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Senior Python Developer Jobs in South Carolina (NOW HIRING)

DAS Technology Group

Senior Software Engineer

Charleston, SC · On-site

$114K - $151K/yr

Senior Software Engineer/ Software Engineer IV Department: Design Engineering Overview: We are ... Python. * Proven (R&D) experience with innovative engineering solutions. * Strong analytical and ...

DAS Technology Group

Senior Software Engineer

Charleston, SC · On-site

$114K - $151K/yr

Senior Software Engineer/ Software Engineer IV Department: Design Engineering Overview: We are ... Python. * Proven (R&D) experience with innovative engineering solutions. * Strong analytical and ...

PB consulting

Senior Hadoop Developer

Tega Cay, SC · On-site

Proficiency in SQL, Shell scripting, and Python automation. * Experience with Cloudera Data ... Collaborate with application, data engineering, and platform teams during incident, problem, and ...

PB consulting

Senior Hadoop Developer

Fort Mill, SC · On-site

Proficiency in SQL, Shell scripting, and Python automation. * Experience with Cloudera Data ... Collaborate with application, data engineering, and platform teams during incident, problem, and ...

PB consulting

Senior Hadoop Developer

Lake Wylie, SC · On-site

Proficiency in SQL, Shell scripting, and Python automation. * Experience with Cloudera Data ... Collaborate with application, data engineering, and platform teams during incident, problem, and ...

AERONIX INC

Senior Software Test Engineer

Greenville, SC · On-site

$100K - $140K/yr

... developer efficiency, treating test infrastructure as critical software. * Work collaboratively ... Experience with scripting languages like Python and Bash. * Experience integrating software with ...

Actalent

Senior Software Engineer

Greenville, SC · On-site

$115K - $151K/yr

Senior Software Engineer We are seeking a highly skilled Senior Embedded Software Engineer to ... Proficiency in Python for scripting, automation, and test development. * Experience with ...

Accord Technologies Inc.

Sr. Java developer

Rock Hill, SC · On-site

$47.50 - $60.50/hr

Java Developer Location: Fort Mill, USA Work Split: 75% Development / 25% L3 Support Position type ... Python core concepts and proficiency with its libraries and framework * Familiarity with ...

PB consulting

Senior Site Reliability Engineer

Tega Cay, SC

$49.75 - $66/hr

Develop automation and troubleshooting scripts using Python and Bash. * Lead incident response ... DevOps. * Strong experience with AWS cloud services, including ECS, EKS, EC2, Lambda, RDS, S3, and ...

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All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in South Carolina

Senior Python Developer information

See South Carolina salary details

$51K

$131.7K

$181K

How much do senior python developer jobs pay per year?

As of Sep 13, 2026, the average yearly pay for senior python developer in South Carolina is $131,747.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,700.00 and $151,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in South Carolina?

The most popular types of Python Developer jobs in South Carolina are:

What are popular job titles related to Senior Python Developer jobs in South Carolina?

For Senior Python Developer jobs in South Carolina, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in South Carolina look for?

The top searched job categories for Senior Python Developer jobs in South Carolina are:

What cities in South Carolina are hiring for Senior Python Developer jobs?

Cities in South Carolina with the most Senior Python Developer job openings:

What are popular job titles related to Senior Python Developer jobs in SC?

For Senior Python Developer jobs in SC, the most frequently searched job titles are:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in South Carolina as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 9% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $131,747 per year, or $63.3 per hour.

Senior AWS Full Stack Engineer

Columbia, SC • On-site

System One Holdings, LLC
Business Consulting Services • 5 - 10K employees
Learn more about System One Holdings, LLCexternal

$108K/yr

Full-time

This job post has expired today. Applications are no longer accepted.

Job description

Job Title: Senior AWS Full Stack Engineer
Location: Knoxville, TN, Columbia SC or Lafayette, LA or Birmingham, AL
Description:
Senior AWS Full Stack Engineer to join a team supporting enterprise applications within the financial services industry. This is a hands-on development role focused on building, enhancing, and supporting scalable applications using Java, Spring Boot, Angular, Python, and AWS.
The ideal candidate brings strong full stack development experience, solid AWS knowledge, and practical experience using AI/Generative AI tools as part of the software development lifecycle. The engineer will work across application layers, contribute to technical decisions, translate business requirements into working solutions, and help improve development efficiency through modern engineering and AI assisted practices.
Senior AWS Full Stack Engineer to join a team supporting enterprise applications within the financial services industry. This is a hands-on development role focused on building, enhancing, and supporting scalable applications using Java, Spring Boot, Angular, Python, and AWS.
The ideal candidate brings strong full stack development experience, solid AWS knowledge, and practical experience using AI/Generative AI tools as part of the software development lifecycle. The engineer will work across application layers, contribute to technical decisions, translate business requirements into working solutions, and help improve development efficiency through modern engineering and AI assisted practices.
Key Responsibilities
. Develop and maintain full stack applications using Java/Spring Boot, Angular, and Python.
. Build and support cloud native applications and services within AWS heavy environments.
. Work with AWS services such as Lambda, ECS/EKS, S3, API Gateway, DynamoDB, and RDS.
. Develop and support APIs, microservices, integrations, and distributed application components.
. Use GenAI and AI assisted development tools, including GitHub Copilot, ChatGPT, and LLM based solutions, to improve development productivity and code quality.
. Apply LLMs and agent based/agentic workflows where appropriate to automate development tasks and enhance application capabilities.
. Create unit and automated tests and participate in peer and AI assisted code reviews.
. Translate business and functional requirements into reliable, maintainable technical solutions.
. Work closely with developers, product partners, and other stakeholders in an Agile delivery environment.
. Mentor less experienced developers while remaining actively involved in hands on development and troubleshooting.
. Contribute to CI/CD, DevOps, testing, and application reliability practices.
Required qualifications to be successful in this role
. 5+ years of full stack software engineering experience, preferably supporting large scale enterprise applications.
. Strong hands-on development experience with Java and Spring Boot.
. Strong front end development experience with Angular.
. Working proficiency with Python for application development, automation, or AI related use cases.
. Strong hands on experience developing and deploying applications on AWS.
. Experience with relevant AWS services such as Lambda, ECS/EKS, S3, API Gateway, DynamoDB, and RDS.
. Experience developing REST APIs, microservices, and distributed applications.
. Practical experience using GenAI/AI development tools, such as GitHub Copilot, ChatGPT, or similar tools, as part of day to day software development.
. Understanding of LLMs, LLM APIs, and agentic/agent based workflows, with experience applying them to software development or application capabilities.
. Experience with CI/CD pipelines, automated testing, Git based development, and modern DevOps practices.
. Strong understanding of unit testing, code reviews, debugging, and software engineering best practices.
. Ability to work independently, solve complex technical problems, and take ownership of development initiatives.
. Strong communication and collaboration skills, including the ability to mentor junior engineers.
. Financial services or other large enterprise application experience is a plus.
Education:
Bachelor's degree in Computer Science, Software Engineering, Information Technology, or a related technical field
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About System One

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System One helps employers get work done more efficiently and economically without compromising quality. Over our 35+ year history, we've helped connect thousands of talented people with innovative companies. The excitement of a perfect fit motivates us every single day.

Industry

Business consulting services and recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Pittsburgh, PA, US

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