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Senior Python Developer Jobs in Alton, IL (NOW HIRING)

Biomerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Biomerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Biomerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

bioMérieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

bioMerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

BioFire Diagnostics

Sr. Software Engineer

Hazelwood, MO

$115K - $152K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Boeing

Senior DevSecOps Engineer

Berkeley, MO · On-site

$107K - $147K/yr

  • Medical

  • Life

  • Retirement

... or DevOps teams * 5+ years of experience in automated provisioning and configuring of software ... or Python * Experience with cloud platforms * Experience with Agile software development and ...

Boeing

Senior DevSecOps Engineer

Berkeley, MO · On-site

$107K - $147K/yr

  • Medical

  • Life

  • Retirement

... or DevOps teams * 5+ years of experience in automated provisioning and configuring of software ... or Python * Experience with cloud platforms * Experience with Agile software development and ...

Boeing

Software Engineer (Experienced, Senior)

Hazelwood, MO · On-site

$115K - $152K/yr

  • Medical

  • Life

  • Retirement

Software Engineer (Experienced, Senior) Company: The Boeing Company The Boeing Company is looking ... Python, C# and/or Assembly Language experience * Experience with GreenHills Integrity or other Real ...

Boeing Company

Software Engineer (Experienced, Senior)

Hazelwood, MO · On-site

$113K - $149K/yr

  • Medical

  • Life

  • Retirement

Software Engineer (Experienced, Senior) Company: The Boeing Company The Boeing Company is looking ... Python, C# and/or Assembly Language experience * Experience with GreenHills Integrity or other Real ...

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Showing results 41-60

All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Alton, IL

Senior Python Developer information

See Alton, IL salary details

$52.9K

$136.5K

$187.5K

How much do senior python developer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior python developer in Alton, IL is $136,525.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,800.00 and $157,200.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are popular job titles related to Senior Python Developer jobs in Alton, IL?

For Senior Python Developer jobs in Alton, IL, the most frequently searched job titles are:

What cities near Alton, IL are hiring for Senior Python Developer jobs?

Cities near Alton, IL with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Alton, IL as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 8% Part Time, and 7% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $136,525 per year, or $65.6 per hour.

Sr. Software Engineer

Biomerieux

Hazelwood, MO • On-site

$113K - $149K/yr

Other

Medical, Dental, Vision, Life, Retirement

Re-posted 22 days ago

Job description

Description
As a member of the R&D organization responsible for creating software for the development of innovative in vitro diagnostic solutions, the Senior Software Engineer contributes to the design and delivery of scalable, cloud-native software solutions by implementing modern software development practices, including microservices architecture, CI/CD, and infrastructure as code. The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and infrastructure as code solutions, and develops reliable data pipelines and governance practices. The Senior Software Engineer collaborates with cross-functional teams-including data engineering, product management, and architecture-to translate requirements into well-engineered solutions, uphold governance and security standards, and drive continuous improvement through code reviews, prototyping, and technology evaluation.
Primary Duties
  • Contributes to the design and implementation of multi-tier, distributed, and event-driven systems using cloud-native services and modern design patterns.
  • Implements infrastructure as code (IaC) solutions using AWS CloudFormation, containerized applications (Docker/Kubernetes), and automated deployment workflows.
  • Designs and develops microservices-based applications that leverage AWS/ECS/EKS to ensure scalability, security, and resilience.
  • Designs and develops data pipelines using AWS Lambda, Glue, and other AWS services, following operational standards for availability, performance, and disaster recovery.
  • Designs and develops RESTful APIs and integrates them with internal and external systems.
  • Designs and implements data storage solutions, including data lakes and warehouses that enable analytic and operational workloads.
  • Applies data governance practices-such as data quality, lineage, and security-within the systems and pipelines developed.
  • Implements integration strategies, APIs, and real-time/stream data solutions to ensure reliable and scalable data flows.
  • Contributes to technical design discussions and ensures solutions align with system engineering and architectural guidance.
  • Produces and maintains high-quality system designs, technical documentation, and implementation specifications.
  • Participates in design reviews, code reviews, and pair programming sessions to share knowledge and promote modern development practices.
  • Evaluates new technologies, tools, and frameworks, providing recommendations that support technical excellence and business needs.
  • Works closely with multidisciplinary teams to translate business requirements into technical designs and implementation plans.
  • Collaborates with cross-functional teams to integrate and optimize processes across teams.
  • Participates in proof-of-concept efforts by developing prototypes that validate design assumptions and accelerate solution delivery.
  • Performs other duties as assigned.

    • Qualifications
    Required Education, Training, and Experience
    • Bachelor's degree in Computer Science, Data Engineering, Software Engineering, Biology, Microbiology, Clinical Laboratory Science, Biomedical Engineering, or a related technical or scientific field
    • 7+ years of full stack development experience, including Java and modern web development frameworks such as Angular Suite.
    • Experience with AWS EC2, S3, Lambda Functions, ECS, EKS, RDS.
    • Proven experience with AWS integration/production systems using multiple managed services.
    • Solid grasp of security, compliance, and privacy fundamentals (least privilege, key management, network segmentation).
    • Experience developing and maintaining APIs or serverless patterns.
    • Influence and Code - Terraform (preferred) or AWS CDK/CloudFormation.
    • Implementation strategies for data integration.
    • Strong communication and collaboration skills.
    • Demonstrated architectural design patterns and automated quality gates to improve code health, reduce defects, and accelerate development.
    • Experience with relational databases (PostgreSQL, Oracle, etc.), advanced SQL.

    Preferred Education, Training, and Experience
    • Compliance experience (e.g., HIPAA, SOX, ISO 13485, 21 CFR, or other related SDLC concepts).
    • Experience developing solutions using Python, including scripting, automation, or data processing workflows.
    • Automated unit and integration E2E testing framework (PyUnit, Selenium, etc.).

    Knowledge, Skills, and Abilities
    • Acting with Honor and Being Open - Upholds and reflects bioMrieux's ethical principles and values.
    • Intellectual Honesty/Openness - Applies problem-solving to complex business challenges.
    • Building Relationships - Demonstrates effective verbal and written communication skills.
    • Creating the New...and Different - Influences change and persuades others to adopt new ideas, behaviors, or processes.
    • Understanding the Business - Demonstrates critical thinking, adaptability, time management, communication, problem-solving, and digital literacy.
    • Intermediate proficiency: applies skills independently in most situations; handles moderately complex tasks with occasional guidance.
    • Skilled in MS Office tools including Outlook, Teams, Word, and Excel.

    Working Conditions
    • Ability to remain in a stationary position for prolonged periods.
    • Travel required: 5% (including international travel).
    • Lifting required: No.
    • Other physical requirements: No.
    • Typical office setting with hybrid schedule ( 2 WFH, 3 days in office per week)

    The estimated salary range for this role is between $82,000-$115,000. This role is eligible to receive a variable annual bonus based on company, team, and individual performance per bioMerieux's bonus program. This range may differ from ranges offered for similar positions elsewhere in the country given differences in cost of living. Actual compensation within this range is determined based on the successful candidate's experience and will be presented in writing at the time of the offer.
    In addition, bioMrieux offers a competitive Total Rewards package that may include:
    A choice of medical (including prescription), dental, and vision plans providing nationwide coverage and telemedicine options
    Company-Provided Life and Accidental Death Insurance
    Short and Long-Term Disability Insurance
    Retirement Plan including a generous non-discretionary employer contribution and employer match.
    Adoption Assistance
    Wellness Programs
    Employee Assistance Program
    Commuter Benefits
    Various voluntary benefit offerings
    Discount programs
    Parental leaves
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