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Senior Python Developer Jobs in Champaign, IL (NOW HIRING)

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Senior Python Developer information

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$55.1K

$142.2K

$195.3K

How much do senior python developer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python developer in Champaign, IL is $142,183.00, according to ZipRecruiter salary data. Most workers in this role earn between $121,700.00 and $163,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

How much does a senior Python developer make?

A senior Python developer's salary typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may have certifications or experience with cloud platforms, which can influence compensation.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Champaign, IL? The most popular types of Python Developer jobs in Champaign, IL are:
What job categories do people searching Senior Python Developer jobs in Champaign, IL look for? The top searched job categories for Senior Python Developer jobs in Champaign, IL are:
What cities near Champaign, IL are hiring for Senior Python Developer jobs? Cities near Champaign, IL with the most Senior Python Developer job openings:
Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Champaign, IL as of August 2026, with employment types broken down into 2% Internship, 74% Full Time, 18% Part Time, and 6% Contract. Highlights an 80% Physical, 6% Hybrid, and 14% Remote job distribution, with an average salary of $142,183 per year, or $68.4 per hour.

Senior Bioprocess Scientist / Engineer

Boston Bioprocess, Inc.

Champaign, IL • On-site

$90K - $110K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 12 days ago

Job description

Boston Bioprocess Inc. is a bioprocess optimization company; our mission is to help optimize bioprocesses helping precision fermentation businesses develop, optimize, and scale their production processes. Our company does this by combining hands-on work at our bench lab and pilot-scale facilities with the use of AI-powered optimization software. We are seeking a highly motivated Senior Bioprocess scientist or Bioprocess engineer to join our team.
The Senior Bioprocess Scientist/Engineer will work closely with the CSO and data science teams. The right candidate has substantial lab and/or plant experience across diverse bioprocesses and microbial systems, a strong command of software tools, and an enthusiasm for software development.
This role leads all efforts to support the development and improvement of our AI-powered optimization software for fermentation and purification processes at bench, pilot, and production scale. Responsibilities include designing experiments and generating data to enhance bioprocess parameters for proteins, lipids, amino acids, organic acids, polysaccharides, hydrocolloids, and enzymes across bacterial, yeast, and fungal systems.
While highly technical, the role requires regular engagement with clients, research organizations, and CDMO partners. Prospective candidates should understand that success requires technical expertise, but it also involves empathy, prompt communication, and a general client-service orientation.
Job responsibilities
  • Lead and manage bioprocess development projects, ensuring timely delivery and successful outcomes; provide technical expertise and guidance on experimental planning, process development, and troubleshooting
  • Design, execute, and troubleshoot experiments to optimize and scale-up fermentation and purification processes across bacterial, yeast, and fungal hosts for a range of products including proteins, lipids, amino acids, organic acids, polysaccharides, hydrocolloids, and enzymes
  • Act as a key liaison between the bioprocess and data science teams
  • Generate and analyze data to drive improvement of our AI-powered optimization software; prepare technical reports and presentations for internal and external stakeholders
  • Monitor industry trends, emerging technologies, and regulatory requirements in bioprocessing and apply insights to process and software optimization
  • Mentor junior scientists and engineers, providing technical guidance and supporting their professional development
  • Identify and lead initiatives to improve company workflows and operational excellence

Required Skills.
  • Ph.D. or M.Sc. in chemical or bioprocess engineering, biotechnology, biosciences, or a related field
  • At least 3-5 years of hands-on industry experience in bioprocess development and unit operations
  • Deep technical understanding and practical knowledge of microbial cultivation (bioreactor) and downstream processing - including centrifugation, filtration, precipitation, TFF, extraction, and drying - at bench and pilot scale
  • Proficiency in DoE and statistical tools for process optimization and characterization (QbD)
  • Experience with LIMS or similar data management systems
  • Proven experience producing bioproducts from diverse microbial hosts including bacteria, yeast, and fungi
  • Strong problem-solving skills with the ability to independently troubleshoot and resolve complex process challenges
  • Excellent communication and collaboration skills for working with internal teams, clients, and external partners
  • Strong project management and organizational skills, with the ability to manage multiple projects simultaneously

Nice to Have:
  • Bioprocess scale-up experience applying process engineering principles
  • Experience authoring SOPs and technical transfer documents
  • Understanding of microbial metabolism and its impact on product characteristics during optimization
  • Experience working in regulated environments (food grade, cGMP, APHIS, BSL-2)
  • Familiarity with Python scripting and Jupyter notebooks

The ideal candidate
  • We are a startup! Prospective candidates should enjoy working in a small team with minimal bureaucracy.
  • You'll enjoy working with us if you like building new things, are highly motivated, proactive and enjoy fast-paced culture, you can effectively work together with team members, partners, and clients in a collaborative environment.

What we offer
  • Salary of $90,000 to $110,000 depending on qualifications and experience.
  • Relocation assistance (if applicable)
  • Complete benefit package, including 401K match, ESOP, health, life, vision, and dental insurance, and four weeks paid vacation.
  • Significant company stock options.
  • Sponsorship and adjustment of work visas and immigration related support (must be currently a resident of the United States)

Boston Bioprocess Inc. is an equal opportunity employer and makes employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, and veteran status.

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