1

Senior Python Engineer Jobs in Raleigh, NC (NOW HIRING)

Sr. Python Developer

Durham, NC ยท On-site

$110K - $148K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Job#: 3039740 Sr. Python Developer Location: Durham, North Carolina - Hybrid, 3x per week onsite ... Software Engineer to support a core monolithic system that orchestrates lab order intake ...

Senior AI Developer

Raleigh, NC ยท On-site

$118K - $158K/yr

NCDIT-T Web Systems is seeking a Senior AI Enablement Engineer with strong experience in C#, Vue.js, Python, and Azure AI . The role focuses on integrating Azure OpenAI, Copilot Studio, and other AI ...

Python/AI Product Engineer

Durham, NC ยท Hybrid

  • Medical

  • Dental

  • Retirement

  • PTO

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

Python/AI Product Engineer

Durham, NC ยท On-site

  • Medical

  • Dental

  • Retirement

  • PTO

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

GenAI Python Systems Engineer -Senior Manager

Raleigh, NC ยท On-site

$124K - $280K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... Level Senior Manager & Summary At PwC, our people in data and analytics engineering focus on ... is a plus - Proficient in Python and structured/unstructured data - Proficient in SQL and ...

Senior Advanced AI Research Engineer

Raleigh, NC ยท On-site

$101K - $139K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

You Are: As a Senior Advanced AI Research Engineer, you sit at the boundary between AI systems ... You are a strong Python engineer who can move fluently between an experiment and a well-structured ...

Senior Software Engineer - Python

Raleigh, NC ยท On-site

$110 - $270/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

The Role As Senior Software Engineer for a new product within Veeva, you will be a founding member ... Python development required). * Enterprise SaaS Leader: Extensive experience developing ...

Senior Engineer - Data Discovery

Raleigh, NC ยท On-site

$103K - $140K/yr

This Sr. Engineer is responsible for the design, architecture and deployment of data discovery and ... Requirements: * 10 years full-stack engineering experience (Must have experience in Python and Java)

Senior AI/LLM Engineer - Remote

Raleigh, NC ยท On-site

$53.75 - $69.25/hr

  • Dental

  • Vision

  • Life

  • Retirement

REMOTE - Senior AI/LLM Engineer (Generative AI Solutions) Job Title: Senior AI/LLM Engineer ... The ideal candidate will have strong expertise in Python development, Retrieval-Augmented ...

next page

Showing results 1-20

Senior Python Engineer information

See Raleigh, NC salary details

$53.5K

$138K

$189.6K

How much do senior python engineer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior python engineer in Raleigh, NC is $138,012.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,100.00 and $158,900.00 per year, depending on experience, location, and employer.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What are the most commonly searched types of Python Engineer jobs in Raleigh, NC?

The most popular types of Python Engineer jobs in Raleigh, NC are:

What are popular job titles related to Senior Python Engineer jobs in Raleigh, NC?

For Senior Python Engineer jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Senior Python Engineer jobs in Raleigh, NC look for?

The top searched job categories for Senior Python Engineer jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Senior Python Engineer jobs?

Cities near Raleigh, NC with the most Senior Python Engineer job openings:

Infographic showing various Senior Python Engineer job openings in Raleigh, NC as of August 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution, with an average salary of $138,012 per year, or $66.4 per hour.

Sr. Python Developer

Apex Systems

Durham, NC โ€ข On-site

$110K - $148K/yr

Other

Medical, Dental, Vision, Life, Retirement

This job post hasย expired today.ย Applications are no longer accepted.


Job description

Job#: 3039740
Job Description:
Sr. Python Developer
Location: Durham, North Carolina - Hybrid, 3x per week onsite
Duration: 6 Month Contract to Hire
Role Overview
We are seeking a Senior Software Engineer to support a core monolithic system that orchestrates lab order intake, processing, and interpretation. This role requires an individual who can take ambiguous, complex problems and drive them to completion. The successful candidate will act as a technical leader, mentoring other engineers and raising the bar for the team in architecture and execution, with a heavy focus on integration work connecting internal systems with lab pipelines.
Key Responsibilities
  • Own and deliver projects across product, platform, and stakeholder teams.
  • Design, develop, and maintain a central, monolithic system built on Python and Django.
  • Develop and enhance system integrations and core platform functionality with a strong emphasis on API-driven architecture.
  • Perform foundational engineering work focused on system improvements, stability, and modernization.
  • Provide production support, including participating in an on-call rotation and troubleshooting bugs.
  • Mentor teammates and elevate the team's technical execution standards.
  • Communicate clearly with both technical and non-technical audiences.
Required Qualifications
Experience: A minimum of 7+ years of professional software engineering experience is required. Candidates must demonstrate strong experience in system design, development, and real-world application architecture.
Technical Skills: Proficiency in Python and Django is mandatory. Candidates must have full-stack experience with a strong backend emphasis, including heavy API development and experience with TypeScript and MySQL.
Education: A formal degree is not required. Experience and technical skill are prioritized.
Preferred Qualifications
  • Experience in healthcare technology, clinical laboratory, or genomics industries.
  • Knowledge of AWS-native environments and cloud platforms.
  • Familiarity with containerization, Kubernetes, or infrastructure-as-code tools like Terraform.
  • Experience designing and maintaining API platforms that serve multiple internal consumers.
  • Familiarity with AI development tools such as Claude or Codex.
Work Environment
This is a fully remote position. The team is collaborative and engineers are expected to contribute ideas and participate in design decisions. The team is globally distributed across multiple time zones.
Eligibility
Visa sponsorship is not available for this position now or in the future.
Everforth Apex is a world-class IT services company that serves thousands of clients across the globe. When you join Everforth Apex, you become part of a team that values innovation, collaboration, and continuous learning. We offer quality career resources, training, certifications, development opportunities, and a comprehensive benefits package. Our commitment to excellence is reflected in many awards, including ClearlyRateds Best of Staffing in Talent Satisfaction in the United States and Great Place to Work in the United Kingdom and Mexico.
Everforth Apex uses a virtual recruiter as part of the application process. Click for more details. By applying for this job, you agree to receive calls, AI-generated calls, text messages, or emails from Everforth Apex and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy at
Everforth Apex Benefits Overview: Everforth Apex offers a range of supplemental benefits, including medical, dental, vision, life, disability, and other insurance plans that offer an optional layer of financial protection. We offer an ESPP (employee stock purchase program) and a 401K program which allows you to contribute typically within 30 days of starting, with a company match after 12 months of tenure. Everforth Apex also offers a HSA (Health Savings Account on the HDHP plan), a SupportLinc Employee Assistance Program (EAP) with up to 8 free counseling sessions, a corporate discount savings program and other discounts. In terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA. Everforth Apex has a dedicated customer service team for our Consultants that can address questions around benefits and other resources, as well as a certified Career Coach. You can access a full list of our benefits, programs, support teams and resources within our 'Welcome Packet' as well, which an Everforth Apex team member can provide.
Everforth Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Everforth Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law.
If you require an accommodation under the Americans with Disabilities Act to participate in an interview with a virtual recruiter or to use our website for a search or application, please contact our Benefits Department at or . Please note that this contact information is strictly to be used for medical ADA accommodations and that no other inquiries will be answered.
UnitedHealthcare creates and publishes the Transparency in Coverage Machine-Readable Files on behalf of Everforth Apex Systems.