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Senior Python Software Engineer Jobs in Greenville, SC

TRULEO

Senior Software Engineer

Greenville, SC · On-site

$115K - $151K/yr

... a Senior Software Engineer to join their engineering team. In this full-stack role, you will work ... with Python, machine learning (ML), ML Ops • Experience building AI-powered systems. • ...

Truleo

Senior Software Engineer

Greenville, SC · On-site

$115K - $151K/yr

The Role We're hiring a Senior Software Engineer to join our engineering team in Greenville, SC, on ... Experience with Python, machine learning (ML), ML Ops * Experience building AI-powered systems.

Truleo

Senior Software Engineer

Greenville, SC · On-site

$115K - $151K/yr

The Role We're hiring a Senior Software Engineer to join our engineering team in Greenville, SC, on ... Experience with Python, machine learning (ML), ML Ops * Experience building AI-powered systems.

TRULEO

Senior Software Engineer

Greenville, SC · On-site

$115K - $151K/yr

The Role We're hiring a Senior Software Engineer to join our engineering team in Greenville, SC, on ... Experience with Python, machine learning (ML), ML Ops * Experience building AI-powered systems.

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Embedded Software Engineer - Job Title: Software Engineer Department: Engineering Reports To ... Working knowledge of higher-level programming languages, including C++ and Python. * Experience in ...

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Embedded Software Engineer - Job Title: Software Engineer Department: Engineering Reports To ... Working knowledge of higher-level programming languages, including C++ and Python. * Experience in ...

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Embedded Software Engineer - Job Title: Software Engineer Department: Engineering Reports To ... Working knowledge of higher-level programming languages, including C++ and Python. * Experience in ...

Michelin

Senior Software Engineer

Pendleton, SC

$102K - $135K/yr

Senior Software Engineer Build a Career That Matters with One of the World's Most Respected Employers! - - - - - - - - - - - - Michelin is hiring! We are looking for a software development ...

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Working knowledge of C++ and Python. QUALIFICATIONS * Bachelor's Degree in Computer Engineering, Software Engineering, or related field. * Minimum 5 years of relevant experience. * US Person required ...

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Working knowledge of C++ and Python. QUALIFICATIONS * Bachelor's Degree in Computer Engineering, Software Engineering, or related field. * Minimum 5 years of relevant experience. * US Person required ...

AERONIX INC

Embedded Software Engineer

Greenville, SC · On-site

$90K - $125K/yr

Working knowledge of C++ and Python. QUALIFICATIONS * Bachelor's Degree in Computer Engineering, Software Engineering, or related field. * Minimum 5 years of relevant experience. * US Person required ...

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Senior Python Software Engineer information

See Greenville, SC salary details

$51.7K

$133.5K

$183.4K

How much do senior python software engineer jobs pay per year?

As of Jun 20, 2026, the average yearly pay for senior python software engineer in Greenville, SC is $133,498.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,200.00 and $153,700.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the salary of senior Python developer?

The salary of a senior Python software engineer typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. Skilled professionals with expertise in frameworks like Django or Flask and experience with cloud services may earn higher compensation.

Will AI replace Python coders?

AI tools can automate certain coding tasks, but Senior Python Software Engineers are essential for designing, developing, and maintaining complex software systems. AI is more likely to augment coding work rather than fully replace experienced developers, who bring problem-solving, creativity, and domain expertise that AI cannot replicate fully.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What engineers make $500,000?

Senior Python Software Engineers with extensive experience, specialized skills in areas like machine learning or data engineering, and working in high-paying industries such as finance or tech can earn $500,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially at large tech companies or startups with significant funding.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

Is it possible to make 300k as a software engineer?

Senior Python software engineers with extensive experience, specialized skills, and working in high-paying industries or companies can reach or exceed a $300,000 annual salary, especially with bonuses and stock options. Achieving this level often requires advanced knowledge of frameworks, cloud platforms, and a strong track record of project success.
What are popular job titles related to Senior Python Software Engineer jobs in Greenville, SC? For Senior Python Software Engineer jobs in Greenville, SC, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Greenville, SC look for? The top searched job categories for Senior Python Software Engineer jobs in Greenville, SC are:
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Senior Python Software Engineer jobs near you

Senior Software Engineer

TRULEO

Greenville, SC • On-site

$115K - $151K/yr

Full-time

This job post has expired today. Applications are no longer accepted.

Job description

Job Summary:
TRULEO builds the first case intelligence platform for law enforcement, and they are seeking a Senior Software Engineer to join their engineering team. In this full-stack role, you will work on customer-facing features, design APIs, and improve AI capabilities to help detectives solve cases more efficiently.
Responsibilities:
• Build and ship customer-facing features across the full stack (front end, back end, and data), and own them from design through production.
• Design and maintain the APIs and data models behind our core case-intelligence workflows.
• Develop and improve our AI capabilities
• Build and maintain the connectors that ingest, organize, and cross-reference data from the third-party systems detectives rely on.
• Run what you build in production, including the harder parts of rollout - migrations, backfills, feature flags, and debugging live systems.
• Work within our secure, compliant development process (SOC 2, FBI CJIS) and partner with Product to turn customer needs into features people actually use.
Qualifications:
Required:
• 7+ years of professional software engineering experience.
• Strong full-stack background, with production experience in React, TypeScript, Node.js, and PostgreSQL.
• Experience with Python, machine learning (ML), ML Ops
• Experience building AI-powered systems.
• Comfortable with cloud infrastructure and containerized deployments.
• A practical, self-directed engineer who communicates clearly and does well on a small team where everyone wears several hats.
• Able to work on-site in Greenville, SC, and to pass the background check required to work with criminal justice (CJIS) data.
Company:
TRULEO is an AI platform that delivers insights and automates decision-making to help businesses optimize performance and drive growth. Founded in 2021, the company is headquartered in Greenville, USA, with a team of 11-50 employees. The company is currently Early Stage.

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