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Senior Python Developer Jobs in Harrisburg, PA (NOW HIRING)

*Cummins Business

Software Developer 2

Lemoyne, PA · On-site

Job Title: Senior Software Developer Location: [Specify Location or Remote] Employment Type ... Proficiency in programming languages such as [e.g., Python, Java, JavaScript, C#, etc.

Leverage Technologies

Senior Okta Engineer

Harrisburg, PA

$103K - $141K/yr

A Senior IAM (Okta) Engineer is a senior-level security and systems architect who designs, deploys ... Python or Powershell. • Knowledge of directory services like Active Directory, and LDAP ...

New

Datavant

Senior Software Engineer

Harrisburg, PA

$180K - $220K/yr

... Senior Software Engineer, you will lead major initiatives that advance Datavant's platform ... Python, Go, Java; microservices; REST and GraphQL * Frontend: TypeScript, React, Next.js

SmartIPlace

Senior DevSecOps Engineer

Harrisburg, PA · On-site

$55 - $60/hr

CI/CD authoring in GitHub Actions and Azure DevOps. * Proficient in Python and Bash, with PowerShell for Windows automation. * Able to read Java and C# to integrate and tune SAST/SCA. * Practical ...

DP World

Senior Network Engineer

York, PA · Hybrid

$102K - $140K/yr

The Senior Network Engineer plays a critical role in enabling this growth by leading the resilience ... Python, Ansible, APIs), with a focus on scalability and operational efficiency * Experience ...

DP World

Senior Network Engineer

York, PA · Hybrid

$102K - $140K/yr

The Senior Network Engineer plays a critical role in enabling this growth by leading the resilience ... Python, Ansible, APIs), with a focus on scalability and operational efficiency * Experience ...

DP World

Senior Network Engineer

York, PA · On-site

$102K - $140K/yr

The Senior Network Engineer plays a critical role in enabling this growth by leading the resilience ... Python, Ansible, APIs), with a focus on scalability and operational efficiency * Experience ...

BAE Systems

Programmer Anst Sr

York, PA · On-site

$88K - $149K/yr

Key Responsibilities As a Sr Programmer Analyst, you will play a critical role in designing ... Proficiency in programming languages such as Java, JavaScript, Python, and SQL, as well as ...

DP World

Senior Network Engineer

Carlisle, PA · On-site

$101K - $138K/yr

The Senior Network Engineer plays a critical role in leading the resilience, security, and ... Python, Ansible, APIs), with a focus on scalability and operational efficiency • Experience ...

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All JobsSenior Python Developer JobsSenior Python Developer Jobs in Harrisburg, PA

Senior Python Developer information

See Harrisburg, PA salary details

$54.3K

$140.2K

$192.5K

How much do senior python developer jobs pay per year?

As of Jun 18, 2026, the average yearly pay for senior python developer in Harrisburg, PA is $140,176.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,000.00 and $161,400.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a Senior Python Developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

What are the key skills and qualifications needed to thrive as a Senior Python Developer, and why are they important?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by Senior Python Developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Harrisburg, PA? The most popular types of Python Developer jobs in Harrisburg, PA are:
What job categories do people searching Senior Python Developer jobs in Harrisburg, PA look for? The top searched job categories for Senior Python Developer jobs in Harrisburg, PA are:
What cities near Harrisburg, PA are hiring for Senior Python Developer jobs? Cities near Harrisburg, PA with the most Senior Python Developer job openings:
Senior Python Developer jobs near you
Senior Full-Stack Python Engineer (25% onsite)

Senior Full-Stack Python Engineer (25% onsite)

Info-Matrix Corporation

Middletown, PA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 6 days ago

Job description

Job Description
Info-Matrix is seeking a Senior Full-Stack Python Engineer with extensive experience in systems driven by Optical Character Recognition (OCR) and Computer Vision.This hands-on software engineering role focuses on building and scaling production systems that process images, perform OCR, and deliver results via robust APIs and client-facing applications.
Description of Duties
Backend & OCR Systems
  • Design, implement, and maintain workflowsfor Optical Character Recognition (OCR) and image processing, covering everythingfrom data ingestion to evaluation and output.
  • Develop scalable backend servicesin Python using Fast API.
  • Integrate with third-party OCR enginesthrough REST APIs, managing retries, errors, and fallback strategies.
  • Implement preprocessing techniquesand quality improvement measures.
  • Contribute to improving OCR accuracyby utilizing feedback from manual reviews and downstream validation processes.
  • Design data models and storage solutionsfor OCR results, metadata, and audit trails using PostgreSQL.

