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Senior Python Software Engineer Jobs in Durham, NC

Compunnel

Senior Python Developer

Durham, NC · On-site

$117K - $158K/yr

Job Summary The Senior Python Developer is responsible for designing, developing, and maintaining ... Required Qualifications • 7+ years of professional software engineering experience. • Strong ...

ARA

Senior Software Engineer

Raleigh, NC · On-site

$108K - $142K/yr

Proven experience with programming languages (e.g., Java, Python, C++, or TypeScript) for software ... Senior Software Engineer Preferences: Above all, we value passion, a continuous desire to learn ...

Berriehill Research

Senior Software Engineer

Raleigh, NC

$108K - $142K/yr

Proven experience with programming languages (e.g., Java, Python, C++, or TypeScript) for software ... Senior Software Engineer Preferences: Above all, we value passion, a continuous desire to learn ...

First Citizens Bank

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

Overview This position is HYBRID in Raleigh, NC We are seeking a Senior Software Engineer with ... Proficiency in AWS Services (e.g., EC2, S3, Lambda, RDS), Snowflake, dbt, Python and SQL * Hands-on ...

First Citizens Bank

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

Overview This position is HYBRID in Raleigh, NC We are seeking a Senior Software Engineer with ... Advanced proficiency in Python and SQL. * Advanced experience developing and supporting ETL/ELT ...

First Citizens Bank

Senior Software Engineer

Raleigh, NC · On-site

$119K - $157K/yr

Overview This position is HYBRID in Raleigh, NC We are seeking a Senior Software Engineer with ... Advanced proficiency in Python and SQL. * Advanced experience developing and supporting ETL/ELT ...

Clutch Canada

Senior Software Engineer

Durham, NC · On-site

$120 - $160/hr

Senior Software Engineer This role is onsite in Durham, North Carolina with 2-3 days in-office ... We build our backend in Python and our front end in Angular. The bar is high, because when a ...

Garmin International, Inc.

Senior Software Engineer

Cary, NC · On-site

$124K - $164K/yr

Overview We are seeking a full-time Senior Software Engineer at Garmin's Cary, North Carolina ... C, C++, Python, Assembly language, or other selected languages for new and existing products ...

Garmin Ltd.

Senior Software Engineer

Cary, NC · On-site

$120 - $180/hr

Overview We are seeking a full-time Senior Software Engineer at Garmin's Cary, North Carolina ... C, C++, Python, Assembly language, or other selected languages for new and existing products ...

Socket.dev

Senior Software Engineer - RTP

Raleigh, NC · On-site

$120 - $160/hr

VAST Data is looking to add a Senior Developer to our growing team! This is a unique opportunity to ... Strong development skills in C, C++, or Python * Systems programming experience and the ability to ...

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All JobsPython Software Engineer JobsSenior Python Software Engineer JobsSenior Python Software Engineer Jobs in Durham, NC

Senior Python Software Engineer information

See Durham, NC salary details

$53.1K

$137.2K

$188.4K

How much do senior python software engineer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python software engineer in Durham, NC is $137,192.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,400.00 and $158,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by senior Python software engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a senior Python software engineer?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a senior Python software engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in Durham, NC? For Senior Python Software Engineer jobs in Durham, NC, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Durham, NC look for? The top searched job categories for Senior Python Software Engineer jobs in Durham, NC are:
What cities near Durham, NC are hiring for Senior Python Software Engineer jobs? Cities near Durham, NC with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer jobs near you
Infographic showing various Senior Python Software Engineer job openings in Durham, NC as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 12% Part Time, and 3% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $137,192 per year, or $66 per hour.

Senior Python Developer

Compunnel

Durham, NC • On-site

$117K - $158K/yr

Contractor

Re-posted 13 days ago

Job description

Job Summary
The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations, and system modernization. This role supports a core monolithic platform built with Python and Django while driving architectural improvements, mentoring engineers, and delivering scalable, high-quality software solutions. The ideal candidate has extensive experience with Python, Django, TypeScript, API development, and full-stack application engineering.
Key Responsibilities
• Design, develop, and maintain enterprise applications using Python and Django.
• Enhance and support a core monolithic application responsible for processing and orchestration.
• Design, develop, and maintain RESTful APIs and integration services for internal systems.
• Build and enhance full-stack applications with a strong emphasis on backend development and TypeScript.
• Develop and maintain integrations supporting enterprise platform functionality.
• Perform system modernization, performance improvements, and platform stability enhancements.
• Participate in architecture discussions and contribute to technical design decisions.
• Troubleshoot production issues, perform root cause analysis, and implement permanent solutions.
• Participate in production support and on-call rotations.
• Collaborate with cross-functional teams including product, platform, and business stakeholders.
• Mentor junior engineers and promote software engineering best practices.
• Communicate technical concepts effectively with both technical and non-technical stakeholders.
• Contribute to continuous improvement initiatives and engineering standards.
Required Qualifications
• 7+ years of professional software engineering experience.
• Strong hands-on experience with Python development.
• Strong experience developing enterprise applications using Django.
• Full-stack development experience with a strong backend focus.
• Extensive experience developing RESTful APIs and service-oriented architectures.
• Strong experience with TypeScript for frontend and backend development.
• Experience working with MySQL databases.
• Strong knowledge of software architecture, system design, and application development best practices.
• Strong analytical, debugging, troubleshooting, and problem-solving skills.
• Excellent communication, collaboration, and mentoring skills.
• Ability to independently solve complex technical problems and deliver scalable solutions.
Preferred Qualifications
• Experience in healthcare technology, clinical laboratory, or genomics environments.
• Experience with AWS cloud services and cloud-native application development.
• Experience with Docker, Kubernetes, or containerized application deployments.
• Experience with Infrastructure as Code tools such as Terraform.
• Experience designing and maintaining enterprise API platforms.
• Familiarity with AI-assisted development tools such as Claude or Codex.
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About Compunnel

Sourced by ZipRecruiter

Compunnel is a well-known company located in Plainsboro, NJ, US, recognized in the industry of IT Services and Solutions. Established in 1989, Compunnel offers a suite of services that help businesses integrate technology efficiently into their operations, a recognizable name in the IT solutions sphere for over three decades. The company’s service portfolio includes Digital Transformation, Business Intelligence, Cloud Services, Cybersecurity, and Application Modern Services, among others. Guided by its mission "to innovate with industry-leading digital solutions and disruptive tech strategies for unimagining business growth," the company underlines its commitment to offering out-of-the-box solutions to its clients. Remarkable achievements of the company include serving more than 30 Fortune 500 companies and providing job opportunities for over 50,000 individuals.

Industry

It services

Company size

501 - 1,000 Employees

Headquarters location

Plainsboro, NJ, US

Year founded

1994

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