a wide range of factors including education, experience, knowledge, skills, geography, and abilities of the candidate, in addition to internal equity and alignment with market data. At QuidelOrtho, it is not typical for an individual to be hired at or near the top range for their role and compensation decisions are dependent on the facts and circumstances of each case. The salary range for this position is $100,000 to $120,000 and is bonus eligible. QuidelOrtho offers a comprehensive benefits package including medical, dental, vision, life, and disability insurance, along with a 401(k) plan, employee assistance program, Employee Stock Purchase Plan, paid time off (including sick time), and paid Holidays. All benefits are non-contractual, and QuidelOrtho may amend, terminate, or enhance the benefits provided, as it deems appropriate.

        Equal Opportunity

        QuidelOrtho believes in Equal Opportunity for all and is committed to ensuring all individuals, including individuals with disabilities, have an opportunity to apply for those positions that they are interested in and qualify for without regard to race, religion, color, national origin, citizenship, sex, sexual orientation, gender identity, age, veteran status, disability, genetic information, or any other protected characteristic. QuidelOrtho is also committed to providing reasonable accommodations to qualified individuals so that an individual can perform their duties. If you are interested in applying for an employment opportunity and require special assistance or an accommodation to apply due to a disability, please contact us at recruiting@quidelortho.com.