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Senior Python Software Engineer Jobs in Columbia, SC

Robert Half

Senior Software Engineer

Irmo, SC · On-site

$100K - $131K/yr

We are looking for a Senior Software Engineer to create intelligent automation solutions that ... NET, and Python in enterprise development environments • Proven ability to design and integrate ...

Benelynk

Sr. Software Engineer

Columbia, SC · Remote

$150K - $175K/yr

SENIOR SOFTWARE ENGINEER POSITION SUMMARY We are seeking a Sr. Software Engineer and or Jr. Platform Architect to serve as technical lead responsible for day-to-day development, design, build, and ...

Unum UK

Senior Software Engineer - Java/J2EE

Columbia, SC · On-site

$115K - $152K/yr

The Senior Software Engineer is a key technical leader within an Agile team, partnering closely with the Technical Product Owner and Principal Software Engineer to ensure highquality, scalable ...

VOLT

Software Engineer III-1st shift

Hopkins, SC · On-site

$55 - $60/hr

As a Sr. Software Developer, you will: Job Overview: We are seeking a highly skilled Industrial ... Develop and maintain custom scripts using JavaScript, Python, VBScript, or C# to enhance system ...

Alpaca

Senior Software Engineer - Market Data

North, SC · On-site

$113K - $149K/yr

As a senior software engineer, you will help build and scale the systems and services that form the foundation of Alpaca and empower millions of users who are trading billions of dollars worth of ...

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All JobsSenior Python Software Engineer JobsSenior Python Software Engineer Jobs in Columbia, SC

Senior Python Software Engineer information

See Columbia, SC salary details

$50.9K

$131.3K

$180.4K

How much do senior python software engineer jobs pay per year?

As of Jun 19, 2026, the average yearly pay for senior python software engineer in Columbia, SC is $131,347.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,400.00 and $151,300.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the salary of senior Python developer?

The salary of a senior Python software engineer typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. Skilled professionals with expertise in frameworks like Django or Flask and experience with cloud services may earn higher compensation.

Will AI replace Python coders?

AI tools can automate certain coding tasks, but Senior Python Software Engineers are essential for designing, developing, and maintaining complex software systems. AI is more likely to augment coding work rather than fully replace experienced developers, who bring problem-solving, creativity, and domain expertise that AI cannot replicate fully.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What engineers make $500,000?

Senior Python Software Engineers with extensive experience, specialized skills in areas like machine learning or data engineering, and working in high-paying industries such as finance or tech can earn $500,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially at large tech companies or startups with significant funding.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

Is it possible to make 300k as a software engineer?

Senior Python software engineers with extensive experience, specialized skills, and working in high-paying industries or companies can reach or exceed a $300,000 annual salary, especially with bonuses and stock options. Achieving this level often requires advanced knowledge of frameworks, cloud platforms, and a strong track record of project success.
What are popular job titles related to Senior Python Software Engineer jobs in Columbia, SC? For Senior Python Software Engineer jobs in Columbia, SC, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Columbia, SC look for? The top searched job categories for Senior Python Software Engineer jobs in Columbia, SC are:
What cities near Columbia, SC are hiring for Senior Python Software Engineer jobs? Cities near Columbia, SC with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer jobs near you
Senior Software Engineer

Senior Software Engineer

Robert Half

Irmo, SC • On-site

$100K - $131K/yr

Full-time

Posted 15 days ago

Job description

We are looking for a Senior Software Engineer to create intelligent automation solutions that connect AI capabilities with core business processes. Based in Irmo, South Carolina, this role will focus on building dependable, scalable workflow applications that improve operational efficiency and support enterprise needs. The position offers the opportunity to work across engineering, data, and business teams to deliver practical AI-driven systems from concept through production.
Responsibilities:
• Create and enhance AI-enabled workflows and agent-based applications that support business automation goals
• Build integrations between enterprise platforms, business logic, and AI services to deliver efficient end-to-end solutions
• Develop coordinated multi-agent processes that manage task assignment, interaction, and execution across systems
• Lead the full engineering lifecycle, including solution design, coding, release management, performance tracking, and continuous improvement
• Establish resilient and observable architectures with strong attention to scalability, reliability, and maintainability
• Collaborate closely with technology, data, and operational stakeholders to translate requirements into production-ready applications
• Support cloud-based deployment and operational practices using modern DevOps and CI/CD approaches
• Contribute to API-driven development efforts and help optimize solutions running within Microsoft Azure environments• 5+ years of experience in software engineering, automation, or data-focused application development
• Strong programming experience with C#, .NET, ASP.NET, and Python in enterprise development environments
• Proven ability to design and integrate APIs, workflow services, and business system connections
• Hands-on experience with Microsoft Azure, including cloud application deployment and service integration
• Familiarity with large language models, AI workflow design, or agent-oriented development frameworks
• Experience using Git, CI/CD pipelines, and Azure DevOps or comparable development toolchains
• Ability to work effectively with cross-functional teams and deliver solutions aligned to business objectives
• Exposure to tools such as Azure AI, Power Platform, AutoGen, Semantic Kernel, or related DevOps/MLOps practices is a plus
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About Robert Half

Sourced by ZipRecruiter

Founded in 1948, Robert Half pioneered the idea of professional talent solutions to connect opportunities at great companies with highly skilled job seekers. As business needs changed, we evolved to offer specialized talent solutions for finance and accounting, technology, administrative and customer support, creative and marketing, and legal fields. In 2002, we introduced our subsidiary, Protiviti, a global independent risk consulting and internal audit service, to support companies as they faced more strategic business challenges.

Industry

Recruiting and staffing services

Company size

10,000+ Employees

Headquarters location

San Ramon, CA, US

Year founded

1948

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