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Senior Python Software Engineer Jobs in Durham, NC

NetApp

Senior Software Engineer

Morrisville, NC · On-site

$114K - $151K/yr

Job Summary As a Senior Software Engineer - Cloud Infrastructure, you will help build, operate, and ... Strong coding / scripting skills in Python, Go, or PowerShell. * Deep experience with Linux ...

Redhat

Senior Software Engineer

Raleigh, NC · On-site +1

$118K - $195K/yr

As a Senior Software Engineer, your main focus will be on designing, developing, testing and ... Experience with Python, Bash, or similar scripting languages * Experience with software testing, CI ...

Red Hat, LLC

Senior Software Engineer

Raleigh, NC · On-site

$118.60 - $195.68/hr

As a Senior Software Engineer, your main focus will be on designing, developing, testing and ... Experience with Python, Bash, or similar scripting languages. * Experience with software testing ...

ARA

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

They are seeking a Senior Software Engineer to develop software that connects physics-based ... g., Java, Python, C++, or TypeScript) for software development and/or data analysis. • ...

Verily Health

Senior Staff Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

The Senior Staff Software Engineer will provide technical leadership and hands-on software ... Java, Python, JavaScript, C#, Go, Objective-C, and/or Swift) Preferred : • Clear written ...

DomainTools

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect ... We are looking for someone with a strong background in Python, Rust, GoLang, and cloud ...

DomainTools

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

Description DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This ... We are looking for someone with a strong background in Python, Rust, GoLang, and cloud ...

DomainTools

Senior Software Engineer

Raleigh, NC · Remote

$125K - $165K/yr

DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect ... We are looking for someone with a strong background in Python, Rust, GoLang, and cloud ...

DomainTools

Senior Software Engineer

Raleigh, NC · On-site +1

$119K - $157K/yr

DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect ... We are looking for someone with a strong background in Python, Rust, GoLang, and cloud ...

Targan Inc

Senior Vision Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

The Senior Vision Software Engineer will actively communicate with project stakeholders and the ... Proficiency in Python and C# for software development. * Proficiency in SQL and experience with ...

WiTH Collective

Senior Software Engineer (Remote)

Cary, NC · On-site

$87.84 - $136.50/hr

The Senior Software Engineer will work in a fast-paced environment as part of an agile team and ... Using Python (or Java) and .NET preferred * Using Fast API web frameworks or similar (e.g., Flask ...

Pearson

Senior Software Engineer

Durham, NC · On-site

$118K - $156K/yr

Pearson, the world's leading learning company, is hiring a Senior Software Engineer to play a key ... Strong Python and backend/platform engineering-async services, typed code, and clean architecture.

Korn Ferry

Senior Software Engineer - LexisNexis

Raleigh, NC · On-site

$119K - $157K/yr

RELX Inc. is seeking a Senior Software Engineer to join their LexisNexis CounselLink team, which ... Preferred : • Experience with Python development. • Experience integrating GenAI capabilities ...

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Showing results 21-40

All JobsPython Software Engineer JobsSenior Python Software Engineer JobsSenior Python Software Engineer Jobs in Durham, NC

Senior Python Software Engineer information

See Durham, NC salary details

$53.1K

$137.2K

$188.4K

How much do senior python software engineer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python software engineer in Durham, NC is $137,192.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,400.00 and $158,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by senior Python software engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a senior Python software engineer?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a senior Python software engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in Durham, NC? For Senior Python Software Engineer jobs in Durham, NC, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Durham, NC look for? The top searched job categories for Senior Python Software Engineer jobs in Durham, NC are:
What cities near Durham, NC are hiring for Senior Python Software Engineer jobs? Cities near Durham, NC with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer jobs near you
Infographic showing various Senior Python Software Engineer job openings in Durham, NC as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 12% Part Time, and 3% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $137,192 per year, or $66 per hour.

Senior Software Engineer

NetApp

Morrisville, NC • On-site

$114K - $151K/yr

Full-time

Medical, Life, Retirement, PTO

Re-posted 4 days ago

NetApp rating

9.4

Company rating: 9.4 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

2nd of 485 rated business services

Job description

Job Summary

As a Senior Software Engineer - Cloud Infrastructure, you will help build, operate, and scale mission-critical cloud services that support NetApp's SaaS and IaaS offerings. You will work across the full service lifecycle-from design and deployment through production operations and continuous improvement-at the intersection of software engineering, infrastructure, and operations.

You will improve reliability, scalability, and operational efficiency through automation, observability, and strong engineering practices. This role supports cloud-native services built on microservices and Kubernetes-based architectures and partners closely with NetApp teams and cloud providers including Microsoft Azure.

This is a high-impact opportunity for an engineer who enjoys solving distributed-systems challenges, eliminating operational toil, and improving the resilience, performance, and security of cloud services at scale.

Responsibilities
  • Build automation to improve operational efficiency and reduce risk.
  • Improve reliability, scalability, and deployment velocity for cloud services.
  • Troubleshoot complex production issues across the full stack.
  • Lead incident response and root cause analysis for critical service events.
  • Monitor and optimize service health, availability, latency, and performance.
  • Operate Kubernetes- and container-based cloud infrastructure.
  • Provide advanced tier 2/3 support for cloud data services.
  • Strengthen security posture and resolve complex security issues.
  • Create and maintain runbooks and operational documentation.
  • Influence architecture and implementation decisions through production insight.
Job Requirements
  • U.S. Citizenship or Permanent Residence with Green Card status mandatory.
  • 8+ years of experience in software, infrastructure, or site reliability engineering.
  • Full-Stack Engineer Experience Required.
  • Strong coding / scripting skills in Python, Go, or PowerShell.
  • Deep experience with Linux, Kubernetes, containers, and distributed systems.
  • Experience with Azure, AWS, or Google Cloud.
  • Experience using Artificial Intelligence to accelerate automation development and optimize processes. Ability to derive actionable business intelligence from structured and unstructured logs, events, traces, and metrics using AI and MCP-enabled agentic workflows.
  • Strong understanding of DevOps / SRE practices.
  • Excellent troubleshooting skills across infrastructure and application layers. 
Education

Bachelor of Science Degree in Computer Science, a master's degree; or equivalent experience is required.

Compensation:
The target salary range for this position is 196,350 - 292,600 USD. The salary offered will be determined by the candidate's location, qualifications, experience, and education and may be outside of this range. Final compensation packages are competitive and in line with industry standards, reflecting a variety of factors, and include a comprehensive benefits package. This may cover Health Insurance, Life Insurance, Retirement or Pension Plans, Paid Time Off, various Leave options, Performance-Based Incentives, employee stock purchase plan, and/or restricted stocks (RSU's), with all offerings subject to regional variations and governed by local laws, regulations, and company policies. Benefits may vary by country and region, and further details will be provided as part of the recruitment process. 

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