Distributed & Cloud Architecture
  • Build message-driven services usingAzure Service Bus for asynchronous processing.
  • Deploy and operate services on Azure,including AKS.
  • Containerize applications using Podmanand support CI/CD pipelines.
  • Contribute to system scalability,fault tolerance, and observability.

Full-Stack Skills
  • Develop and maintain React-based webapplications for internal and client-facing tools.
  • Implement responsive User Interfacecomponents using JavaScript / React.
  • Collaborate closely with backend servicesto integrate OCR functionality into the UI.
  • Understand and work with HTTP/HTTPS,authentication flows, and API contracts.

Engineering Leadership
  • Expert in Object Oriented Programming(OOP) applying abstraction, encapsulation, inheritance, and polymorphismto design scalable, reusable and loosely coupled systems aligned with SOLID(Single-responsibility, Open-closed, LiskovSubstitution, Interface Segregation, Dependency Inversion) principlesand guiding the team through code reviews and design standards.
  • Participate in architectural decisionsand technical design reviews.
  • Mentor junior engineers and help raiseoverall engineering standards.
  • Fully document all created work associated with this position, including technical and functional designs and diagrams, test plans, test scripts, impact analysis reports, lessons learned, best practices for others to follow, plus any other documentation as required by the client.This documentation shall follow the format and / or templates as instructed by the client.
  • Develop and maintain productive relationships with technology staff, business owners, project sponsors, vendors, and key clients.
  • Lead and participate in project team activities for system work efforts related to enterprise systems.
  • Work independently to accomplish the tasks and duties assigned.
  • Adhere to and follow all client standards, policies, and procedures.
  • Utilize various software and/or technology tools to perform job duties.
  • Perform tasks and other duties as related to this position and role and assigned by the client.

Requirements
The ideal candidate will have a strong Python background and the ability to develop backend services from start to finish, while also contributing to the frontend when necessary.This position lies at the intersection of backend systems, computer vision and OCR pipelines, distributed services, and modern frontend delivery.
  • Python: an expert level in Python with 8+years' experience implementing and supporting production systems.
  • FastAPI: 5+ years' experience with FastAPIor equivalent Python API frameworks.
  • OCR / Computer Vision: 5+ years of experience working with OCR and computer vision technologies, with a strong understanding of domain-specific applications.
  • PostgreSQL / SQL: Proficiency in schema design, query writing, and performance optimization.
  • JavaScript + React, HTML/CSS: Proven experience in production-level frontend development.
  • Azure cloud, Azure Service Bus: Knowledge of Azure cloud services or equivalent messaging systems.
  • AKS / Kubernetes: Hands-on experience with container orchestration using AKS or Kubernetes.
  • Linux environments: Strong understanding and practical experience working in Linux environments.
  • Proficiency in REST API designand integration.
  • Experience with JSON-baseddata exchange.
  • Expertise in containerized developmentand deployment workflows.
  • Knowledge of secure API design andoperational best practices.

Additional Desired Skills
  • Experience with AI/ML pipelines related to OCR or image processing.
  • Exposure to vector databases (e.g., Qdrant) and embedding-based similarity search.
  • Familiarity with PyTorch / ONNX for learned image enhancement or embeddings.
  • Knowledge of vehicle fingerprinting,multi-view embeddings, or related CV problems.
  • Security best practices around PIIhandling, image storage, and access control.

Benefits
Experience a workplace where people are the X-Factor! At Info-Matrix, we believe our greatest strength is our team-a diverse group of passionate professionals united by a drive to solve real-world business challenges through innovative technology solutions. Our culture is built on integrity, teamwork, and a commitment to excellence, fostering an environment where every voice is valued and every contribution matters!
Comprehensive Benefits Offered by Info-Matrix
  • Health & Wellness: Customized Medical,Dental, and Vision Plans
  • Paid Time Off: Generous PTO &11 paid holidays
  • Info-Matrix Paid Coverage: Short-term andlong-term disability, life insurance, and AD&D insurance.
  • Retirement Savings Offering: 401(k) plan withcompany match

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