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Senior Python Developer Jobs in Cincinnati, OH (NOW HIRING)

Medpace

Senior Data Engineer

Cincinnati, OH · On-site

$103K - $140K/yr

The Senior Data Engineer will work within the Information Technology team to support data ... of Python • Knowledge of C# • Knowledge of Azure development Company : Medpace, Inc., a ...

Honeywell

Sr Advanced Cloud Developer

Mason, OH

$53 - $72.50/hr

We are seeking a highly experienced Sr Advanced Cloud Developer with deep expertise in cloudnative ... Proficiency in Python and at least one additional language (Java, Scala, Go, C#, or TypeScript)

Honeywell

Sr Advanced Cloud Developer

Mason, OH

$53 - $72.50/hr

We are seeking a highly experienced Sr Advanced Cloud Developer with deep expertise in cloudnative ... Proficiency in Python and at least one additional language (Java, Scala, Go, C#, or TypeScript)

US Bank

Senior AI Platform Engineer

Cincinnati, OH · On-site

$53 - $68.25/hr

Job Summary The Senior Engineer (Generative AI) is responsible for designing, developing, and ... Develop scalable applications using Python and microservices-based architectures * Apply secure ...

System One

Sr. Site Reliability Engineer

Cincinnati, OH · On-site

$54.75 - $72.75/hr

Senior Site Reliability Engineer (SRE) Location: Cincinnati, OH (Hybrid - 3 days onsite/week) Type ... Scripting/programming proficiency in Python, Go, Bash, or PowerShell . * Production experience with ...

System One

Sr. Site Reliability Engineer

Cincinnati, OH · On-site

$54.75 - $72.75/hr

Senior Site Reliability Engineer (SRE) Location: Cincinnati, OH (Hybrid - 3 days onsite/week) Type ... Scripting/programming proficiency in Python, Go, Bash, or PowerShell . * Production experience with ...

System One

Sr. Site Reliability Engineer

Cincinnati, OH · On-site

$54.75 - $72.75/hr

Senior Site Reliability Engineer (SRE) Location: Cincinnati, OH (Hybrid - 3 days onsite/week) Type ... Scripting/programming proficiency in Python, Go, Bash, or PowerShell . * Production experience with ...

System One

Sr. Site Reliability Engineer

Cincinnati, OH · On-site

$54.75 - $72.75/hr

Senior Site Reliability Engineer (SRE) Location: Cincinnati, OH (Hybrid - 3 days onsite/week) Type ... Scripting/programming proficiency in Python, Go, Bash, or PowerShell . * Production experience with ...

System One

Sr. Site Reliability Engineer

Cincinnati, OH · On-site

$54.75 - $72.75/hr

Senior Site Reliability Engineer (SRE) Location: Cincinnati, OH (Hybrid - 3 days onsite/week) Type ... Scripting/programming proficiency in Python, Go, Bash, or PowerShell . * Production experience with ...

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$52.8K

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How much do senior python developer jobs pay per year?

As of Jul 8, 2026, the average yearly pay for senior python developer in Cincinnati, OH is $136,222.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,600.00 and $156,900.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a Senior Python Developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

What are the key skills and qualifications needed to thrive as a Senior Python Developer, and why are they important?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by Senior Python Developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
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Senior Python Developer jobs near you
Senior Data Engineer

Senior Data Engineer

Medpace

Cincinnati, OH • On-site

$103K - $140K/yr

Full-time

Re-posted 5 days ago

Medpace rating

8.5

Company rating: 8.5 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

13th of 58 rated research

Job description

Job Summary:
Medpace is a full-service clinical contract research organization (CRO) providing clinical development services to the biotechnology, pharmaceutical, and medical device industries. The Senior Data Engineer will work within the Information Technology team to support data engineering tasks and projects critical to the company's success.
Responsibilities:
• Utilize skills in development areas including data warehousing, business intelligence, and databases (Snowflake, ANSI SQL, SQL Server, T-SQL);
• Support programming/software development using Extract, Transform, and Load (ETL) and Extract, Load and Transform (ELT) tools, (dbt, Azure Data Factory, SSIS);
• Design, develop, enhance and support business intelligence systems primarily using Microsoft Power BI;
• Collect, analyze and document user requirements;
• Participate in software validation process through development, review, and/or execution of test plan/cases/scripts;
• Create software applications by following software development lifecycle process, which includes requirements gathering, design, development, testing, release, and maintenance;
• Communicate with team members regarding projects, development, tools, and procedures; and
• Provide end-user support including setup, installation, and maintenance for applications released.
Qualifications:
Required:
• Bachelor's Degree in Computer Science, Data Science, or a related field
• 5+ years of experience in Data Engineering
• Knowledge of developing dimensional data models and awareness of the advantages and limitations of Star Schema and Snowflake schema designs
• Solid ETL development, reporting knowledge based off intricate understanding of business process and measures
• Knowledge of REST API
• Basic knowledge of SQL Server databases
• Excellent analytical, written and oral communication skills
Preferred:
• Knowledge of Snowflake cloud data warehouse, Fivetran data integration and dbt transformations
• Knowledge of Python
• Knowledge of C#
• Knowledge of Azure development
Company:
Medpace, Inc., a clinical research organization, provides clinical development services for pharmaceutical and biotechnology Founded in 1992, the company is headquartered in Cincinnati, USA, with a team of 5001-10000 employees. The company is currently Late Stage.

What Medpace employees say

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Benefits

Hours and flexibility

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Get the full story on Breakroom

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About Medpace

Sourced by ZipRecruiter

Medpace is a globally recognized clinicial contract research organization (CRO) based in Cincinnati, OH, in the United States. Established in 1992, it operates in the healthcare sector, providing scientifically-driven outsourcing solutions for the development of drugs and medical devices. It offers comprehensive services like full-service clinical development services, regulatory affairs management, clinical pharmacology, data management, statistical analysis, and medical writing. By applying a scientifically-driven, therapeutically-focused, and patient-centric approach, Medpace's mission is to accelerate the global development of safe and effective medical therapies.

Industry

Medical equipment and supplies manufacturing

Company size

1,001 - 5,000 Employees

Headquarters location

Cincinnati, OH, US

Year founded

1992

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