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Senior Python Engineer Jobs in Raleigh, NC (NOW HIRING)

Senior Python Developer

Durham, NC · On-site

$117K - $158K/yr

Job Summary The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations ...

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

Senior Engineer - Data Discovery

Raleigh, NC

$103K - $140K/yr

This Sr. Engineer is responsible for the design, architecture and deployment of data discovery and ... Requirements: * 10 years full-stack engineering experience (Must have experience in Python and Java)

Senior Firmware Engineer

Durham, NC · On-site

$115K - $152K/yr

Durham NC Jobs, Senior Firmware Engineer, C/C++, VHDL, Python, Git, SVN, DSP Algorithms, Mathematical Models, FPGA, CPDL, Microprocessors, Healthcare, North Carolina Recruiters, Information ...

Senior Data Engineer

Durham, NC · On-site

$102K - $139K/yr

... a Senior Data Enablement Engineer to lead the evolution of our internal tools and test data ... Strong hands-on skills in SQL and Python * Knowledge of data modeling, data relations, data flows ...

Senior Structural Engineer

Raleigh, NC · On-site

$97K - $132K/yr

About the Role As a Senior Structural Engineer, you'll lead the structural effort across projects ... VBA and Python for design automation) to deliver and document designs. * Mentor engineers and ...

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Senior Python Engineer information

See Raleigh, NC salary details

$53.5K

$138K

$189.6K

How much do senior python engineer jobs pay per year?

As of Jul 8, 2026, the average yearly pay for senior python engineer in Raleigh, NC is $138,012.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,100.00 and $158,900.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What are the most commonly searched types of Python Engineer jobs in Raleigh, NC? The most popular types of Python Engineer jobs in Raleigh, NC are:
What job categories do people searching Senior Python Engineer jobs in Raleigh, NC look for? The top searched job categories for Senior Python Engineer jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Senior Python Engineer jobs? Cities near Raleigh, NC with the most Senior Python Engineer job openings:
Sr. Python Developer

$117K - $158K/yr

Full-time, Contractor

Posted 9 days ago


Job description

Sr. Python Developer | Durham, North Carolina, United States Sr. Python Developer (Remote, Contract-to-Hire) Durham, NC | 6-Month Contract-to-Hire | No Visa Sponsorship About the Role Join a forward-thinking engineering team as a Sr. Python Developer, supporting mission-critical systems that drive lab order intake, processing, and interpretation. In this high-impact, fully remote position, you'll solve complex, ambiguous problems, lead key integration projects, and set the technical standard for a collaborative, globally distributed team. This is a contract-to-hire opportunity for professionals authorized to work in the U.S. without sponsorship. Responsibilities - Own and deliver end-to-end projects across product and platform teams - Design, build, and maintain a central monolithic system using Python and Django - Develop robust API-driven system integrations with a strong backend focus - Modernize and stabilize core platform functionality for long-term scalability - Provide production support and participate in on-call rotations - Mentor junior engineers and elevate team performance through technical leadership - Communicate technical solutions clearly to stakeholders across technical levels Required Skills and Experience - 7+ years of professional software engineering experience - Advanced proficiency in Python and Django - Strong backend/full-stack development experience, including API design - Solid TypeScript skills (front and backend development) - Experience working with MySQL databases - Demonstrated expertise in system architecture and integration - Authorized to work in the U.S. without current or future sponsorship Preferred Skills - Experience in healthcare, clinical laboratory, or genomics technology - Familiarity with AWS-native environments and cloud platforms - Exposure to containerization, Kubernetes, or infrastructure-as-code (e.g., Terraform) - Experience designing and maintaining multi-consumer API platforms - Knowledge of AI tools (e.g., Claude, Codex) Benefits - Competitive contract compensation with potential for full-time hire - 100% remote work; collaborate with a distributed, innovative engineering team - Opportunity to work on cutting-edge, impactful systems in the health tech space - Fast-paced environment with mentorship and career growth opportunities How to Apply Ready to elevate your career and technical impact? Apply now with your resume and a summary of relevant experience.

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About Indotronix

Sourced by ZipRecruiter

In 1986, Indotronix established itself in the staffing space. 22 years later, Avani entered the scene, offering consulting and technology development. Finally, in 2016, the two joined forces to begin delivering talent across all areas, from Staffing to Consulting to unique platform development.

Industry

Recruiting and staffing services

Company size

1,001 - 5,000 Employees

Headquarters location

Rochester, NY, US