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Senior Python Developer Jobs in South Carolina (NOW HIRING)

Atlas Tech

Senior Systems Engineer

North Charleston, SC · On-site

$99K - $136K/yr

The Senior Systems Engineer is responsible for the engineering, hardening, baseline enforcement ... Proficiency in scripting and programming languages (e.g., Python, Bash, PowerShell). * Experience ...

Atlas Technologies Inc

Senior Systems Engineer

Charleston, SC · On-site

$99K - $136K/yr

The Senior Systems Engineer is responsible for the engineering, hardening, baseline enforcement ... Proficiency in scripting and programming languages (e.g., Python, Bash, PowerShell). * Experience ...

EPC POWER CORP.

Senior Software Engineer

Fountain Inn, SC · On-site

$122K - $138K/yr

Description EPC Power is looking to add a Senior Software Engineer to our engineering team. In this ... Strong understanding of python * Strong understanding of electrical circuits * Interested in power ...

EPC POWER CORP.

Senior Software Engineer

Fountain Inn, SC · On-site

$122K - $138K/yr

EPC Power is looking to add a Senior Software Engineer to our engineering team. In this role you ... Strong understanding of python * Strong understanding of electrical circuits * Interested in power ...

Scan source

Sr Full Stack Developer

Greenville, SC · On-site

$98K - $125K/yr

We are seeking a highly skilled Senior Full Stack Developer with 8+ years expertise in Microsoft ... Experience with Python development. * Experience with enterprise service and project platforms such ...

Apptad, Inc.

Senior AI Automation Engineer

Fort Mill, SC · On-site

$97K - $127K/yr

Job Title: Senior AI Automation Engineer Location: Fortmill, SC (Onsite) Duration: Contract ... Strong experience in Python development. * Hands-on experience with Generative AI, LLMs, and AI ...

Sunbelt Rentals

Sr. Software Engineer

Fort Mill, SC · On-site

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... CI/CD pipeline experience, especially Azure DevOps * Infrastructure-as-code experience (Bicep, ARM ...

Sunbelt Rentals, Inc.

Sr. Software Engineer

Fort Mill, SC · On-site

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... CI/CD pipeline experience, especially Azure DevOps * Infrastructure-as-code experience (Bicep, ARM ...

Sunbelt Rentals

Sr. Software Engineer

Fort Mill, SC · On-site

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... CI/CD pipeline experience, especially Azure DevOps * Infrastructure-as-code experience (Bicep, ARM ...

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All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in South Carolina

Senior Python Developer information

See South Carolina salary details

$51K

$131.7K

$181K

How much do senior python developer jobs pay per year?

As of Aug 22, 2026, the average yearly pay for senior python developer in South Carolina is $131,747.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,700.00 and $151,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in South Carolina?

The most popular types of Python Developer jobs in South Carolina are:

What are popular job titles related to Senior Python Developer jobs in South Carolina?

For Senior Python Developer jobs in South Carolina, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in South Carolina look for?

The top searched job categories for Senior Python Developer jobs in South Carolina are:

What cities in South Carolina are hiring for Senior Python Developer jobs?

Cities in South Carolina with the most Senior Python Developer job openings:

What are popular job titles related to Senior Python Developer jobs in SC?

For Senior Python Developer jobs in SC, the most frequently searched job titles are:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in South Carolina as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 9% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $131,747 per year, or $63.3 per hour.

Senior Infrastructure and Platform Engineer

Forge Forward, Inc.

Charleston, SC • On-site

$90 - $130/hr

Other

Posted 4 days ago

Job description

Location: Charleston, SC

REQ: 026_019

Forge Forward is searching for a Senior Infrastructure & Platform Engineer to support a client in Charleston, SC. This is an on-site position so any interested candidates must be able to be in the office every day. US citizenship and a minimum Secret clearance are required. If you do not meet these qualifications, you cannot be considered.

The position requires a minimum seven (7) years of experience supporting enterprise C4I systems with a focus on infrastructure engineering, virtualization, and platform automation within secure DoD environments. This position serves as a senior technical authority responsible for the design, engineering, integration, and lifecycle management of hybrid infrastructure platforms spanning compute, storage, virtualization, and containerized environments.

The Senior Infrastructure & Platform Engineer will design and sustain enterprise VMware-based environments while expanding into broader infrastructure domains including hardware platforms, storage systems, backup/recovery solutions, and automation frameworks. This role requires a hands‑on engineer capable of bridging traditional datacenter infrastructure with modern DevSecOps and platform engineering practices.

The candidate must independently troubleshoot complex system and infrastructure issues, lead engineering and integration efforts across multiple technology domains, and ensure compliance with DoD cybersecurity requirements. The engineer will operate across lab and production environments, supporting modernization initiatives that incorporate automation, Infrastructure as Code (IaC), and containerized workloads.

This is a senior, hands‑on role requiring strong technical leadership, cross‑domain expertise, and the ability to drive infrastructure evolution within mission‑critical environments.

Functional Responsibilities and Skills:

  • Engineer and sustain enterprise virtualization platforms (VMware vSphere, ESXi, vCenter, vSAN)
  • Design and support hybrid infrastructure spanning compute hardware, virtualization, and platform services
  • Contribute to datacenter hardware lifecycle activities including server deployment, configuration, and optimization
  • Support and integrate enterprise storage solutions (SAN/NAS) and associated performance tuning
  • Administer and support enterprise backup and disaster recovery platforms (e.g., Rubrik or equivalent)
  • Develop and maintain automation using tools such as Ansible, Terraform, PowerShell, and Bash
  • Implement Infrastructure as Code (IaC) for provisioning, configuration, and system standardization
  • Support containerized environments and orchestration platforms (Kubernetes or equivalent)
  • Troubleshoot complex issues across compute, storage, virtualization, and platform layers
  • Ensure systems are engineered and maintained in accordance with DISA STIGs and DoD cybersecurity requirements
  • Support RMF activities, including control validation, POA&M development, and continuous monitoring
  • Collaborate across engineering, cybersecurity, and program teams to deliver integrated solutions
  • Participate in technical reviews, architecture discussions, and configuration control boards
  • Produce and maintain technical documentation including designs, implementation plans, and operational procedures
  • Provide technical leadership and mentorship within a multi‑disciplinary engineering team

Requirements:

  • Minimum seven (7) years of experience supporting enterprise C4I systems with a focus on infrastructure engineering, virtualization, and platform automation within secure DoD environments
  • US citizen holding a Secret clearance at minimum with current SSBI/T5 investigation, TS/SCI clearance desired
  • CompTIA Security+ certification
  • DoD Cybersecurity Workforce IAT Level II
  • Bachelor’s degree in IT or related technical field desired

Desired Skills:

  • Experience supporting Navy C4I or similar DoD environments
  • Experience with VMware Cloud Foundation (VCF) and/or VMware Tanzu
  • Familiarity with software‑defined networking (NSX‑T or equivalent)
  • Advanced experience with storage platforms and data protection strategies
  • Strong understanding of DevSecOps principles and CI/CD pipeline integration
  • Proficiency in scripting/programming (Python, PowerShell, Bash)
  • Experience with Git‑based version control and automation pipelines
  • Experience supporting classified environments with privileged access
  • Familiarity with hybrid cloud or cloud‑adjacent architectures
  • Excellent communication and collaboration skills across technical teams
  • VMware Certified Professional (VCP‑DCV or NV), Certified Kubernetes Administrator (CKA) or equivalent, HashiCorp Terraform Associate or similar IaC certification
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