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Senior Python Developer Jobs in Indiana, PA (NOW HIRING)

The Biopôle

Senior Software Engineer

Indiana, PA · On-site

$100 - $130/hr

Senior Software Engineer About the role As a Senior Software Engineer within the Application and ... DevOps. * Proficiency in Python and SQL, with knowledge of data governance, data security ...

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Senior Python Developer information

See Indiana, PA salary details

$50.3K

$129.8K

$178.2K

How much do senior python developer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for senior python developer in Indiana, PA is $129,758.00, according to ZipRecruiter salary data. Most workers in this role earn between $111,000.00 and $149,400.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are popular job titles related to Senior Python Developer jobs in Indiana, PA?

For Senior Python Developer jobs in Indiana, PA, the most frequently searched job titles are:

What cities near Indiana, PA are hiring for Senior Python Developer jobs?

Cities near Indiana, PA with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Indiana, PA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $129,758 per year, or $62.4 per hour.

Senior Software Engineer

The Biopôle

Indiana, PA • On-site

$100 - $130/hr

Other

Posted 13 days ago

Job description

Senior Software Engineer

About the role

As a Senior Software Engineer within the Application and Data team, you will contribute to the technical bridge between the Dexter robotic system and its cloud analytics platform. You will design and develop C++/Qt software modules, implement remote monitoring and data connectivity solutions, and build scalable data pipelines for ingestion, processing, and visualization within Azure/Databricks environments.

Key requirements

  • Master’s or Bachelor’s degree in Computer Science, Electronics, Electrical Engineering, or related discipline.
  • 10+ years of software engineering experience, including data engineering or connectivity solutions.
  • Expert in C++ for Windows and highly proficient in Qt; strong expertise in Databricks, Azure, Terraform, and Azure DevOps.
  • Proficiency in Python and SQL, with knowledge of data governance, data security principles, and medical device quality management systems.
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